GPR110 Activators
GPR110, also known as ADGRF1, is part of the adhesion G protein-coupled receptor (GPCR) family, which is a large and diverse group of proteins responsible for a wide range of cellular signaling processes. The GPCR family is characterized by their seven-transmembrane structure and their ability to interact with G proteins, triggering intracellular responses upon ligand binding. GPR110 activators are chemical compounds that interact with the GPR110 protein, binding to it and initiating a cascade of intracellular events.
The structure of GPR110 activators is likely to be diverse, given the broad range of molecules that can act as GPCR ligands. Generally, these molecules will have structural features that allow them to interact with the GPR110 protein, and these interactions will trigger a conformational change in the protein, leading to its activation. The specific nature of these interactions likely varies depending on the particular activator in question. Some GPR110 activators might bind directly to the GPR110 protein, while others may interact indirectly, for example, by binding to a different site on the protein, which then induces a change in the GPR110's conformation.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Activates adenylyl cyclase, which increases cAMP levels in cells. Since some GPCRs, potentially including GPR110, act through cAMP-mediated pathways, forskolin might have an indirect influence on GPR110 activity. | ||||||
Isoproterenol Hydrochloride | 51-30-9 | sc-202188 sc-202188A | 100 mg 500 mg | $28.00 $38.00 | 5 | |
Acts as a non-selective beta-adrenergic agonist. By activating GPCRs in the beta-adrenergic family, it could potentially affect signaling pathways that indirectly influence GPR110. | ||||||
Pertussis Toxin (islet-activating protein) | 70323-44-3 | sc-200837 | 50 µg | $451.00 | 3 | |
Blocks the activity of Gi/o type G proteins, which could affect the signaling of some GPCRs and potentially alter the cellular environment in a way that influences GPR110. | ||||||
Carbachol | 51-83-2 | sc-202092 sc-202092A sc-202092C sc-202092D sc-202092B sc-202092E | 1 g 10 g 25 g 50 g 100 g 250 g | $122.00 $281.00 $388.00 $683.00 $1428.00 $3060.00 | 12 | |
Acts as a cholinergic agonist that activates muscarinic acetylcholine receptors. By modulating the activity of these GPCRs, it might indirectly influence GPR110. | ||||||
Atropine | 51-55-8 | sc-252392 | 5 g | $204.00 | 2 | |
Acts as a muscarinic antagonist that inhibits activity at muscarinic acetylcholine receptors. By blocking these GPCRs, it could potentially affect pathways that indirectly influence GPR110. | ||||||
(−)-Epinephrine | 51-43-4 | sc-205674 sc-205674A sc-205674B sc-205674C sc-205674D | 1 g 5 g 10 g 100 g 1 kg | $41.00 $104.00 $201.00 $1774.00 $16500.00 | ||
Acts as a hormone that can activate alpha and beta-adrenergic receptors. This could potentially affect signaling pathways that indirectly influence GPR110. | ||||||
L-Noradrenaline | 51-41-2 | sc-357366 sc-357366A | 1 g 5 g | $326.00 $485.00 | 3 | |
Acts as a neurotransmitter and hormone, an agonist for adrenergic receptors. By influencing these GPCRs, it might have an indirect influence on GPR110. | ||||||
Alprenolol hydrochloride | 13707-88-5 | sc-203503 sc-203503A sc-203503B sc-203503C | 50 mg 100 mg 200 mg 500 mg | $117.00 $197.00 $306.00 $682.00 | 2 | |
Acts as a non-selective beta-adrenergic antagonist. By blocking the activation of GPCRs in the beta-adrenergic family, it could potentially affect pathways that indirectly influence GPR110. | ||||||
Labetalol | 36894-69-6 | sc-484723 | 50 mg | $180.00 | ||
Acts as a mixed alpha/beta adrenergic antagonist. By blocking the activation of GPCRs in the alpha and beta-adrenergic families, it could potentially affect pathways that indirectly influence GPR110. | ||||||