Date published: 2026-7-21

1-800-457-3801

SCBT Portrait Logo
Seach Input

GRK Antibodies

Santa Cruz Biotechnology supplies a comprehensive collection of GRK Antibodies for studying G protein-coupled receptor kinases (GRKs). GRK Antibodies are compatible with multiple research techniques, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). G protein-coupled receptor kinases play a crucial role in the regulation of cellular signaling pathways by phosphorylating activated G protein-coupled receptors, leading to their desensitization and internalization. This process is vital for maintaining cellular homeostasis and modulating responses to external stimuli. Understanding the function of GRKs is essential for elucidating their involvement in various physiological processes and their implications in diseases such as heart failure, cancer, and neurological disorders. GRK research continues to reveal new insights into cellular regulation mechanisms and potential therapeutic targets. Investigating GRK expression patterns helps researchers better understand their tissue distribution and functional significance. Studying GRK-mediated phosphorylation events provides valuable information about signal transduction pathways. Santa Cruz Biotechnology monoclonal antibodies for GRK research support scientists worldwide in advancing our understanding of cellular signaling mechanisms and disease development.

SEE ALSO...

GRK Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

GRK 1 Antibody (D11)

sc-56910mouse IgG1 κFL (h)WB, IP, IF, ELISAm, r, h

new

(2)

GRK 1 Antibody (G-8)

sc-8004mouse IgG1 κC-terminal (h)WB, IP, IF, ELISAm, r, h, bovine and avian
11
(7)

GRK 2 Antibody (C-9)

sc-13143mouse IgG2a κ468-689 (h)WB, IP, IF, ELISAm, r, h
58
(14)

GRK 2 Antibody (F-9)

sc-166284mouse IgG1 κ661-699 (h)WB, IP, IF, ELISAm, r, h
2
(6)

GRK 2 Antibody (E-7)

sc-166283mouse IgG2b κ661-689 (h)WB, IP, IF, ELISAm, r, h

new

(1)

GRK 2 Antibody (G-12)

sc-271359mouse IgG2a κ661-699 (h)WB, IP, IF, IHC(P), ELISAm, r, h

new

(2)

GRK 3 Antibody (C-11)

sc-365197mouse IgG1 κ646-688 (h)WB, IP, IF, ELISAm, r, h
3
(4)

GRK 4 Antibody (D-11)

sc-376891mouse IgG1 κ81-150 (h)WB, IP, IF, IHC(P), ELISAm, r, h

new

(2)

GRK 4 Antibody (A-5)

sc-9985mouse IgG1 κC-terminal (h)WB, IP, IF, IHC(P), ELISAm, r, h
3
(4)

GRK 5 Antibody (D-9)

sc-518005mouse IgG2a κ94-157 (h)WB, IP, IF, ELISAm, r, h
14
(3)

GRK 6 Antibody (D-10)

sc-377494mouse IgG1 κ96-165 (h)WB, IP, IF, ELISAh
1
(1)

GRK 6 Antibody (XX-4)

sc-100380mouse IgG2a κ71-170 (h)WB, IP, ELISAm, r, h
4
(5)

GRK 7 Antibody (C-2)

sc-398371mouse IgM κ472-501 (h)WB, IP, IF, ELISAh

new

(2)

GRK 7 Antibody (F-4)

sc-398660mouse IgG2b κ515-537 (h)WB, IP, IF, ELISAh

new

(1)

GRK siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

GRK 1 siRNA (h)

sc-29336hGene SilencingN/A0
(0)

GRK 1 shRNA Plasmid (h)

sc-29336-SHhGene SilencingPuromycin0
(0)

GRK 1 shRNA (h) Lentiviral Particles

sc-29336-VhGene SilencingPuromycin0
(0)

GRK 1 siRNA (h2)

sc-36208hGene SilencingN/A0
(0)

GRK 1 siRNA (m)

sc-35512mGene SilencingN/A0
(0)

GRK 1 shRNA Plasmid (h2)

sc-36208-SHhGene SilencingPuromycin0
(0)

GRK 1 shRNA Plasmid (m)

sc-35512-SHmGene SilencingPuromycin0
(0)

GRK 1 shRNA (h2) Lentiviral Particles

sc-36208-VhGene SilencingPuromycin0
(0)

