Date published: 2026-4-1

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GMEB-2 Inhibitors

GMEB-2 inhibitors represent a specialized chemical class of compounds meticulously designed to interact with and modulate the activity of Glucocorticoid Modulatory Element-Binding Protein 2 (GMEB-2). GMEB-2 is a protein that plays a vital role in gene regulation, particularly in the context of modulating the activity of specific DNA sequences known as glucocorticoid modulatory elements (GMEs). These elements are found within the regulatory regions of certain genes, and GMEB-2 is involved in binding to them, thus influencing the gene's expression. Inhibitors targeting GMEB-2 are developed with precision to selectively interact with this protein, allowing researchers to explore the nuances of its role in gene expression and DNA regulation.

The selectivity of GMEB-2 inhibitors is crucial for scientific investigations, as it enables researchers to investigate the specific functions and regulatory mechanisms governed by GMEB-2 without affecting the broader cellular processes. By utilizing GMEB-2 inhibitors, researchers can delve deeper into the molecular and genetic mechanisms associated with this protein's role, providing insights into the precise pathways and interactions that underlie gene expression and DNA modulation. This knowledge not only enhances our understanding of fundamental cellular biology but also has the potential for broader implications, offering insights into the intricate world of gene regulation, transcription, and the molecular underpinnings of biological processes.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Triptolide

38748-32-2sc-200122
sc-200122A
1 mg
5 mg
$90.00
$204.00
13
(1)

Inhibits RNA polymerase II, leading to reduced transcription.

Actinomycin D

50-76-0sc-200906
sc-200906A
sc-200906B
sc-200906C
sc-200906D
5 mg
25 mg
100 mg
1 g
10 g
$74.00
$243.00
$731.00
$2572.00
$21848.00
53
(3)

Binds to DNA and prevents transcription by RNA polymerase.

α-Amanitin

23109-05-9sc-202440
sc-202440A
1 mg
5 mg
$269.00
$1050.00
26
(2)

Blocks RNA polymerase II, halting mRNA synthesis.

Mycophenolic acid

24280-93-1sc-200110
sc-200110A
100 mg
500 mg
$69.00
$266.00
8
(1)

Inhibits inosine monophosphate dehydrogenase, reducing GTP.

Flavopiridol

146426-40-6sc-202157
sc-202157A
5 mg
25 mg
$78.00
$259.00
41
(3)

CDK inhibitor that disrupts cell cycle and transcription.

DRB

53-85-0sc-200581
sc-200581A
sc-200581B
sc-200581C
10 mg
50 mg
100 mg
250 mg
$43.00
$189.00
$316.00
$663.00
6
(1)

Inhibits RNA polymerase II elongation.

Thiolutin

87-11-6sc-200387
sc-200387A
1 mg
5 mg
$101.00
$406.00
1
(2)

RNA polymerase inhibitor, disrupting transcription.

C646

328968-36-1sc-364452
sc-364452A
10 mg
50 mg
$265.00
$944.00
5
(1)

Selective inhibitor of histone acetyltransferase p300.

CX-5461

1138549-36-6sc-507275
5 mg
$245.00
(0)

Disrupts RNA polymerase I transcription of ribosomal RNA.