Date published: 2025-10-14

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GPx-4 Antibodies

Santa Cruz Biotechnology features a diverse variety of GPx-4 monoclonal antibodies for research focused on understanding glutathione peroxidase 4. Multiple applications are supported, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Glutathione peroxidase 4 is a critical enzyme involved in cellular antioxidant defense, playing a vital role in protecting cells from oxidative stress and maintaining redox homeostasis. Its function is particularly important in regulating lipid peroxidation and preventing cellular damage, which is essential for normal cellular function and survival. Dysregulation of GPx-4 has been implicated in various diseases, including cancer and neurodegenerative disorders, highlighting its significance in both health and disease. GPx-4 monoclonal antibodies enable detailed investigation of oxidative stress mechanisms and their implications in various biological processes. Studying GPx-4 expression and activity patterns helps reveal new insights into disease pathways and potential therapeutic targets. The high specificity of GPx-4 monoclonal antibodies from Santa Cruz Biotechnology supports researchers worldwide in advancing our understanding of oxidative stress biology and disease mechanisms.

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GPx-4 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

Glutathione Peroxidase 4/GPX4 Antibody (E-12)

sc-166570mouse IgG2b κ108-197 (h)WB, IP, IF, IHC(P), ELISAm, r, h
84
(22)

Glutathione Peroxidase 4/GPX4 Antibody (B-12)

sc-166120mouse IgG1 κ108-197 (h)WB, IP, IF, ELISAm, r, h
18
(5)

Glutathione Peroxidase 4/GPX4 Antibody (D-3)

sc-166437mouse IgG2a κ108-197 (h)WB, IP, IF, ELISAm, r, h
2
(1)

GPx-4 CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Glutathione Peroxidase 4/GPX4 CRISPR/Cas9 KO Plasmid (h)

sc-401558hGene KnockoutGFP
1
(0)

Glutathione Peroxidase 4/GPX4 HDR Plasmid (h)

sc-401558-HDRhHomology Directed RepairPuromycin
1
(0)

Glutathione Peroxidase 4/GPX4 Double Nickase Plasmid (h)

sc-401558-NIChGene KnockoutPuromycin
1
(0)

Glutathione Peroxidase 4/GPX4 Double Nickase Plasmid (h2)

sc-401558-NIC-2hGene KnockoutPuromycin
1
(0)

Glutathione Peroxidase 4/GPX4 CRISPR/Cas9 KO Plasmid (m)

sc-436949mGene KnockoutGFP
1
(0)

Glutathione Peroxidase 4/GPX4 HDR Plasmid (m)

sc-436949-HDRmHomology Directed RepairPuromycin
1
(0)

Glutathione Peroxidase 4/GPX4 Double Nickase Plasmid (m)

sc-436949-NICmGene KnockoutPuromycin
1
(0)

Glutathione Peroxidase 4/GPX4 Double Nickase Plasmid (m2)

sc-436949-NIC-2mGene KnockoutPuromycin
1
(0)

GPx-4 CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Glutathione Peroxidase 4/GPX4 CRISPR Activation Plasmid (h)

sc-401558-ACThGene ActivationPuro, Blast, Hygro
1
(0)

Glutathione Peroxidase 4/GPX4 CRISPR Activation Plasmid (h2)

sc-401558-ACT-2hGene ActivationPuro, Blast, Hygro
1
(0)

Glutathione Peroxidase 4/GPX4 Lentiviral Activation Particles (h)

sc-401558-LAChGene ActivationPuro, Blast, Hygro
1
(0)

Glutathione Peroxidase 4/GPX4 Lentiviral Activation Particles (h2)

sc-401558-LAC-2hGene ActivationPuro, Blast, Hygro
1
(0)

Glutathione Peroxidase 4/GPX4 CRISPR Activation Plasmid (m)

sc-436949-ACTmGene ActivationPuro, Blast, Hygro
1
(0)

Glutathione Peroxidase 4/GPX4 CRISPR Activation Plasmid (m2)

sc-436949-ACT-2mGene ActivationPuro, Blast, Hygro
1
(0)

Glutathione Peroxidase 4/GPX4 Lentiviral Activation Particles (m)

sc-436949-LACmGene ActivationPuro, Blast, Hygro
1
(0)

Glutathione Peroxidase 4/GPX4 Lentiviral Activation Particles (m2)

sc-436949-LAC-2mGene ActivationPuro, Blast, Hygro
1
(0)

GPx-4 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Glutathione Peroxidase 4/GPX4 siRNA (h)

sc-44465hGene SilencingN/A
2
(0)

Glutathione Peroxidase 4/GPX4 shRNA Plasmid (h)

sc-44465-SHhGene SilencingPuromycin
2
(0)

Glutathione Peroxidase 4/GPX4 shRNA (h) Lentiviral Particles

sc-44465-VhGene SilencingPuromycin
2
(0)

Glutathione Peroxidase 4/GPX4 siRNA (m)

sc-63302mGene SilencingN/A
1
(0)

Glutathione Peroxidase 4/GPX4 shRNA Plasmid (m)

sc-63302-SHmGene SilencingPuromycin
1
(0)

Glutathione Peroxidase 4/GPX4 shRNA (m) Lentiviral Particles

sc-63302-VmGene SilencingPuromycin
1
(0)