GRK 4 Activators
Regarding the description of the chemical class called GRK 4 Activators, these compounds primarily function by modulating G protein-coupled receptor (GPCR) pathways. GPCRs are a large family of cell surface receptors that respond to a variety of external signals, leading to the activation of various intracellular signaling pathways. The chemicals listed influence GRK 4 activity by either directly interacting with GPCRs or by modifying the levels of secondary messengers like cAMP, which are crucial in GPCR signaling.
For example, compounds like Forskolin increase intracellular cAMP levels, enhancing PKA activity, which can subsequently influence GRK 4. Others, such as Isoproterenol and Epinephrine, act as agonists to specific GPCRs, initiating a cascade of G protein-mediated signaling events. This cascade can include the activation or modulation of GRK 4, either directly or through a series of interconnected signaling steps
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Activates adenylate cyclase, increasing cAMP levels and enhancing PKA activity, which indirectly influences GRK 4 activity through secondary messenger pathways. | ||||||
Isoproterenol Hydrochloride | 51-30-9 | sc-202188 sc-202188A | 100 mg 500 mg | $28.00 $38.00 | 5 | |
A β-adrenergic agonist stimulating GPCR pathways, leading to G protein activation and subsequent signaling cascades, potentially modulating GRK 4 activity. | ||||||
(−)-Epinephrine | 51-43-4 | sc-205674 sc-205674A sc-205674B sc-205674C sc-205674D | 1 g 5 g 10 g 100 g 1 kg | $41.00 $104.00 $201.00 $1774.00 $16500.00 | ||
Acts as a hormone and neurotransmitter, activating adrenergic receptors and triggering G protein-coupled signaling cascades that can influence GRK 4 activity. | ||||||
Dopamine | 51-61-6 | sc-507336 | 1 g | $290.00 | ||
Neurotransmitter that binds to GPCR receptors, initiating signal transduction pathways that modulate GRK 4 through G protein-mediated signaling pathways. | ||||||
Histamine, free base | 51-45-6 | sc-204000 sc-204000A sc-204000B | 1 g 5 g 25 g | $94.00 $283.00 $988.00 | 7 | |
Interacts with GPCR histamine receptors, leading to G protein-coupled intracellular signaling that can influence GRK 4 activity within the broader GPCR signaling network. | ||||||
L-Arginine | 74-79-3 | sc-391657B sc-391657 sc-391657A sc-391657C sc-391657D | 5 g 25 g 100 g 500 g 1 kg | $20.00 $31.00 $61.00 $219.00 $352.00 | 2 | |
Precursor for nitric oxide synthesis, potentially influencing GRK 4 activity through modulation of GPCR signaling pathways affected by nitric oxide. | ||||||
Serotonin hydrochloride | 153-98-0 | sc-201146 sc-201146A | 100 mg 1 g | $118.00 $187.00 | 15 | |
Binds to GPCR receptors, initiating a cascade of intracellular signaling influencing GRK 4 through G protein-mediated pathways activated by serotonin receptors. | ||||||
Adenosine | 58-61-7 | sc-291838 sc-291838A sc-291838B sc-291838C sc-291838D sc-291838E sc-291838F | 1 g 5 g 100 g 250 g 1 kg 5 kg 10 kg | $34.00 $48.00 $300.00 $572.00 $1040.00 $2601.00 $4682.00 | 1 | |
Interacts with GPCR receptors, affecting GRK 4 activity as part of the larger GPCR-mediated signaling network. | ||||||
Glucagon trifluoroacetic acid salt | 9007-92-5 (free base) | sc-495801 | 1 mg | $480.00 | ||
Activates G protein signaling pathways through its GPCR receptors, potentially modulating GRK 4 activity within these pathways. | ||||||
Angiotensin II, Human | 4474-91-3 | sc-363643 sc-363643A sc-363643B sc-363643C | 1 mg 5 mg 25 mg 100 mg | $51.00 $100.00 $310.00 $690.00 | 3 | |
Binds to its GPCR receptors, initiating signaling cascades that influence GRK 4 activity, potentially through G protein-mediated mechanisms. | ||||||