Date published: 2026-4-30

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Gl Syn Inhibitors

Glucose Synthase (Gl Syn) inhibitors are a specialized class of chemical compounds that interfere with the enzymatic process responsible for the synthesis of glucose within organisms. These inhibitors specifically target and impede the activity of glucose synthase, an enzyme pivotal in the conversion of glucose-6-phosphate into starch and other glucose polymers. By blocking this enzymatic function, Gl Syn inhibitors play a critical role in regulating and reducing the synthesis of glucose, which can have far-reaching implications in various metabolic pathways. The inhibition of glucose synthase alters the balance of glucose and its polymers within cells, leading to shifts in the energy storage and utilization processes. These compounds are often studied for their potential to modulate glucose levels in different organisms, offering insights into the metabolic control mechanisms at the cellular level. From a chemical standpoint, Gl Syn inhibitors can vary widely in structure, encompassing a range of molecular frameworks that share the common feature of being able to bind to the active site of glucose synthase or interfere with its substrate binding. This binding often involves a high degree of specificity, with inhibitors mimicking the natural substrates or acting as allosteric modulators that induce conformational changes in the enzyme, rendering it inactive. The structural diversity of these inhibitors allows for extensive research into their binding affinities, mechanisms of action, and potential for fine-tuning enzyme activity. Studies often focus on the kinetics of enzyme inhibition, exploring how these compounds can be optimized for greater efficacy in glucose synthesis suppression. Understanding the precise interaction between Gl Syn inhibitors and glucose synthase is crucial for advancing knowledge in enzymology and metabolic regulation.

Items 1 to 10 of 11 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

L-α-Aminoadipic acid

1118-90-7sc-202200
sc-202200A
50 mg
250 mg
$19.00
$32.00
(0)

L-α-Aminoadipic acid is a key intermediate in the lysine biosynthetic pathway, exhibiting unique interactions with enzymes involved in amino acid metabolism. Its carboxylic acid groups facilitate hydrogen bonding, influencing reaction kinetics and stability in biochemical processes. The compound's stereochemistry contributes to its role in metabolic pathways, allowing for specific enzyme-substrate interactions that drive the synthesis of essential biomolecules. Its solubility characteristics further enhance its reactivity in various biochemical environments.

L-Methionine [R,S]-Sulfoximine

15985-39-4sc-207806
1 g
$396.00
(0)

L-Methionine [R,S]-Sulfoximine is a notable compound in sulfur chemistry, characterized by its sulfoximine functional group, which enhances its reactivity through unique electron-donating properties. This compound exhibits distinct molecular interactions, particularly with nucleophiles, facilitating diverse reaction pathways. Its stereochemical configuration influences the kinetics of reactions, allowing for selective transformations. Additionally, its solubility in polar solvents promotes its participation in various chemical environments, enhancing its versatility in synthetic applications.

DL-2-Aminoadipic acid

542-32-5sc-255121
sc-255121A
1 g
5 g
$70.00
$227.00
(0)

DL-2-Aminoadipic acid is a unique compound in amino acid chemistry, distinguished by its dual amine and carboxylic acid functionalities. This structure allows for intricate hydrogen bonding and electrostatic interactions, influencing its reactivity in peptide synthesis. The compound participates in various metabolic pathways, showcasing its role in transamination reactions. Its ability to form stable complexes with metal ions further enhances its reactivity, making it a key player in biochemical processes.

Glufosinate-ammonium

77182-82-2sc-235254
sc-235254A
sc-235254B
sc-235254D
100 mg
25 g
100 g
1 kg
$43.00
$63.00
$135.00
$1259.00
8
(1)

Phosphinothricin acts as a glutamine synthetase inhibitor by mimicking glutamate, the substrate for the enzyme.

Bialaphos Sodium Salt

71048-99-2sc-280620
sc-280620A
100 mg
500 mg
$450.00
$992.00
1
(1)

Bialaphos is a natural product that gets converted into phosphinothricin in plants, subsequently inhibiting glutamine synthetase.

Azaserine

115-02-6sc-29063
sc-29063A
50 mg
250 mg
$312.00
$924.00
15
(3)

Azaserine is an analog of glutamine and acts as an inhibitor of glutamine-utilizing enzymes, including glutamine synthetase.

Acivicin

42228-92-2sc-200498B
sc-200498C
sc-200498
sc-200498D
1 mg
5 mg
10 mg
25 mg
$104.00
$416.00
$655.00
$1301.00
10
(2)

Acivicin is a glutamine analog that can inhibit enzymes involved in glutamine metabolism, including glutamine synthetase.

Clioquinol

130-26-7sc-201066
sc-201066A
1 g
5 g
$45.00
$115.00
2
(1)

Clioquinol can chelate copper, a cofactor necessary for the activity of glutamine synthetase, potentially reducing its activity.

6-Diazo-5-oxo-L-norleucine

157-03-9sc-227078
sc-227078A
sc-227078B
sc-227078C
5 mg
25 mg
100 mg
250 mg
$88.00
$291.00
$926.00
$2195.00
(0)

DON is a glutamine analog that inhibits various glutamine-utilizing enzymes, including glutamine synthetase.

L-Lysine

56-87-1sc-207804
sc-207804A
sc-207804B
25 g
100 g
1 kg
$95.00
$263.00
$529.00
(1)

Elevated levels of lysine have been shown to downregulate the expression of enzymes involved in ammonia assimilation, including glutamine synthetase.