Molecular structure of Atropine, CAS Number: 51-55-8
Atropine (CAS 51-55-8)
See product citations (2)
Alternate Names:
Hyoscyamine; Atropen
Application:
Atropine is a competitive antagonist of mAChR M (muscarinic acetylcholine receptors)
CAS Number:
51-55-8
Purity:
≥98%
Molecular Weight:
289.37
Molecular Formula:
C17H23NO3
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Atropine is a naturally occurring alkaloid found in various plants of the Solanaceae family, such as belladonna and jimsonweed. It is a chiral molecule, existing as two enantiomers that are mirror images of each other. In scientific contexts, atropine is extensively used to explore the pharmacology of muscarinic receptors, which play a significant role in regulating bodily functions like smooth muscle contraction and heart rate. Researchers employ atropine to investigate the influence of anticholinergic substances on both the central and autonomic nervous systems, as well as their effects on the gastrointestinal, cardiovascular, and respiratory systems. Atropine functions by inhibiting the binding of acetylcholine to muscarinic receptors, thereby impeding parasympathetic nervous system activities.
Atropine (CAS 51-55-8) References
- Pralidoxime in carbaryl poisoning: an animal model. | Mercurio-Zappala, M., et al. 2007. Hum Exp Toxicol. 26: 125-9. PMID: 17370870
- Zebrafish based assays for the assessment of cardiac, visual and gut function--potential safety screens for early drug discovery. | Berghmans, S., et al. 2008. J Pharmacol Toxicol Methods. 58: 59-68. PMID: 18585469
- An update on the genotoxicity and carcinogenicity of marketed pharmaceuticals with reference to in silico predictivity. | Snyder, RD. 2009. Environ Mol Mutagen. 50: 435-50. PMID: 19334052
- pKa and solubility of drugs in water, ethanol, and 1-octanol. | Domańska, U., et al. 2009. J Phys Chem B. 113: 8941-7. PMID: 19518053
- Simultaneous quantification of atropine and scopolamine in infusions of herbal tea and Solanaceae plant material by matrix-assisted laser desorption/ionization time-of-flight (tandem) mass spectrometry. | John, H., et al. 2018. Rapid Commun Mass Spectrom. 32: 1911-1921. PMID: 30117208
- Atropine reduces aldicarb-induced sensitivity to C. elegans electroshock model. | Suthakaran, N., et al. 2022. MicroPubl Biol. 2022: PMID: 36017190
- A comparison of the oximes HS-6 and HI-6 in the therapy of soman intoxication in rodents. | Kepner, LA. and Wolthuis, OL. 1978. Eur J Pharmacol. 48: 377-82. PMID: 648582
- Liquid and poly(vinyl chloride) atropine-reineckate membrane electrodes for determination of atropine. | Hassan, SS. and Tadros, FS. 1984. Anal Chem. 56: 542-6. PMID: 6711823
- The dependence of the blood level of the oxime HS-6 on the severity of organophosphate poisoning. | Wolthuis, OL., et al. 1976. Eur J Pharmacol. 39: 417-21. PMID: 976329
- Tropane alkaloids (hyoscyamine, scopolamine and atropine) from genus Datura: extractions, contents, syntheses and effects | Z Shi, W Zou, Z Zhu, Z Xiong, S Li, P Dong. 2022. Industrial Crops and Products. 186: 115283.
- Atropine and scopolamine occurrence in spices and fennel infusions | L González-Gómez, J Gañán, S Morante-Zarcero. 2023. Food Control. 146: 109555.
Inhibitor of:
4930544G11Rik, ABHD5, AChR, AChRβ3, CTRB2, D-GPCR, E3BP, EG433107, EG666827, GPR158, GPR171, GPR178, HMW-Guanylin, mAChR M, mAChR M1, mAChR M2, mAChR M3, mAChR M5, motilin, NRAGE, Olfr1, Olfr1012, Olfr1032, Olfr1049, Olfr1056, Olfr1087, Olfr1100, Olfr151, Olfr224, Olfr265, Olfr31, Olfr373, Olfr393, Olfr47, Olfr472, Olfr474, Olfr507, Olfr564, Olfr723, Olfr739, Olfr799, Olfr823, Olfr851, Olfr881, Olfr901, Olfr902, Olfr907, Olfr936, Olr1076, Olr1096, Olr1104, Olr1228, Olr1425, Olr1431, Olr1433, Olr1488, Olr1519, Olr1520, Olr1545, Olr1546, Olr1547, Olr1559, Olr1567, Olr1569, Olr158, Olr1593, Olr1602, Olr1639, Olr1640, Olr1664, Olr226, Olr23, Olr25, Olr3, Olr336, Olr34, Olr358, Olr404, Olr552, Olr657, Olr709, Olr713, Olr747, Olr792, Olr804, Olr840, Olr905, OR5K1, Peptide YY3, PLRP3, R7BP, secretin, SMGC, Tracheobronchial Mucin, V1RA1, V1RB7, V1RI2, Vmn1r113, Vmn1r158, Vmn1r161, Vmn2r100, Vmn2r103, Vmn2r2, Vmn2r35, Vmn2r45, Vmn2r49, Vmn2r55, Vmn2r56, Vmn2r59, Vmn2r68, Vmn2r69, Vmn2r77, Vmn2r81, Vmn2r83, and Vmn2r90.Activator of:
ACTG2, GASP-1, GPR110, GPR111, GPR114, GPR115, KLHL12, KLHL34, RGS9, and sGC α1.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Atropine, 5 g | sc-252392 | 5 g | $204.00 |