Date published: 2025-12-5

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GLI Antibodies

Santa Cruz Biotechnology supplies a comprehensive collection of GLI Antibodies for investigating the Hedgehog signaling pathway and its implications in various biological processes. Monoclonal GLI Antibodies are suitable for a variety of techniques, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). GLI proteins play a crucial role in mediating the effects of Hedgehog signaling, which is essential for cell differentiation, proliferation, and tissue patterning during embryonic development. Dysregulation of GLI proteins has been implicated in several cancers and developmental disorders, making them significant targets for therapeutic intervention and research. Understanding the function and regulation of GLI proteins is vital for advancing our knowledge of developmental biology and disease mechanisms. GLI Antibodies enable researchers to conduct detailed analyses of protein expression, localization, and interactions within cellular pathways. Investigating GLI protein activity helps reveal new insights into developmental processes and potential therapeutic strategies. Santa Cruz Biotechnology monoclonal GLI Antibodies support researchers worldwide in their pursuit of scientific discoveries and medical breakthroughs.

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GLI Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

GLI-1/GLI1 Antibody (A-7)

sc-515781mouse IgG1 κ1050-1068 (h)WB, IP, IF, IHC(P), ELISAm, r, h
9
(1)

GLI-1/GLI1 Antibody (C-1)

sc-515751mouse IgG1 κ781-1080 (h)WB, IP, IF, ELISAm, r, h
38
(12)

GLI-2 Antibody (C-10)

sc-271786mouse IgG1 κ841-1140 (h)WB, IP, IF, IHC(P), ELISAm, r, h
56
(14)

GLI-3 Antibody (B-4)

sc-74478mouse IgG2b κ1-280 (h)WB, IP, IF, IHC(P), ELISAm, r, h
5
(6)

GLI CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

GLI-2 CRISPR/Cas9 KO Plasmid (h)

sc-400839hGene KnockoutGFP0
(0)

GLI-2 HDR Plasmid (h)

sc-400839-HDRhHomology Directed RepairPuromycin0
(0)

GLI-2 Double Nickase Plasmid (h)

sc-400839-NIChGene KnockoutPuromycin0
(0)

GLI-2 Double Nickase Plasmid (h2)

sc-400839-NIC-2hGene KnockoutPuromycin0
(0)

GLI-2 CRISPR/Cas9 KO Plasmid (m)

sc-420576mGene KnockoutGFP0
(0)

GLI-2 HDR Plasmid (m)

sc-420576-HDRmHomology Directed RepairPuromycin0
(0)

GLI-2 Double Nickase Plasmid (m)

sc-420576-NICmGene KnockoutPuromycin0
(0)

GLI-2 Double Nickase Plasmid (m2)

sc-420576-NIC-2mGene KnockoutPuromycin0
(0)

GLI-3 CRISPR/Cas9 KO Plasmid (h)

sc-400853hGene KnockoutGFP0
(0)

GLI-3 HDR Plasmid (h)

sc-400853-HDRhHomology Directed RepairPuromycin0
(0)

GLI-3 Double Nickase Plasmid (h)

sc-400853-NIChGene KnockoutPuromycin0
(0)

GLI-3 Double Nickase Plasmid (h2)

sc-400853-NIC-2hGene KnockoutPuromycin0
(0)

GLI-3 CRISPR/Cas9 KO Plasmid (m)

sc-420577mGene KnockoutGFP0
(0)

GLI-3 HDR Plasmid (m)

sc-420577-HDRmHomology Directed RepairPuromycin0
(0)

GLI-3 Double Nickase Plasmid (m)

sc-420577-NICmGene KnockoutPuromycin0
(0)

GLI-3 Double Nickase Plasmid (m2)

sc-420577-NIC-2mGene KnockoutPuromycin0
(0)

GLI-4 CRISPR/Cas9 KO Plasmid (h)

sc-410793hGene KnockoutGFP0
(0)

GLI-4 HDR Plasmid (h)

sc-410793-HDRhHomology Directed RepairPuromycin0
(0)

GLI-4 Double Nickase Plasmid (h)

sc-410793-NIChGene KnockoutPuromycin0
(0)

GLI-4 Double Nickase Plasmid (h2)

sc-410793-NIC-2hGene KnockoutPuromycin0
(0)

GLI-1/GLI1 CRISPR/Cas9 KO Plasmid (h2)

sc-400266-KO-2hGene KnockoutGFP0
(0)

GLI-1/GLI1 HDR Plasmid (h2)

sc-400266-HDR-2hHomology Directed RepairPuromycin0
(0)

GLI-1/GLI1 Double Nickase Plasmid (h)

sc-400266-NIChGene KnockoutPuromycin0
(0)

GLI-1/GLI1 Double Nickase Plasmid (h2)

sc-400266-NIC-2hGene KnockoutPuromycin0
(0)

GLI-1/GLI1 CRISPR/Cas9 KO Plasmid (m)

sc-420575mGene KnockoutGFP0
(0)

GLI-1/GLI1 HDR Plasmid (m)

sc-420575-HDRmHomology Directed RepairPuromycin0
(0)

GLI-1/GLI1 Double Nickase Plasmid (m)

sc-420575-NICmGene KnockoutPuromycin0
(0)

GLI-1/GLI1 Double Nickase Plasmid (m2)

sc-420575-NIC-2mGene KnockoutPuromycin0
(0)

GLI CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

GLI-2 CRISPR Activation Plasmid (h)

sc-400839-ACThGene ActivationPuro, Blast, Hygro0
(0)

GLI-2 CRISPR Activation Plasmid (h2)

sc-400839-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

GLI-2 Lentiviral Activation Particles (h)

sc-400839-LAChGene ActivationPuro, Blast, Hygro0
(0)

