Histone H2B.S Inhibitors
Histone H2B.S inhibitors constitute a specialized chemical class designed to selectively target and modulate the function of H2B.S histone proteins. Within the diverse realm of histone variants, H2B.S plays a crucial role in the regulation of chromatin structure and gene expression. As an integral component of nucleosomes, H2B.S contributes significantly to the compaction of DNA, exerting influence over the dynamics of gene regulation within the cellular context. The inhibitors tailored for Histone H2B.S are intricately designed to interact with the specific molecular structure of this histone variant, with the objective of perturbing its normal interactions within the nucleosome and potentially influencing the broader chromatin landscape.
The molecular architecture of Histone H2B.S inhibitors is precisely crafted to engage specific binding sites on H2B.S, inducing changes in its conformation and dynamics. This interaction holds the potential to impact the accessibility of DNA, thereby influencing the regulatory processes governing gene expression. In laboratory settings, researchers leverage these inhibitors as powerful tools to dissect the nuanced roles of H2B.S in various cellular processes, contributing to an enhanced understanding of chromatin biology. By manipulating the function of H2B.S, scientists aim to unravel the intricate mechanisms of gene regulation, shedding light on the broader implications of epigenetic processes for cellular function and development. The exploration of Histone H2B.S inhibitors stands at the forefront of advancing our comprehension of chromatin dynamics and the finely tuned orchestration of gene expression within the cellular milieu.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
MS-275 | 209783-80-2 | sc-279455 sc-279455A sc-279455B | 1 mg 5 mg 25 mg | $24.00 $90.00 $212.00 | 24 | |
This benzamide histone deacetylase inhibitor may alter chromatin structure and influence gene expression patterns. | ||||||
Panobinostat | 404950-80-7 | sc-208148 | 10 mg | $200.00 | 9 | |
A potent histone deacetylase inhibitor that can change acetylation patterns, potentially affecting gene transcription. | ||||||
Romidepsin | 128517-07-7 | sc-364603 sc-364603A | 1 mg 5 mg | $218.00 $634.00 | 1 | |
It is another histone deacetylase inhibitor that may modify chromatin architecture and gene expression. | ||||||
Anacardic Acid | 16611-84-0 | sc-202463 sc-202463A | 5 mg 25 mg | $102.00 $204.00 | 13 | |
This compound can inhibit histone acetyltransferase, which might lead to changes in histone acetylation and gene regulation. | ||||||
Garcinol | 78824-30-3 | sc-200891 sc-200891A | 10 mg 50 mg | $124.00 $502.00 | 13 | |
Inhibits histone acetyltransferases, which could affect gene expression by changing histone acetylation. | ||||||
Histone Lysine Methyltransferase Inhibitor Inhibitor | 935693-62-2 (free base) | sc-202651 | 5 mg | $151.00 | 4 | |
A histone methyltransferase inhibitor that may affect histone methylation status and gene expression. | ||||||
Chaetocin | 28097-03-2 | sc-200893 | 200 µg | $126.00 | 5 | |
Known to inhibit histone methyltransferase, potentially altering chromatin structure and gene expression. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $45.00 $164.00 $200.00 $402.00 $575.00 $981.00 $2031.00 | 46 | |
Acts as a tyrosine kinase inhibitor and has been shown to affect DNA methylation and histone acetylation. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
This compound can modulate various signaling pathways and has been shown to affect histone acetylation and methylation. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
A polyphenol that may influence DNA methylation and histone acetylation, potentially altering gene expression. | ||||||