GRAMD4 Activators
GRAMD4 Activators refers to a group of chemicals that enhance the activity or expression of GRAMD4 through indirect interactions with various biochemical pathways. Chemicals such as Lithium Chloride and Forskolin engage signaling mechanisms that can lead to changes in gene expression patterns. Lithium, for example, can enhance the Wnt/β-catenin pathway, known for its role in gene transcription regulation, which could result in increased GRAMD4 expression. Forskolin and other cAMP-modulating agents like Rolipram and IBMX can activate protein kinase A (PKA), which may lead to the phosphorylation of transcription factors and subsequent upregulation of GRAMD4 expression.
On the other hand, compounds like Sodium Butyrate, SAHA, and Trichostatin A agents that can induce a more open chromatin structure, thereby facilitating the binding of transcriptional machinery to the promoter regions of genes, including GRAMD4, and driving their expression. Furthermore, chemicals that modulate signaling pathways and transcription factors, such as Retinoic Acid, Epigallocatechin Gallate, Curcumin, Resveratrol, and Sulforaphane, can lead to the transcriptional activation of GRAMD4 by influencing gene expression profiles within the cell.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Activates the Wnt/β-catenin signaling pathway, which may increase the expression of genes including GRAMD4. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Elevates cAMP levels, potentially enhancing PKA activity which could indirectly increase GRAMD4 expression by altering transcription. | ||||||
Rolipram | 61413-54-5 | sc-3563 sc-3563A | 5 mg 50 mg | $77.00 $216.00 | 18 | |
Phosphodiesterase inhibitor, raises cAMP levels potentially promoting GRAMD4 expression through PKA-mediated signaling pathways. | ||||||
IBMX | 28822-58-4 | sc-201188 sc-201188B sc-201188A | 200 mg 500 mg 1 g | $260.00 $350.00 $500.00 | 34 | |
Non-selective phosphodiesterase inhibitor, increases intracellular cAMP, which could upregulate GRAMD4 expression through PKA activation. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $31.00 $47.00 $84.00 $222.00 | 19 | |
Histone deacetylase inhibitor, may enhance GRAMD4 transcription by inducing a relaxed chromatin state. | ||||||
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $133.00 $275.00 | 37 | |
Another histone deacetylase inhibitor, potentially increases GRAMD4 expression by improving transcription factor access to DNA. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
Histone deacetylase inhibitor, could upregulate GRAMD4 by making chromatin more accessible for transcription. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Regulates gene expression through nuclear receptors, potentially affecting GRAMD4 expression. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
Influences gene expression and cellular signaling pathways, possibly affecting GRAMD4 expression. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Modulates multiple signaling pathways, possibly leading to upregulation of GRAMD4. | ||||||