GLI-2 Lentiviral Activation Particles (h2)

sc-400839-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

GLI-2 CRISPR Activation Plasmid (m)

sc-420576-ACTmGene ActivationPuro, Blast, Hygro0
(0)

GLI-2 CRISPR Activation Plasmid (m2)

sc-420576-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

GLI-2 Lentiviral Activation Particles (m)

sc-420576-LACmGene ActivationPuro, Blast, Hygro0
(0)

GLI-2 Lentiviral Activation Particles (m2)

sc-420576-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

GLI-3 CRISPR Activation Plasmid (h)

sc-400853-ACThGene ActivationPuro, Blast, Hygro0
(0)

GLI-3 CRISPR Activation Plasmid (h2)

sc-400853-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

GLI-3 Lentiviral Activation Particles (h)

sc-400853-LAChGene ActivationPuro, Blast, Hygro0
(0)

GLI-3 Lentiviral Activation Particles (h2)

sc-400853-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

GLI-3 CRISPR Activation Plasmid (m)

sc-420577-ACTmGene ActivationPuro, Blast, Hygro0
(0)

GLI-3 CRISPR Activation Plasmid (m2)

sc-420577-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

GLI-3 Lentiviral Activation Particles (m)

sc-420577-LACmGene ActivationPuro, Blast, Hygro0
(0)

GLI-3 Lentiviral Activation Particles (m2)

sc-420577-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

GLI-4 CRISPR Activation Plasmid (h)

sc-410793-ACThGene ActivationPuro, Blast, Hygro0
(0)

GLI-4 CRISPR Activation Plasmid (h2)

sc-410793-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

GLI-4 Lentiviral Activation Particles (h)

sc-410793-LAChGene ActivationPuro, Blast, Hygro0
(0)

GLI-4 Lentiviral Activation Particles (h2)

sc-410793-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

GLI-1/GLI1 CRISPR Activation Plasmid (h)

sc-400266-ACThGene ActivationPuro, Blast, Hygro0
(0)

GLI-1/GLI1 CRISPR Activation Plasmid (h2)

sc-400266-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

GLI-1/GLI1 Lentiviral Activation Particles (h)

sc-400266-LAChGene ActivationPuro, Blast, Hygro0
(0)

GLI-1/GLI1 Lentiviral Activation Particles (h2)

sc-400266-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

GLI-1/GLI1 CRISPR Activation Plasmid (m)

sc-420575-ACTmGene ActivationPuro, Blast, Hygro0
(0)

GLI-1/GLI1 CRISPR Activation Plasmid (m2)

sc-420575-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

GLI-1/GLI1 Lentiviral Activation Particles (m)

sc-420575-LACmGene ActivationPuro, Blast, Hygro0
(0)

GLI-1/GLI1 Lentiviral Activation Particles (m2)

sc-420575-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

GLI siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

GLI-2 siRNA (h)

sc-37913hGene SilencingN/A
9
(0)

GLI-2 shRNA Plasmid (h)

sc-37913-SHhGene SilencingPuromycin
9
(0)

GLI-2 shRNA (h) Lentiviral Particles

sc-37913-VhGene SilencingPuromycin
9
(0)

GLI-2 siRNA (m)

sc-145421mGene SilencingN/A0
(0)

GLI-2 shRNA Plasmid (m)

sc-145421-SHmGene SilencingPuromycin0
(0)

GLI-2 shRNA (m) Lentiviral Particles

sc-145421-VmGene SilencingPuromycin0
(0)

GLI-3 siRNA (h)

sc-35483hGene SilencingN/A
1
(0)

GLI-3 shRNA Plasmid (h)

sc-35483-SHhGene SilencingPuromycin
1
(0)

GLI-3 shRNA (h) Lentiviral Particles

sc-35483-VhGene SilencingPuromycin
1
(0)

GLI-3 siRNA (m)

sc-35484mGene SilencingN/A0
(0)

GLI-3 shRNA Plasmid (m)

sc-35484-SHmGene SilencingPuromycin0
(0)

GLI-3 shRNA (m) Lentiviral Particles

sc-35484-VmGene SilencingPuromycin0
(0)

GLI-4 siRNA (h)

sc-75140hGene SilencingN/A0
(0)

GLI-4 shRNA Plasmid (h)

sc-75140-SHhGene SilencingPuromycin0
(0)

GLI-4 shRNA (h) Lentiviral Particles

sc-75140-VhGene SilencingPuromycin0
(0)

GLI-1/GLI1 siRNA (h)

sc-37911hGene SilencingN/A
28
(0)

GLI-1/GLI1 shRNA Plasmid (h)

sc-37911-SHhGene SilencingPuromycin
28
(0)

GLI-1/GLI1 shRNA (h) Lentiviral Particles

sc-37911-VhGene SilencingPuromycin
28
(0)

GLI-1/GLI1 siRNA (m)

sc-37912mGene SilencingN/A
2
(0)

GLI-1/GLI1 shRNA Plasmid (m)

sc-37912-SHmGene SilencingPuromycin
2
(0)

GLI-1/GLI1 shRNA (m) Lentiviral Particles

sc-37912-VmGene SilencingPuromycin
2
(0)

GLI-1/GLI1 siRNA (r)

sc-270268rGene SilencingN/A
1
(0)

GLI-1/GLI1 shRNA Plasmid (r)

sc-270268-SHrGene SilencingPuromycin
1
(0)

GLI-1/GLI1 shRNA (r) Lentiviral Particles

sc-270268-VrGene SilencingPuromycin
1
(0)