GRK 1 shRNA (m) Lentiviral Particles

sc-35512-VmGene SilencingPuromycin0
(0)

GRK 2 siRNA (h)

sc-29337hGene SilencingN/A
13
(0)

GRK 2 shRNA Plasmid (h)

sc-29337-SHhGene SilencingPuromycin
13
(0)

GRK 2 shRNA (h) Lentiviral Particles

sc-29337-VhGene SilencingPuromycin
13
(0)

GRK 2 siRNA (m)

sc-35513mGene SilencingN/A
2
(0)

GRK 2 shRNA Plasmid (m)

sc-35513-SHmGene SilencingPuromycin
2
(0)

GRK 2 shRNA (m) Lentiviral Particles

sc-35513-VmGene SilencingPuromycin
2
(0)

GRK 2 siRNA (r)

sc-270408rGene SilencingN/A0
(0)

GRK 2 shRNA Plasmid (r)

sc-270408-SHrGene SilencingPuromycin0
(0)

GRK 2 shRNA (r) Lentiviral Particles

sc-270408-VrGene SilencingPuromycin0
(0)

GRK 3 siRNA (h)

sc-35514hGene SilencingN/A0
(0)

GRK 3 shRNA Plasmid (h)

sc-35514-SHhGene SilencingPuromycin0
(0)

GRK 3 shRNA (h) Lentiviral Particles

sc-35514-VhGene SilencingPuromycin0
(0)

GRK 3 siRNA (m)

sc-35515mGene SilencingN/A
1
(0)

GRK 3 shRNA Plasmid (m)

sc-35515-SHmGene SilencingPuromycin
1
(0)

GRK 3 shRNA (m) Lentiviral Particles

sc-35515-VmGene SilencingPuromycin
1
(0)

GRK 4 siRNA (h)

sc-35516hGene SilencingN/A0
(0)

GRK 4 shRNA Plasmid (h)

sc-35516-SHhGene SilencingPuromycin0
(0)

GRK 4 shRNA (h) Lentiviral Particles

sc-35516-VhGene SilencingPuromycin0
(0)

GRK 4 siRNA (m)

sc-35517mGene SilencingN/A0
(0)

GRK 4 shRNA Plasmid (m)

sc-35517-SHmGene SilencingPuromycin0
(0)

GRK 4 shRNA (m) Lentiviral Particles

sc-35517-VmGene SilencingPuromycin0
(0)

GRK 5 siRNA (h)

sc-39042hGene SilencingN/A
1
(0)

GRK 5 shRNA Plasmid (h)

sc-39042-SHhGene SilencingPuromycin
1
(0)

GRK 5 shRNA (h) Lentiviral Particles

sc-39042-VhGene SilencingPuromycin
1
(0)

GRK 5 siRNA (m)

sc-39043mGene SilencingN/A
1
(0)

GRK 5 shRNA Plasmid (m)

sc-39043-SHmGene SilencingPuromycin
1
(0)

GRK 5 shRNA (m) Lentiviral Particles

sc-39043-VmGene SilencingPuromycin
1
(0)

GRK 5 siRNA (r)

sc-270362rGene SilencingN/A
2
(0)

GRK 5 shRNA Plasmid (r)

sc-270362-SHrGene SilencingPuromycin
2
(0)

GRK 5 shRNA (r) Lentiviral Particles

sc-270362-VrGene SilencingPuromycin
2
(0)

GRK 6 siRNA (h)

sc-35518hGene SilencingN/A
1
(0)

GRK 6 shRNA Plasmid (h)

sc-35518-SHhGene SilencingPuromycin
1
(0)

GRK 6 shRNA (h) Lentiviral Particles

sc-35518-VhGene SilencingPuromycin
1
(0)

GRK 6 siRNA (m)

sc-35519mGene SilencingN/A0
(0)

GRK 6 shRNA Plasmid (m)

sc-35519-SHmGene SilencingPuromycin0
(0)

GRK 6 shRNA (m) Lentiviral Particles

sc-35519-VmGene SilencingPuromycin0
(0)

GRK 7 siRNA (h)

sc-60767hGene SilencingN/A0
(0)

GRK 7 shRNA Plasmid (h)

sc-60767-SHhGene SilencingPuromycin0
(0)

