H2al3 inhibitors constitute a specific class of chemical compounds designed to modulate the activity of the H2al3 protein. H2al3, also known as histocompatibility 2, A region locus 3, is a protein component of the major histocompatibility complex (MHC) system, particularly in mice. The MHC system plays a pivotal role in the immune response by facilitating the presentation of antigenic peptides to T cells, allowing the immune system to recognize and respond to foreign pathogens effectively. H2al3, like other MHC molecules, is intricately involved in the complex process of antigen presentation, which is fundamental for initiating immune responses against infections. The development of H2al3 inhibitors is primarily motivated by the objective of selectively interacting with the H2al3 protein, potentially influencing its antigen-presenting activity and impacting immune recognition processes.
Typically, H2al3 inhibitors consist of small molecules or chemical compounds that are meticulously engineered to bind to H2al3, targeting either its active site or allosteric sites. This interaction can lead to the modulation of H2al3's behavior, potentially affecting its ability to present antigenic peptides to T cells and, consequently, influencing the immune response against foreign antigens. Researchers are dedicated to unraveling the molecular mechanisms and functions of H2al3 within the MHC system, aiming to gain insights into the complex immune recognition processes. The development of H2al3 inhibitors represents an ongoing and dynamic area of research within the fields of immunology and molecular pharmacology, contributing significantly to our understanding of the immune system's functioning and its role in detecting and responding to foreign antigens.
SEE ALSO...
Items 1 to 10 of 12 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
An mTOR inhibitor, which can lead to altered transcription and potentially downregulate histone gene expression through cell cycle arrest. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
An HDAC inhibitor, altering chromatin structure and potentially decreasing histone gene transcription by affecting histone acetylation. | ||||||
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $130.00 $270.00 | 37 | |
Also an HDAC inhibitor, it may change chromatin accessibility and reduce the transcription of various genes, including histones. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $30.00 $46.00 $82.00 $218.00 | 19 | |
A short-chain fatty acid and HDAC inhibitor that can affect gene expression by altering the histone acetylation state. | ||||||
Rocaglamide | 84573-16-0 | sc-203241 sc-203241A sc-203241B sc-203241C sc-203241D | 100 µg 1 mg 5 mg 10 mg 25 mg | $270.00 $465.00 $1607.00 $2448.00 $5239.00 | 4 | |
A natural product that inhibits eukaryotic initiation factor 4A (eIF4A), possibly affecting translation of histone mRNA. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
A polyphenol that can modulate DNA methylation and histone acetylation, potentially influencing gene expression. | ||||||
Anacardic Acid | 16611-84-0 | sc-202463 sc-202463A | 5 mg 25 mg | $100.00 $200.00 | 13 | |
A natural compound known to inhibit histone acetyltransferase, potentially suppressing gene expression. | ||||||
MS-275 | 209783-80-2 | sc-279455 sc-279455A sc-279455B | 1 mg 5 mg 25 mg | $24.00 $88.00 $208.00 | 24 | |
A benzamide HDAC inhibitor that may modulate chromatin structure and affect gene transcription levels. | ||||||
Sirtinol | 410536-97-9 | sc-205976 sc-205976A | 1 mg 5 mg | $37.00 $111.00 | 14 | |
An inhibitor of sirtuin HDACs, which may lead to altered histone modification and gene expression, including histone genes. | ||||||
Scriptaid | 287383-59-9 | sc-202807 sc-202807A | 1 mg 5 mg | $63.00 $179.00 | 11 | |
A broad-spectrum HDAC inhibitor that can modify chromatin structure and potentially affect expression of various genes. | ||||||