Molecular structure of S-(4-Nitrobenzyl)-6-thioinosine (NBTI, NBMPR), CAS Number: 38048-32-7
S-(4-Nitrobenzyl)-6-thioinosine (NBTI, NBMPR) (CAS 38048-32-7)
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Application:
S-(4-Nitrobenzyl)-6-thioinosine (NBTI, NBMPR) is an inhibitor of ENTs with potential anticancer, cardio-, and neuro- protective properties
CAS Number:
38048-32-7
Purity:
≥98%
Molecular Weight:
419.4
Molecular Formula:
C17H17N5O6S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
S-(4-Nitrobenzyl)-6-thioinosine (NBTI, NBMPR) is a small molecule inhibitor of equilibrative nucleoside transporter (ENT) proteins. These transport proteins are described in relation to their sensitivity to S-(4-Nitrobenzyl)-6-thioinosine (NBTI, NBMPR), designated as either es (S-(4-Nitrobenzyl)-6-thioinosine (NBTI, NBMPR)-sensitive) or ei (S-(4-Nitrobenzyl)-6-thioinosine (NBTI, NBMPR)-insensitive). They provide good research tools anticancer, antiviral, cardioprotective, and neuroprotective agents. Inhibition of ENT1 by S-(4-Nitrobenzyl)-6-thioinosine (NBTI, NBMPR) blocks the uptake and transport of adenosine, which affects the regulation of extracellular adenosine levels and the cardiac system signaling associated with adenosine.
S-(4-Nitrobenzyl)-6-thioinosine (NBTI, NBMPR) (CAS 38048-32-7) References
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Inhibitor of:
5′-nucleotidase, Adenosine deaminase, CNT1, ENT1, Glut3, SLC29 (solute carrier family 29), and SNX12.Activator of:
ENT2.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
S-(4-Nitrobenzyl)-6-thioinosine (NBTI, NBMPR), 50 mg | sc-200117 | 50 mg | $163.00 |