GON4L Activators
GON4L, involved in transcriptional regulation and chromatin remodeling, plays a critical role in gene expression modulation. The functional activity of GON4L can be enhanced by compounds that influence chromatin structure and epigenetic mechanisms. Histone deacetylase inhibitors such as Sodium Butyrate, Valproic Acid, and Nicotinamide act by increasing chromatin accessibility, potentially enhancing GON4L's ability to regulate transcription. These compounds promote a more open chromatin structure, facilitating GON4L's interaction with DNA and its subsequent role in modulating gene expression.
Other compounds like 5-Azacytidine and S-Adenosylmethionine, which affect DNA methylation patterns, can indirectly influence the transcriptional regulatory functions of GON4L. Alterations in DNA methylation can lead to changes in gene expression profiles, where GON4L might play a significant role. Additionally, signaling molecules such as Retinoic Acid and β-Estradiol, known to modulate gene expression, may also enhance GON4L's regulatory functions in specific gene networks. Phytoestrogens like Genistein and flavonoids like Epigallocatechin Gallate (EGCG) can modulate epigenetic markers and potentially influence GON4L-mediated transcriptional regulation.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
A DNA methyltransferase inhibitor, altering DNA methylation status and potentially enhancing GON4L activity in gene expression regulation. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $31.00 $47.00 $84.00 $222.00 | 19 | |
A histone deacetylase inhibitor, can enhance GON4L function by increasing chromatin accessibility. | ||||||
Valproic Acid | 99-66-1 | sc-213144 | 10 g | $87.00 | 9 | |
Modulates histone deacetylase activity, potentially influencing GON4L's role in transcription regulation. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Influences gene expression, potentially enhancing GON4L's function in transcriptional regulation. | ||||||
β-Estradiol | 50-28-2 | sc-204431 sc-204431A | 500 mg 5 g | $63.00 $182.00 | 8 | |
Can modulate gene expression, possibly enhancing GON4L activity in estrogen-responsive gene regulation. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $45.00 $164.00 $200.00 $402.00 $575.00 $981.00 $2031.00 | 46 | |
A phytoestrogen known to influence gene expression, potentially affecting GON4L-mediated transcriptional regulation. | ||||||
Ademetionine | 29908-03-0 | sc-278677 sc-278677A | 100 mg 1 g | $184.00 $668.00 | 2 | |
A methyl donor for DNA methylation, indirectly affecting GON4L function in gene regulation. | ||||||
Mithramycin A | 18378-89-7 | sc-200909 | 1 mg | $55.00 | 6 | |
Binds to DNA and influences transcription, potentially affecting GON4L-mediated gene expression. | ||||||
Nicotinamide | 98-92-0 | sc-208096 sc-208096A sc-208096B sc-208096C | 100 g 250 g 1 kg 5 kg | $44.00 $66.00 $204.00 $831.00 | 6 | |
An inhibitor of sirtuins, a class of histone deacetylases, potentially enhancing GON4L's transcriptional activity. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
Influences epigenetic mechanisms, potentially modulating GON4L's role in chromatin remodeling and gene regulation. | ||||||