Grx2 Activators
The indirect activators of Grx2 listed above are primarily antioxidants or compounds that enhance the cellular antioxidant capacity, reflecting Grx2's role in maintaining redox balance. N-Acetylcysteine (NAC) and GSH (Glutathione) directly contribute to the cellular pool of glutathione, the substrate for Grx2. By increasing glutathione availability, these compounds can potentially enhance the activity of Grx2 in reducing oxidative stress.
Alpha-Lipoic Acid, Vitamin C, and Vitamin E are well-known antioxidants that can scavenge reactive oxygen species (ROS) and improve the overall redox state of the cell. This improved redox environment could indirectly facilitate the function of Grx2. Curcumin, Resveratrol, Sulforaphane, and Quercetin are naturally occurring compounds with potent antioxidant properties. These compounds can modulate the cellular redox state, influencing the activity of redox-regulating enzymes like Grx2. Selenium compounds, such as Selenomethionine, are crucial for the activity of glutathione peroxidase, another key enzyme in the antioxidant defense system. The presence of selenium could complement the activity of Grx2 in maintaining redox homeostasis.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
N-Acetyl-L-cysteine | 616-91-1 | sc-202232 sc-202232A sc-202232C sc-202232B | 5 g 25 g 1 kg 100 g | $34.00 $74.00 $270.00 $114.00 | 34 | |
A precursor of glutathione, potentially enhancing the substrate availability for Grx2. | ||||||
Glutathione, reduced | 70-18-8 | sc-29094 sc-29094A | 10 g 1 kg | $82.00 $2091.00 | 8 | |
Directly increases glutathione levels, potentially modulating Grx2 activity. | ||||||
α-Lipoic Acid | 1077-28-7 | sc-202032 sc-202032A sc-202032B sc-202032C sc-202032D | 5 g 10 g 250 g 500 g 1 kg | $69.00 $122.00 $212.00 $380.00 $716.00 | 3 | |
Known for its antioxidant properties, can indirectly influence redox balance and Grx2 function. | ||||||
L-Selenomethionine | 3211-76-5 | sc-204050 sc-204050A | 250 mg 1 g | $223.00 $597.00 | 1 | |
Selenium is crucial for glutathione peroxidase activity, potentially complementing Grx2 function. | ||||||
L-Ascorbic acid, free acid | 50-81-7 | sc-202686 | 100 g | $46.00 | 5 | |
A well-known antioxidant, can modulate redox state and indirectly influence Grx2. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Exhibits antioxidant properties, potentially modulating the redox environment and Grx2 activity. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
A polyphenol with antioxidant effects, could influence redox balance and Grx2 function. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $153.00 $292.00 $489.00 $1325.00 $8465.00 $933.00 | 22 | |
Found in cruciferous vegetables, known for its antioxidant and cytoprotective properties, potentially affecting Grx2. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
A flavonoid with antioxidant properties, could modulate the redox state and influence Grx2. | ||||||
Zinc | 7440-66-6 | sc-213177 | 100 g | $48.00 | ||
An essential mineral that can influence antioxidant enzyme systems and potentially Grx2 activity. | ||||||