Prednisolone (CAS 50-24-8)
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Prednisolone is a synthetic corticosteroid widely used in biochemical and physiological research due to its effects on inflammation and immune response. In research applications, this compound is a standard choice for studying glucocorticoid receptor activation and the subsequent transcriptional regulation of genes involved in inflammatory pathways. It serves as a tool for understanding the molecular basis of glucocorticoid action and the cellular mechanisms that underlie inflammation. Additionally, prednisolone is employed in experimental models to investigate the stress response, due to its role in mimicking the effects of endogenous corticosteroids. By analyzing the impact of prednisolone on various cell types, researchers can elucidate the complex interplay between corticosteroids and immune function. Furthermore, its applications extend to studies on the modulation of cell proliferation, apoptosis, and metabolism, providing a comprehensive picture of corticosteroid action at the cellular and systemic levels.
Prednisolone (CAS 50-24-8) References
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- Prednisolone- and sirolimus-eluting stent: Anti-inflammatory approach for inhibiting in-stent restenosis. | Lee, SY., et al. 2016. J Biomater Appl. 31: 36-44. PMID: 26873634
- Prednisolone degradation by UV/chlorine process: Influence factors, transformation products and mechanism. | Yin, K., et al. 2018. Chemosphere. 212: 56-66. PMID: 30138856
- Very-High-Dose Prednisolone Before ACTH for Treatment of Infantile Spasms: Evaluation of a Standardized Protocol. | Eliyan, Y., et al. 2019. Pediatr Neurol. 99: 16-22. PMID: 31331669
- Effects of prednisolone on behavioral and inflammatory profile in animal model of PTZ-induced seizure. | de Lima Rosa, G., et al. 2021. Neurosci Lett. 743: 135560. PMID: 33359047
- Treatment with High-Dose Prednisolone in Vigabatrin-Refractory Infantile Spasms. | Al-Shehhi, W., et al. 2022. Can J Neurol Sci. 49: 532-539. PMID: 34212837
- Identifying the Lowest Effective Initial Dose of Prednisolone for the Treatment of Subacute Granulomatous Thyroiditis: A Systematic Review and Meta-Analysis. | Soltani, A., et al. 2022. Curr Rev Clin Exp Pharmacol. 17: 135-143. PMID: 34636318
- Orally Fast Disintegrating Cyclodextrin/Prednisolone Inclusion-Complex Nanofibrous Webs for Potential Steroid Medications. | Celebioglu, A., et al. 2021. Mol Pharm. 18: 4486-4500. PMID: 34780196
- Prednisolone and mesenchymal stem cell preloading protect liver cell migration and mitigate extracellular matrix modification in transplanted decellularized rat liver. | Yaghoubi, A., et al. 2022. Stem Cell Res Ther. 13: 36. PMID: 35090559
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- Analysis of Prednisolone-Induced Osteoporosis Using the Japanese Adverse Drug Event Report Database. | Wakabayashi, W., et al. 2022. J Pharm Pharm Sci. 25: 369-376. PMID: 36608641
- Prednisolone prescribing practices for dogs in Australia. | Purcell, B., et al. 2023. PLoS One. 18: e0282440. PMID: 36854035
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Prednisolone, 1 g | sc-205815 | 1 g | $84.00 | |||
Prednisolone, 5 g | sc-205815A | 5 g | $253.00 |