Date published: 2025-10-19

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HNF-6 Activators

HNF-6 Activators belong to a specific category of chemical compounds that play a crucial role in regulating gene expression and controlling various biological processes within living organisms. HNF-6, which stands for Hepatocyte Nuclear Factor 6, is a transcription factor that is primarily found in the liver and pancreas, where it serves as a key regulator of genes involved in the development and maintenance of these vital organs. HNF-6 activators are substances that can modulate the activity of HNF-6, either by enhancing or inhibiting its function, and in turn, influence the expression of target genes associated with organ development, metabolism, and other essential physiological functions.

These activators are often small molecules or compounds that interact with HNF-6 at the molecular level, affecting its binding to specific DNA sequences or its ability to recruit co-factors that promote gene transcription. By doing so, HNF-6 activators have the potential to impact various biological processes, including the synthesis and regulation of enzymes and proteins involved in metabolism, as well as the differentiation and maturation of hepatocytes and pancreatic cells. Understanding the mechanisms by which HNF-6 activators function can provide valuable insights into the intricate molecular pathways governing organ development and function such as advancing our knowledge of developmental biology and molecular genetics.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Retinoic Acid, all trans

302-79-4sc-200898
sc-200898A
sc-200898B
sc-200898C
500 mg
5 g
10 g
100 g
$65.00
$319.00
$575.00
$998.00
28
(1)

Retinoic acid, a metabolite of vitamin A, is known to influence cell differentiation and may play a role in inducing HNF-6 expression in liver cells.

Dexamethasone

50-02-2sc-29059
sc-29059B
sc-29059A
100 mg
1 g
5 g
$76.00
$82.00
$367.00
36
(1)

Dexamethasone, a synthetic corticosteroid, has been shown to affect gene expression in liver cells, potentially including HNF-6.

Insulin

11061-68-0sc-29062
sc-29062A
sc-29062B
100 mg
1 g
10 g
$153.00
$1224.00
$12239.00
82
(1)

Insulin can modulate the expression of various genes in the liver and may influence HNF-6 expression as part of metabolic regulation.

Glucagon trifluoroacetic acid salt

9007-92-5 (free base)sc-495801
1 mg
$480.00
(0)

Glucagon, a peptide hormone, plays a role in glucose metabolism and may influence HNF-6 expression in the liver.

L-3,3′,5-Triiodothyronine, Sodium Salt

55-06-1sc-205725
250 mg
$113.00
(1)

T3 influences metabolic processes in the liver, and it may play a role in modulating HNF-6 expression.

Forskolin

66575-29-9sc-3562
sc-3562A
sc-3562B
sc-3562C
sc-3562D
5 mg
50 mg
1 g
2 g
5 g
$76.00
$150.00
$725.00
$1385.00
$2050.00
73
(3)

Forskolin is known to elevate intracellular cAMP levels, potentially influencing HNF-6 expression in certain cell types.

Lithium

7439-93-2sc-252954
50 g
$214.00
(0)

Lithium chloride can affect various signaling pathways and may have an impact on HNF-6 expression.

Sodium Butyrate

156-54-7sc-202341
sc-202341B
sc-202341A
sc-202341C
250 mg
5 g
25 g
500 g
$30.00
$46.00
$82.00
$218.00
19
(3)

Sodium butyrate, a short-chain fatty acid, can act as a histone deacetylase inhibitor, potentially influencing HNF-6 expression.

Hydrogen Peroxide

7722-84-1sc-203336
sc-203336A
sc-203336B
100 ml
500 ml
3.8 L
$30.00
$60.00
$93.00
27
(1)

As an oxidative stress agent, hydrogen peroxide might influence various signaling pathways, potentially affecting HNF-6 expression.