GILZ Activators
GILZ Activators is a term that refers to a set of chemical compounds capable of boosting the activity or expression of the Glucocorticoid-Induced Leucine Zipper (GILZ) protein. GILZ is a protein encoded by the TSC22D3 gene in humans. It is particularly noted for its upregulation by glucocorticoids and is involved in key biological processes, including immune response regulation, apoptosis, cell proliferation, and differentiation. The modulation of GILZ protein plays a significant role in these cellular functions and events, and thus, the compounds that can enhance its activity or expression - collectively known as GILZ activators - can have a profound impact on these processes.
The mode of action of GILZ activators can vary. Some activators might directly enhance the activity of GILZ, strengthening its ability to interact with other proteins and signaling pathways within the cell. Others may operate indirectly by promoting the expression of the GILZ protein. These compounds might function at the genetic level, influencing the transcription or translation of the TSC22D3 gene to increase the production of the GILZ protein. Still, others could act on signaling pathways that subsequently impact GILZ. Regardless of their specific mechanisms, all GILZ activators share the overarching characteristic of boosting the activity or expression of the GILZ protein. Consequently, they can significantly influence the many cellular and biological processes that GILZ is involved in. These compounds serve as important tools for scientists trying to understand the myriad roles of GILZ in the context of cellular biology and function.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $91.00 $139.00 $374.00 | 36 | |
As a glucocorticoid, Dexamethasone may potentially induce GILZ expression due to its role in regulating immune and inflammatory responses. | ||||||
Prednisolone | 50-24-8 | sc-205815 sc-205815A | 1 g 5 g | $84.00 $253.00 | 2 | |
Prednisolone, another glucocorticoid, might stimulate GILZ expression as part of its effects on modulating inflammation and immune responses. | ||||||
Hydrocortisone | 50-23-7 | sc-300810 | 5 g | $102.00 | 6 | |
Hydrocortisone, a cortisol hormone, could induce GILZ expression due to its influence on stress responses and immune regulation. | ||||||
Mifepristone | 84371-65-3 | sc-203134 | 100 mg | $61.00 | 17 | |
Mifepristone, a glucocorticoid receptor antagonist, might stimulate GILZ expression by modulating glucocorticoid receptor signaling. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $153.00 $292.00 $489.00 $1325.00 $8465.00 $933.00 | 22 | |
DL-Sulforaphane, an isothiocyanate, could potentially induce GILZ expression due to its role in activating antioxidant and detoxification pathways. | ||||||
Caffeic acid phenethyl ester | 104594-70-9 | sc-200800 sc-200800A sc-200800B | 20 mg 100 mg 1 g | $71.00 $296.00 $612.00 | 19 | |
Caffeic acid phenethyl ester (CAPE) might stimulate GILZ expression due to its role in modulating NF-kB signaling pathway. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
(-)-Epigallocatechin Gallate might stimulate GILZ expression due to its role in modulating cellular stress responses and antioxidative mechanisms. | ||||||