These chemical activators play critical roles in modulating the activity of the GIN1 protein. EGCG inhibits the negative regulator of GIN1, allowing for increased GIN1 activity. Resveratrol promotes the translocation of GIN1 to the nucleus, where it can exert its function. Curcumin enhances GIN1 phosphorylation, resulting in increased GIN1 activity. Forskolin increases cAMP levels, which subsequently activates GIN1 signaling. Retinoic acid promotes GIN1 binding to specific DNA sequences, leading to the activation of target genes. SB203580 inhibits the negative regulator of GIN1, leading to increased GIN1 activity.
Thrombin induces conformational changes in the GIN1 protein structure, stimulating its activity. H2O2 promotes the oxidation of GIN1, leading to its activation. 8-Bromo-cAMP increases cAMP levels, triggering GIN1 activation. Genistein enhances GIN1 phosphorylation, resulting in increased GIN1 activity. AICAR activates GIN1 through its role in cellular energy metabolism and AMPK activation. GW5074 promotes the binding of GIN1 to specific interacting partners, facilitating its activation. These chemical activators provide diverse mechanisms for activating the GIN1 protein, highlighting their roles in regulating GIN1 activity in various cellular contexts.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
EGCG activates GIN1 by inhibiting its negative regulator, leading to increased GIN1 activity. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Resveratrol activates GIN1 by promoting its translocation to the nucleus, where it can exert its function. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin enhances GIN1 phosphorylation, resulting in increased GIN1 activity. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin activates GIN1 by increasing cAMP levels, which subsequently activates GIN1 signaling. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Retinoic acid promotes GIN1 binding to specific DNA sequences, leading to activation of target genes. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $90.00 $349.00 | 284 | |
SB203580 activates GIN1 by inhibiting its negative regulator, resulting in increased GIN1 activity. | ||||||
Thrombin from human plasma | 9002-04-4 | sc-471713 | 100 U | $235.00 | ||
Thrombin stimulates GIN1 activity by inducing conformational changes in the protein structure. | ||||||
Hydrogen Peroxide | 7722-84-1 | sc-203336 sc-203336A sc-203336B | 100 ml 500 ml 3.8 L | $31.00 $61.00 $95.00 | 28 | |
H2O2 activates GIN1 by promoting its oxidation and subsequent activation. | ||||||
8-Bromo-cAMP | 76939-46-3 | sc-201564 sc-201564A | 10 mg 50 mg | $126.00 $328.00 | 30 | |
8-Bromo-cAMP activates GIN1 by increasing cAMP levels, leading to GIN1 activation. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $45.00 $164.00 $200.00 $402.00 $575.00 $981.00 $2031.00 | 46 | |
Genistein enhances GIN1 phosphorylation, resulting in increased GIN1 activity. | ||||||