GPSN2 Inhibitors
The chemicals described in the context of GPSN2 inhibitors predominantly influence the function of GPSN2 indirectly, by modulating G protein-coupled receptor (GPCR) signaling. Given that GPSN2 is implicated in GPCR pathways, affecting these receptors can have downstream consequences on GPSN2's activity. For instance, compounds like Propranolol, a non-selective beta-adrenergic receptor antagonist, and Losartan, an angiotensin II receptor antagonist, bind to their respective receptors, thereby potentially altering the signaling cascade and the function of GPSN2 as a pathway modulator.
Moreover, the diverse array of GPCRs and their ligands underscores the potential complexity in GPSN2's regulatory function. Clozapine and Risperidone are atypical antipsychotics that affect multiple GPCRs, illustrating how polypharmacology can bring about multi-faceted modulation of GPCR-mediated pathways. Similarly, Loratadine and Cimetidine, antagonists for different histamine receptors, demonstrate the breadth of compounds that can impinge on GPCR signaling and, by extension, GPSN2 activity.
SEE ALSO...
Items 1 to 10 of 11 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $74.00 $243.00 $731.00 $2572.00 $21848.00 | 53 | |
Binds to DNA, preventing RNA synthesis. By inhibiting RNA synthesis, can influence REXO1's role in rRNA processing. | ||||||
α-Amanitin | 23109-05-9 | sc-202440 sc-202440A | 1 mg 5 mg | $269.00 $1050.00 | 26 | |
Inhibitor of RNA polymerase II, potentially impacting RNA processing and subsequently REXO1's function. | ||||||
Cordycepin | 73-03-0 | sc-203902 | 10 mg | $101.00 | 5 | |
Adenosine analog that inhibits RNA synthesis, thereby potentially influencing REXO1. | ||||||
Doxorubicin | 23214-92-8 | sc-280681 sc-280681A | 1 mg 5 mg | $176.00 $426.00 | 43 | |
Intercalates into DNA, disrupting DNA processing which might indirectly impact REXO1's function. | ||||||
Etoposide (VP-16) | 33419-42-0 | sc-3512B sc-3512 sc-3512A | 10 mg 100 mg 500 mg | $51.00 $231.00 $523.00 | 63 | |
Inhibits DNA topoisomerase II, possibly affecting DNA processing, indirectly modulating REXO1's role. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
DNA methyltransferase inhibitor which might have implications on DNA processing and REXO1's function. | ||||||
DRB | 53-85-0 | sc-200581 sc-200581A sc-200581B sc-200581C | 10 mg 50 mg 100 mg 250 mg | $43.00 $189.00 $316.00 $663.00 | 6 | |
Inhibits RNA polymerase II elongation, potentially affecting RNA processing and indirectly REXO1. | ||||||
Cisplatin | 15663-27-1 | sc-200896 sc-200896A | 100 mg 500 mg | $138.00 $380.00 | 101 | |
DNA cross-linking agent, which can impact DNA processing and subsequently the function of REXO1. | ||||||
Aphidicolin | 38966-21-1 | sc-201535 sc-201535A sc-201535B | 1 mg 5 mg 25 mg | $84.00 $306.00 $1104.00 | 30 | |
Inhibits DNA polymerase α, δ, and ε, thereby potentially influencing REXO1's function. | ||||||
Fludarabine | 21679-14-1 | sc-204755 sc-204755A | 5 mg 25 mg | $58.00 $204.00 | 15 | |
Purine analog that inhibits DNA synthesis, potentially affecting REXO1's role in rDNA processing. | ||||||