Date published: 2025-12-24

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GPR97 Inhibitors

GPR97 Inhibitors constitute a specific class of chemical compounds designed to target and modulate the activity of GPR97, which stands for G protein-coupled receptor 97. GPR97 belongs to the G protein-coupled receptor (GPCR) family, a vast group of cell surface receptors that play critical roles in transmitting signals from the extracellular environment to the inside of cells. GPR97 itself is a relatively newly discovered member of this family, and its precise functions and signaling pathways are areas of ongoing research. Inhibitors of GPR97 are developed to interact with this receptor, influencing its binding to ligands, downstream signaling events, cellular localization, or other processes associated with GPR97 function. Structurally, GPR97 inhibitors are designed with the aim of engaging specific regions or binding sites on the GPR97 receptor. This interaction may interfere with the receptor's normal functioning, affecting its ability to bind to ligands, initiate intracellular signaling cascades, or participate in cellular processes where GPR97 is involved. The mechanisms by which GPR97 inhibitors exert their effects can vary, but their primary role is to serve as valuable research tools, enabling scientists to probe the roles and functions of GPR97 in various biological contexts.
Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Suramin sodium

129-46-4sc-507209
sc-507209F
sc-507209A
sc-507209B
sc-507209C
sc-507209D
sc-507209E
50 mg
100 mg
250 mg
1 g
10 g
25 g
50 g
$149.00
$210.00
$714.00
$2550.00
$10750.00
$21410.00
$40290.00
5
(1)

Suramin is a polysulfonated naphthylurea that inhibits various GPCRs.

NF449

627034-85-9sc-478179
sc-478179A
sc-478179B
10 mg
25 mg
100 mg
$199.00
$460.00
$1479.00
1
(0)

It is a Gαs-selective GPCR antagonist, and could affect receptors coupling to this protein.

YM 254890

568580-02-9sc-507356
1 mg
$500.00
(0)

This compound inhibits Gq signaling downstream of GPCRs.

SQ 22536

17318-31-9sc-201572
sc-201572A
5 mg
25 mg
$93.00
$356.00
13
(1)

It's an adenylate cyclase inhibitor, affecting some GPCR signaling pathways.

KT 5720

108068-98-0sc-3538
sc-3538A
sc-3538B
50 µg
100 µg
500 µg
$97.00
$144.00
$648.00
47
(2)

A PKA inhibitor which might impact signaling from certain GPCRs.

Gö 6976

136194-77-9sc-221684
500 µg
$223.00
8
(1)

Known to inhibit protein kinase C which is sometimes activated by GPCRs.

LY 294002

154447-36-6sc-201426
sc-201426A
5 mg
25 mg
$121.00
$392.00
148
(1)

A PI3K inhibitor that can affect GPCR signaling.

Genistein

446-72-0sc-3515
sc-3515A
sc-3515B
sc-3515C
sc-3515D
sc-3515E
sc-3515F
100 mg
500 mg
1 g
5 g
10 g
25 g
100 g
$26.00
$92.00
$120.00
$310.00
$500.00
$908.00
$1821.00
46
(1)

It's a tyrosine kinase inhibitor, which might have an effect on certain GPCR pathways.