hnRNP R Inhibitors
hnRNP R inhibitors belong to a class of chemical compounds designed to target and modulate the activity of the heterogeneous nuclear ribonucleoprotein R (hnRNP R) protein. hnRNP R is a member of the hnRNP family, which are RNA-binding proteins that play crucial roles in various aspects of RNA processing and gene expression regulation within the nucleus of eukaryotic cells. These proteins are involved in functions such as pre-mRNA splicing, RNA transport, and mRNA stability. Inhibitors of hnRNP R are developed to interact with this protein, interfering with its RNA-binding capabilities and affecting its role in RNA metabolism.
Typically, hnRNP R inhibitors are small molecules or compounds designed to bind to hnRNP R and disrupt its interactions with target RNA molecules or other protein partners within the ribonucleoprotein complexes. By doing so, these inhibitors may influence RNA processing events, such as alternative splicing or mRNA stability, that hnRNP R is involved in. Research into hnRNP R inhibitors can provide valuable insights into the molecular mechanisms governing RNA metabolism and gene expression regulation, contributing to our understanding of post-transcriptional gene regulation.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $74.00 $243.00 $731.00 $2572.00 $21848.00 | 53 | |
A compound that intercalates into DNA, preventing transcription by RNA polymerase, which could inhibit hnRNP R expression at the transcription level. | ||||||
α-Amanitin | 23109-05-9 | sc-202440 sc-202440A | 1 mg 5 mg | $269.00 $1050.00 | 26 | |
A potent inhibitor of RNA polymerase II which could block mRNA synthesis for proteins including hnRNP R. | ||||||
Triptolide | 38748-32-2 | sc-200122 sc-200122A | 1 mg 5 mg | $90.00 $204.00 | 13 | |
A diterpene triepoxide that inhibits the transcription of a wide range of genes, potentially including that encoding hnRNP R. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
A nucleoside analog that can incorporate into DNA and RNA, potentially leading to the inhibition of methylation and affecting gene expression. | ||||||
DRB | 53-85-0 | sc-200581 sc-200581A sc-200581B sc-200581C | 10 mg 50 mg 100 mg 250 mg | $43.00 $189.00 $316.00 $663.00 | 6 | |
Inhibits RNA Polymerase II transcription elongation, which could decrease hnRNP R mRNA synthesis. | ||||||
Cordycepin | 73-03-0 | sc-203902 | 10 mg | $101.00 | 5 | |
An adenosine analogue that can terminate mRNA elongation and could potentially inhibit the production of hnRNP R mRNA. | ||||||
Chetomin | 1403-36-7 | sc-202535 sc-202535A | 1 mg 5 mg | $186.00 $674.00 | 10 | |
A compound that disrupts the structure of the nucleolus and inhibits RNA polymerase I transcription, potentially affecting hnRNP R expression. | ||||||
Rocaglamide | 84573-16-0 | sc-203241 sc-203241A sc-203241B sc-203241C sc-203241D | 100 µg 1 mg 5 mg 10 mg 25 mg | $275.00 $474.00 $1639.00 $2497.00 $5344.00 | 4 | |
A natural product that inhibits translation initiation and could reduce the synthesis of proteins such as hnRNP R. | ||||||
Harringtonin | 26833-85-2 | sc-204771 sc-204771A sc-204771B sc-204771C sc-204771D | 5 mg 10 mg 25 mg 50 mg 100 mg | $250.00 $367.00 $548.00 $730.00 $980.00 | 30 | |
An alkaloid that inhibits protein translation at the initiation step, which could lead to reduced expression of hnRNP R. | ||||||
Cycloheximide | 66-81-9 | sc-3508B sc-3508 sc-3508A | 100 mg 1 g 5 g | $41.00 $84.00 $275.00 | 127 | |
An inhibitor of eukaryotic protein synthesis, acting on the 60S ribosomal subunit, potentially decreasing hnRNP R levels by blocking translation. | ||||||