Date published: 2025-11-24

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H2al3 Inhibitors

H2al3 inhibitors constitute a specific class of chemical compounds designed to modulate the activity of the H2al3 protein. H2al3, also known as histocompatibility 2, A region locus 3, is a protein component of the major histocompatibility complex (MHC) system, particularly in mice. The MHC system plays a pivotal role in the immune response by facilitating the presentation of antigenic peptides to T cells, allowing the immune system to recognize and respond to foreign pathogens effectively. H2al3, like other MHC molecules, is intricately involved in the complex process of antigen presentation, which is fundamental for initiating immune responses against infections. The development of H2al3 inhibitors is primarily motivated by the objective of selectively interacting with the H2al3 protein, potentially influencing its antigen-presenting activity and impacting immune recognition processes.

Typically, H2al3 inhibitors consist of small molecules or chemical compounds that are meticulously engineered to bind to H2al3, targeting either its active site or allosteric sites. This interaction can lead to the modulation of H2al3's behavior, potentially affecting its ability to present antigenic peptides to T cells and, consequently, influencing the immune response against foreign antigens. Researchers are dedicated to unraveling the molecular mechanisms and functions of H2al3 within the MHC system, aiming to gain insights into the complex immune recognition processes. The development of H2al3 inhibitors represents an ongoing and dynamic area of research within the fields of immunology and molecular pharmacology, contributing significantly to our understanding of the immune system's functioning and its role in detecting and responding to foreign antigens.

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Rapamycin

53123-88-9sc-3504
sc-3504A
sc-3504B
1 mg
5 mg
25 mg
$62.00
$155.00
$320.00
233
(4)

An mTOR inhibitor, which can lead to altered transcription and potentially downregulate histone gene expression through cell cycle arrest.

Trichostatin A

58880-19-6sc-3511
sc-3511A
sc-3511B
sc-3511C
sc-3511D
1 mg
5 mg
10 mg
25 mg
50 mg
$149.00
$470.00
$620.00
$1199.00
$2090.00
33
(3)

An HDAC inhibitor, altering chromatin structure and potentially decreasing histone gene transcription by affecting histone acetylation.

Suberoylanilide Hydroxamic Acid

149647-78-9sc-220139
sc-220139A
100 mg
500 mg
$130.00
$270.00
37
(2)

Also an HDAC inhibitor, it may change chromatin accessibility and reduce the transcription of various genes, including histones.

Sodium Butyrate

156-54-7sc-202341
sc-202341B
sc-202341A
sc-202341C
250 mg
5 g
25 g
500 g
$30.00
$46.00
$82.00
$218.00
19
(3)

A short-chain fatty acid and HDAC inhibitor that can affect gene expression by altering the histone acetylation state.

Rocaglamide

84573-16-0sc-203241
sc-203241A
sc-203241B
sc-203241C
sc-203241D
100 µg
1 mg
5 mg
10 mg
25 mg
$270.00
$465.00
$1607.00
$2448.00
$5239.00
4
(1)

A natural product that inhibits eukaryotic initiation factor 4A (eIF4A), possibly affecting translation of histone mRNA.

(−)-Epigallocatechin Gallate

989-51-5sc-200802
sc-200802A
sc-200802B
sc-200802C
sc-200802D
sc-200802E
10 mg
50 mg
100 mg
500 mg
1 g
10 g
$42.00
$72.00
$124.00
$238.00
$520.00
$1234.00
11
(1)

A polyphenol that can modulate DNA methylation and histone acetylation, potentially influencing gene expression.

Anacardic Acid

16611-84-0sc-202463
sc-202463A
5 mg
25 mg
$100.00
$200.00
13
(1)

A natural compound known to inhibit histone acetyltransferase, potentially suppressing gene expression.

MS-275

209783-80-2sc-279455
sc-279455A
sc-279455B
1 mg
5 mg
25 mg
$24.00
$88.00
$208.00
24
(2)

A benzamide HDAC inhibitor that may modulate chromatin structure and affect gene transcription levels.

Sirtinol

410536-97-9sc-205976
sc-205976A
1 mg
5 mg
$37.00
$111.00
14
(1)

An inhibitor of sirtuin HDACs, which may lead to altered histone modification and gene expression, including histone genes.

Scriptaid

287383-59-9sc-202807
sc-202807A
1 mg
5 mg
$63.00
$179.00
11
(2)

A broad-spectrum HDAC inhibitor that can modify chromatin structure and potentially affect expression of various genes.