GTL3 Inhibitors
GTL3 inhibitors represent a class of chemical compounds specifically engineered to inhibit the activity of GTL3, a protein that is understood to be involved in a range of cellular processes, including those related to gene expression and regulation. The precise biological function of GTL3 is not fully delineated, but it is believed to play a role in the modification of transfer RNAs (tRNAs) and potentially in the regulation of other cellular pathways through interactions with various macromolecules. GTL3 inhibitors work by binding to the GTL3 protein and impeding its ability to interact with its natural substrates or partner proteins. This inhibition can result from the inhibitor occupying the active site of the protein, altering its conformation, or competing with the natural substrates for binding, thus preventing GTL3 from exerting its normal function within the cell.
The development of GTL3 inhibitors is a complex task that requires an extensive understanding of the protein's structure and the biochemical pathways in which it operates. The inhibitors must be designed to specifically target key domains of GTL3 that are involved in its catalytic activity or its interactions with other cellular components.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Cytochalasin D | 22144-77-0 | sc-201442 sc-201442A | 1 mg 5 mg | $165.00 $486.00 | 64 | |
Cytochalasin D interferes with actin polymerization. By affecting the cytoskeleton, it can indirectly disrupt the support and functionality of cilia where GTL3 operates, inhibiting GTL3 function. | ||||||
Nocodazole | 31430-18-9 | sc-3518B sc-3518 sc-3518C sc-3518A | 5 mg 10 mg 25 mg 50 mg | $59.00 $85.00 $143.00 $247.00 | 38 | |
Nocodazole disrupts microtubule polymerization. Cilia are rich in microtubules, so its disruption can alter ciliary structure, thereby inhibiting GTL3's role in ciliary movement. | ||||||
Colchicine | 64-86-8 | sc-203005 sc-203005A sc-203005B sc-203005C sc-203005D sc-203005E | 1 g 5 g 50 g 100 g 500 g 1 kg | $100.00 $321.00 $2289.00 $4484.00 $18207.00 $34749.00 | 3 | |
Colchicine inhibits microtubule polymerization. This can impact ciliary structure and indirectly inhibit GTL3's function within cilia. | ||||||
Mebendazole | 31431-39-7 | sc-204798 sc-204798A | 5 g 25 g | $46.00 $89.00 | 2 | |
Mebendazole also impacts tubulin polymerization. By changing the ciliary structure, GTL3's function can be indirectly inhibited. | ||||||
Griseofulvin | 126-07-8 | sc-202171A sc-202171 sc-202171B | 5 mg 25 mg 100 mg | $85.00 $220.00 $598.00 | 4 | |
Griseofulvin affects microtubule functions. Its impact can indirectly change the ciliary structure, inhibiting the proper function of GTL3. | ||||||
Latrunculin A, Latrunculia magnifica | 76343-93-6 | sc-202691 sc-202691B | 100 µg 500 µg | $265.00 $815.00 | 36 | |
Latrunculin A binds to actin monomers and prevents polymerization. By affecting the actin network supporting cilia, it can indirectly inhibit GTL3's function. | ||||||