GRK 7 shRNA (h) Lentiviral Particles

sc-60767-VhGene SilencingPuromycin0
(0)

GRK CRISPR Knockout (KO) and HDR Plasmids

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

GRK 1 CRISPR/Cas9 KO Plasmid (h)

sc-406525Gene Knockouth0
(0)

GRK 2 CRISPR/Cas9 KO Plasmid (h)

sc-400558Gene Knockouth0
(0)

GRK 2 HDR Plasmid (h)

sc-400558-HDRHomology Directed Repairh0
(0)

GRK 2 CRISPR/Cas9 KO Plasmid (m)

sc-431016Gene Knockoutm0
(0)

GRK 2 HDR Plasmid (m)

sc-431016-HDRHomology Directed Repairm0
(0)

GRK 3 CRISPR/Cas9 KO Plasmid (h)

sc-403415Gene Knockouth0
(0)

GRK 3 HDR Plasmid (h)

sc-403415-HDRHomology Directed Repairh0
(0)

GRK 4 CRISPR/Cas9 KO Plasmid (h)

sc-402816Gene Knockouth0
(0)

GRK 5 CRISPR/Cas9 KO Plasmid (h)

sc-401285Gene Knockouth0
(0)

GRK 5 HDR Plasmid (h)

sc-401285-HDRHomology Directed Repairh0
(0)

GRK 6 CRISPR/Cas9 KO Plasmid (h)

sc-402061Gene Knockouth0
(0)

GRK 6 HDR Plasmid (h)

sc-402061-HDRHomology Directed Repairh0
(0)

GRK 6 CRISPR/Cas9 KO Plasmid (m)

sc-424026Gene Knockoutm0
(0)

GRK 6 HDR Plasmid (m)

sc-424026-HDRHomology Directed Repairm0
(0)

GRK CRISPR Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

GRK 2 Double Nickase Plasmid (h)

sc-400558-NICGene Knockouth0
(0)

GRK 2 Double Nickase Plasmid (h2)

sc-400558-NIC-2Gene Knockouth0
(0)

GRK 2 Double Nickase Plasmid (m)

sc-431016-NICGene Knockoutm0
(0)

GRK 2 Double Nickase Plasmid (m2)

sc-431016-NIC-2Gene Knockoutm0
(0)

GRK 3 Double Nickase Plasmid (h)

sc-403415-NICGene Knockouth0
(0)

GRK 3 Double Nickase Plasmid (h2)

sc-403415-NIC-2Gene Knockouth0
(0)

GRK 4 Double Nickase Plasmid (h)

sc-402816-NICGene Knockouth0
(0)

GRK 4 Double Nickase Plasmid (h2)

sc-402816-NIC-2Gene Knockouth0
(0)

GRK 5 Double Nickase Plasmid (h)

sc-401285-NICGene Knockouth0
(0)

GRK 5 Double Nickase Plasmid (h2)

sc-401285-NIC-2Gene Knockouth0
(0)

GRK 5 Double Nickase Plasmid (m)

sc-420661-NICGene Knockoutm0
(0)

GRK 6 Double Nickase Plasmid (h)

sc-402061-NICGene Knockouth0
(0)

GRK 6 Double Nickase Plasmid (h2)

sc-402061-NIC-2Gene Knockouth0
(0)

GRK CRISPR Activation Plasmids and Lentiviral Particles

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

GRK 2 CRISPR Activation Plasmid (h)

sc-400558-ACTGene Activationh0
(0)

GRK 3 CRISPR Activation Plasmid (h)

sc-403415-ACTGene Activationh0
(0)

GRK 4 CRISPR Activation Plasmid (h)

sc-402816-ACTGene Activationh0
(0)

GRK 4 CRISPR Activation Plasmid (h2)

sc-402816-ACT-2Gene Activationh0
(0)

GRK 5 CRISPR Activation Plasmid (h)

sc-401285-ACTGene Activationh0
(0)

GRK 5 CRISPR Activation Plasmid (h2)

sc-401285-ACT-2Gene Activationh0
(0)

GRK 6 CRISPR Activation Plasmid (h)

sc-402061-ACTGene Activationh0
(0)

GRK 6 CRISPR Activation Plasmid (h2)

sc-402061-ACT-2Gene Activationh0
(0)