GP49B inhibitors refers to agents that can interfere with the inhibitory signals mediated by GP49B. This interference can occur through several mechanisms, such as blocking the protein's ability to bind to its ligands, altering the downstream signaling pathways it controls, or modulating the immune environment in which GP49B operates.
The listed compounds can affect these processes through distinct biochemical interactions, ranging from direct blockade of protein-protein interactions to broader immunomodulatory effects that ultimately impact the function of GP49B. It is important to note that these compounds are not specific GP49B inhibitors; instead, they are agents known to modulate immune responses in a way that could indirectly influence the function of GP49B. These effects would contribute to the complex regulation of immune cell signaling and activity, rather than providing targeted inhibition of GP49B.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Zinc | 7440-66-6 | sc-213177 | 100 g | $48.00 | ||
A competitive inhibitor of heme oxygenase-1 (HO-1) that may enhance immune responses, indirectly affecting GP49B/LILRB4. | ||||||
Chloroquine | 54-05-7 | sc-507304 | 250 mg | $69.00 | 2 | |
An antimalarial drug that also has immunomodulatory effects, which might influence the signaling pathways involving GP49B/LILRB4. | ||||||
Imatinib | 152459-95-5 | sc-267106 sc-267106A sc-267106B | 10 mg 100 mg 1 g | $26.00 $119.00 $213.00 | 27 | |
A tyrosine kinase inhibitor known to have immunomodulatory effects, which could indirectly affect GP49B/LILRB4 function. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
A compound from turmeric with anti-inflammatory properties that could modulate immune responses, potentially impacting GP49B/LILRB4. | ||||||
Cyclosporin A | 59865-13-3 | sc-3503 sc-3503-CW sc-3503A sc-3503B sc-3503C sc-3503D | 100 mg 100 mg 500 mg 10 g 25 g 100 g | $63.00 $92.00 $250.00 $485.00 $1035.00 $2141.00 | 69 | |
An immunosuppressant that can also affect signaling pathways, potentially altering the function of inhibitory receptors like GP49B/LILRB4. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
A stilbenoid with anti-inflammatory and antioxidant properties that could indirectly affect immune receptor signaling. | ||||||
Lenalidomide | 191732-72-6 | sc-218656 sc-218656A sc-218656B | 10 mg 100 mg 1 g | $50.00 $374.00 $2071.00 | 18 | |
An immunomodulatory drug that can enhance T cell and NK cell responses, possibly impacting the inhibitory role of GP49B/LILRB4. | ||||||