Glut3 Inhibitors
Common Glut3 Inhibitors include, but are not limited to STF 31 CAS 724741-75-7, Quercetin CAS 117-39-5, S-(4-Nitrobenzyl)-6-thioinosine (NBTI, NBMPR) CAS 38048-32-7, Ethacrynic acid CAS 58-54-8 and O-(Carboxymethyl)hydroxylamine hemihydrochloride CAS 2921-14-4.
Glut3 inhibitors are compounds that belong to a chemical class designed to target Glucose Transporter 3 (Glut3). Glut3 is a member of the glucose transporter family responsible for facilitating the transport of glucose across cell membranes. It is particularly expressed in various tissues, including neurons, where it plays a crucial role in supplying glucose to energy-demanding cells. By modulating the activity of Glut3, these inhibitors aim to influence the uptake of glucose into cells, which in turn can impact cellular energy metabolism and homeostasis.
The study of Glut3 inhibitors is instrumental in investigating the intricacies of glucose transport mechanisms and their effects on cellular function. These inhibitors offer researchers a means to explore how altering Glut3 activity may influence glucose utilization by cells, especially those with high energy requirements such as neurons. Understanding the role of Glut3 and its inhibition can provide insights into metabolic pathways, cellular responses to glucose availability, and implications for various physiological processes. Through the manipulation of Glut3 activity, these inhibitors contribute to advancing our understanding of glucose transport and utilization in different cell types and tissues.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
STF 31 | 724741-75-7 | sc-364692 | 10 mg | $187.00 | 3 | |
A small molecule inhibitor that selectively targets GLUT3 by disrupting its function, potentially inhibiting glucose transport in cancer cells. | ||||||
Wiskostatin | 253449-04-6 | sc-204399 sc-204399A sc-204399B sc-204399C | 1 mg 5 mg 25 mg 50 mg | $49.00 $124.00 $441.00 $828.00 | 4 | |
Inhibits GLUT1 and GLUT3 glucose transporters, affecting glucose uptake in cancer cells and reducing proliferation. | ||||||
KRIBB11 | 342639-96-7 | sc-507391 | 5 mg | $95.00 | ||
A compound that downregulates GLUT3 expression, potentially impacting glucose uptake and metabolism in cancer cells. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
A flavonoid with potential inhibitory effects on GLUT3-mediated glucose transport, impacting cellular energy metabolism. | ||||||
S-(4-Nitrobenzyl)-6-thioinosine (NBTI, NBMPR) | 38048-32-7 | sc-200117 | 50 mg | $163.00 | 1 | |
An inhibitor that targets GLUT3, affecting glucose transport and potentially interfering with cellular glucose metabolism. | ||||||
Ethacrynic acid | 58-54-8 | sc-257424 sc-257424A | 1 g 5 g | $90.00 $300.00 | 5 | |
A compound that may inhibit GLUT3-mediated glucose transport, potentially affecting glucose uptake and cellular metabolism. | ||||||
O-(Carboxymethyl)hydroxylamine hemihydrochloride | 2921-14-4 | sc-207410B sc-207410 sc-207410A | 250 mg 1 g 10 g | $55.00 $107.00 $320.00 | ||
Inhibits GLUT3 function by targeting glycolytic enzymes, leading to decreased glucose uptake and disruption of cellular metabolism. | ||||||
Bisphenol A | 80-05-7 | sc-391751 sc-391751A | 100 mg 10 g | $300.00 $490.00 | 5 | |
A derivative of bisphenol A that has been suggested to inhibit GLUT3-mediated glucose transport, affecting cellular metabolism. | ||||||
Silymarin group, mixture of isomers | 65666-07-1 | sc-301806 | 50 g | $325.00 | ||
A natural compound with potential inhibitory effects on GLUT3, potentially impacting glucose uptake and metabolism. | ||||||