Date published: 2025-12-3

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Alprenolol hydrochloride (CAS 13707-88-5)

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Alternate Names:
Alprenolol hydrochloride is also known as 1-(o-Allylphenoxy)-3-(isopropylamino)-2-propanol hydrochloride.
Application:
Alprenolol hydrochloride is a non-selective β-adrenoceptor and SR-1A (5HTR1A) inhibitor used in the treatment of angina pectoris.
CAS Number:
13707-88-5
Purity:
≥95%
Molecular Weight:
285.81
Molecular Formula:
C15H23NO2•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Alprenolol hydrochloride serves as an antagonist primarily to β-adrenoceptors, with a higher affinity for β2 over β1 and β3 subtypes, and it also interacts with 5-HT1A receptors. This compound effectively blocks these receptors, which are for various physiological responses. By inhibiting β1 and β2-adrenoceptors, Alprenolol hydrochloride modulates the effects of endogenous catecholamines such as adrenaline and noradrenaline, which are naturally occurring compounds that play a role in the body′s fight-or-flight response. This blockade can alter cellular signaling pathways, leading to varied biochemical and physiological outcomes. In research applications, the use of Alprenolol hydrochloride allows scientists to study the role of these receptors in different systems and processes, aiding in the understanding of their underlying mechanisms and effects in various biological applications. Additionally, its interaction with 5-HT1A receptors, which are involved in serotonin signaling, provides further opportunities to explore the complexities of neurotransmitter systems and their implications in modulating mood and cognitive functions.


Alprenolol hydrochloride (CAS 13707-88-5) References

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  7. Sweeping-micellar electrokinetic chromatography for the simultaneous analysis of tricyclic antidepressant and β-blocker drugs in wastewater.  |  Aranas, AT., et al. 2011. Talanta. 85: 86-90. PMID: 21645674
  8. Stressors impair odor recognition memory via an olfactory bulb-dependent noradrenergic mechanism.  |  Manella, LC., et al. 2013. Front Integr Neurosci. 7: 97. PMID: 24391558
  9. Fast simultaneous LC/MS/MS determination of 10 active compounds in human serum for therapeutic drug monitoring in psychiatric medication.  |  Sistik, P., et al. 2016. Biomed Chromatogr. 30: 217-24. PMID: 26094602
  10. Allosteric regulation of G protein-coupled receptor activity by phospholipids.  |  Dawaliby, R., et al. 2016. Nat Chem Biol. 12: 35-9. PMID: 26571351
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Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Alprenolol hydrochloride, 50 mg

sc-203503
50 mg
$115.00

Alprenolol hydrochloride, 100 mg

sc-203503A
100 mg
$193.00

Alprenolol hydrochloride, 200 mg

sc-203503B
200 mg
$300.00

Alprenolol hydrochloride, 500 mg

sc-203503C
500 mg
$669.00