The chemical class known as HD-PTP Activators refers to a group of compounds or molecules that have the capability to enhance the activity or function of the enzyme HD-PTP, also known as histidine phosphatase. HD-PTP is a protein tyrosine phosphatase enzyme encoded by the PTPN23 gene, and it plays a crucial role in various cellular processes. Its primary function is the dephosphorylation of tyrosine residues in proteins, which can have a profound impact on cell signaling, regulation of cellular processes, and overall cell function.
Activation of HD-PTP by these activators can modulate signal transduction pathways and cellular responses by regulating the phosphorylation status of specific proteins. These activators may bind to HD-PTP directly or indirectly, leading to increased catalytic activity or altered substrate specificity. By doing so, they can influence processes such as cell growth, differentiation, migration, and intracellular communication. HD-PTP activation is an active area of research in cell biology and signal transduction. In summary, HD-PTP Activators represent a class of compounds that can enhance the enzymatic activity of HD-PTP, a protein tyrosine phosphatase involved in regulating cellular signaling pathways. Their ability to modulate tyrosine phosphorylation events within cells makes them important molecules in the study of cell biology and signal transduction processes. Further research into these activators may provide valuable insights into their applications in various cellular contexts.
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Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
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MG-132 [Z-Leu- Leu-Leu-CHO] | 133407-82-6 | sc-201270 sc-201270A sc-201270B | 5 mg 25 mg 100 mg | $56.00 $260.00 $980.00 | 163 | |
These compounds inhibit protein degradation and might increase HD-PTP levels due to reduced proteasomal degradation. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
These compounds can affect gene expression broadly and may upregulate HD-PTP as part of changes in chromatin structure. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
mTOR inhibitors affect cellular growth pathways, which could intersect with HD-PTP regulation. | ||||||
Etoposide (VP-16) | 33419-42-0 | sc-3512B sc-3512 sc-3512A | 10 mg 100 mg 500 mg | $32.00 $170.00 $385.00 | 63 | |
DNA damage can lead to cellular stress responses that may include upregulation of HD-PTP. | ||||||
Hydrogen Peroxide | 7722-84-1 | sc-203336 sc-203336A sc-203336B | 100 ml 500 ml 3.8 L | $30.00 $60.00 $93.00 | 27 | |
Oxidative stress is known to modulate various signaling pathways, potentially affecting HD-PTP expression. | ||||||
Cobalt(II) chloride | 7646-79-9 | sc-252623 sc-252623A | 5 g 100 g | $63.00 $173.00 | 7 | |
Hypoxia-inducible factors (HIFs) may regulate HD-PTP under low oxygen conditions. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
As a regulator of gene expression, retinoic acid could potentially upregulate HD-PTP. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Lithium impacts the Wnt signaling pathway, which might intersect with pathways regulating HD-PTP expression. |