Date published: 2026-4-23

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GRP 78 Antibodies

Santa Cruz Biotechnology offers a broad range of GRP 78 monoclonal antibodies for investigating this essential protein's role in cellular processes. GRP 78 monoclonal antibodies are validated for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). GRP 78, also known as BiP, is a chaperone protein that plays a vital role in protein folding and quality control within the endoplasmic reticulum. GRP 78 is essential for cellular stress responses and is implicated in various diseases, including cancer and neurodegenerative disorders. The regulation of GRP 78 is crucial for maintaining cellular homeostasis and influencing cell survival under stress conditions. Understanding GRP 78's molecular mechanisms can provide significant insights into disease pathways and potential therapeutic targets. Investigating GRP 78's role in stress response pathways can reveal new perspectives on cellular adaptation and survival mechanisms. Santa Cruz Biotechnology monoclonal antibodies enable researchers to advance scientific understanding of GRP 78's role in health and disease, contributing to breakthrough discoveries in biomedical research.

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GRP 78 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

HSPA5/BiP/GRP78 Antibody (76-E6)

sc-13539rat IgGFL (m)WB, IPm, r, h
103
(25)

HSPA5/BiP/GRP78 Antibody (E-4)

sc-166490mouse IgG3 κ19-50 (h)WB, IP, IF, ELISAm, r, h
69
(3)

GRP 78 CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

HSPA5/BiP/GRP78 CRISPR/Cas9 KO Plasmid (h)

sc-400073hGene KnockoutGFP
2
(4)

HSPA5/BiP/GRP78 HDR Plasmid (h)

sc-400073-HDRhHomology Directed RepairPuromycin
2
(4)

HSPA5/BiP/GRP78 Double Nickase Plasmid (h)

sc-400073-NIChGene KnockoutPuromycin
2
(4)

HSPA5/BiP/GRP78 Double Nickase Plasmid (h2)

sc-400073-NIC-2hGene KnockoutPuromycin
2
(4)

HSPA5/BiP/GRP78 CRISPR/Cas9 KO Plasmid (m)

sc-420699mGene KnockoutGFP
1
(0)

HSPA5/BiP/GRP78 HDR Plasmid (m)

sc-420699-HDRmHomology Directed RepairPuromycin
1
(0)

HSPA5/BiP/GRP78 Double Nickase Plasmid (m)

sc-420699-NICmGene KnockoutPuromycin
1
(0)

GRP 78 CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

HSPA5/BiP/GRP78 CRISPR Activation Plasmid (h)

sc-400073-ACThGene ActivationPuro, Blast, Hygro
2
(4)

HSPA5/BiP/GRP78 Lentiviral Activation Particles (h)

sc-400073-LAChGene ActivationPuro, Blast, Hygro
2
(4)

HSPA5/BiP/GRP78 CRISPR Activation Plasmid (m)

sc-420699-ACTmGene ActivationPuro, Blast, Hygro
1
(0)

GRP 78 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

HSPA5/BiP/GRP78 siRNA (h)

sc-29338hGene SilencingN/A
47
(0)

HSPA5/BiP/GRP78 siRNA (h2)

sc-44261hGene SilencingN/A
2
(1)

HSPA5/BiP/GRP78 shRNA Plasmid (h)

sc-29338-SHhGene SilencingPuromycin
47
(0)

HSPA5/BiP/GRP78 shRNA Plasmid (h2)

sc-44261-SHhGene SilencingPuromycin
2
(1)

HSPA5/BiP/GRP78 shRNA (h) Lentiviral Particles

sc-29338-VhGene SilencingPuromycin
47
(0)

HSPA5/BiP/GRP78 shRNA (h2) Lentiviral Particles

sc-44261-VhGene SilencingPuromycin
2
(1)

HSPA5/BiP/GRP78 siRNA (m)

sc-35522mGene SilencingN/A
11
(2)

HSPA5/BiP/GRP78 siRNA (m2)

sc-44303mGene SilencingN/A
1
(0)

HSPA5/BiP/GRP78 shRNA Plasmid (m)

sc-35522-SHmGene SilencingPuromycin
11
(2)

HSPA5/BiP/GRP78 shRNA Plasmid (m2)

sc-44303-SHmGene SilencingPuromycin
1
(0)

HSPA5/BiP/GRP78 shRNA (m) Lentiviral Particles

sc-35522-VmGene SilencingPuromycin
11
(2)

HSPA5/BiP/GRP78 shRNA (m2) Lentiviral Particles

sc-44303-VmGene SilencingPuromycin
1
(0)