GMEB-2 inhibitors represent a specialized chemical class of compounds meticulously designed to interact with and modulate the activity of Glucocorticoid Modulatory Element-Binding Protein 2 (GMEB-2). GMEB-2 is a protein that plays a vital role in gene regulation, particularly in the context of modulating the activity of specific DNA sequences known as glucocorticoid modulatory elements (GMEs). These elements are found within the regulatory regions of certain genes, and GMEB-2 is involved in binding to them, thus influencing the gene's expression. Inhibitors targeting GMEB-2 are developed with precision to selectively interact with this protein, allowing researchers to explore the nuances of its role in gene expression and DNA regulation.
The selectivity of GMEB-2 inhibitors is crucial for scientific investigations, as it enables researchers to investigate the specific functions and regulatory mechanisms governed by GMEB-2 without affecting the broader cellular processes. By utilizing GMEB-2 inhibitors, researchers can delve deeper into the molecular and genetic mechanisms associated with this protein's role, providing insights into the precise pathways and interactions that underlie gene expression and DNA modulation. This knowledge not only enhances our understanding of fundamental cellular biology but also has the potential for broader implications, offering insights into the intricate world of gene regulation, transcription, and the molecular underpinnings of biological processes.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Triptolide | 38748-32-2 | sc-200122 sc-200122A | 1 mg 5 mg | $90.00 $204.00 | 13 | |
Inhibits RNA polymerase II, leading to reduced transcription. | ||||||
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $74.00 $243.00 $731.00 $2572.00 $21848.00 | 53 | |
Binds to DNA and prevents transcription by RNA polymerase. | ||||||
α-Amanitin | 23109-05-9 | sc-202440 sc-202440A | 1 mg 5 mg | $269.00 $1050.00 | 26 | |
Blocks RNA polymerase II, halting mRNA synthesis. | ||||||
Mycophenolic acid | 24280-93-1 | sc-200110 sc-200110A | 100 mg 500 mg | $69.00 $266.00 | 8 | |
Inhibits inosine monophosphate dehydrogenase, reducing GTP. | ||||||
Flavopiridol | 146426-40-6 | sc-202157 sc-202157A | 5 mg 25 mg | $78.00 $259.00 | 41 | |
CDK inhibitor that disrupts cell cycle and transcription. | ||||||
DRB | 53-85-0 | sc-200581 sc-200581A sc-200581B sc-200581C | 10 mg 50 mg 100 mg 250 mg | $43.00 $189.00 $316.00 $663.00 | 6 | |
Inhibits RNA polymerase II elongation. | ||||||
Thiolutin | 87-11-6 | sc-200387 sc-200387A | 1 mg 5 mg | $101.00 $406.00 | 1 | |
RNA polymerase inhibitor, disrupting transcription. | ||||||
C646 | 328968-36-1 | sc-364452 sc-364452A | 10 mg 50 mg | $265.00 $944.00 | 5 | |
Selective inhibitor of histone acetyltransferase p300. | ||||||
CX-5461 | 1138549-36-6 | sc-507275 | 5 mg | $245.00 | ||
Disrupts RNA polymerase I transcription of ribosomal RNA. | ||||||