GC-1 Activators
GC-1 Activators include a diverse array of compounds that indirectly stimulate the activity of GC-1, a protein linked to various cellular functions such as signaling, growth, and differentiation. These activators exert their effects through modulation of gene expression, influencing the upregulation of Olfactomedin-4, which in turn may lead to increased activity of GC-1. Key players in this modulation include forskolin, IBMX, and Dibutyryl-cAMP, which enhance intracellular cAMP levels. Elevated cAMP can stimulate a range of genes, including Olfactomedin-4, thereby potentially enhancing GC-1 activity. This upregulation is vital in cellular processes such as synaptic plasticity and neuronal development.
Other significant activators like Epidermal Growth Factor (EGF), Phorbol 12-myristate 13-acetate (PMA), and Retinoic Acid, all trans work through different pathways but with a similar outcome of influencing gene expression. EGF activates signaling pathways that may upregulate Olfactomedin-4, while PMA, as a PKC activator, and Retinoic Acid, all trans, a Vitamin A derivative, also modulate gene expression, potentially affecting Olfactomedin-4 levels. The impact of these modulations on GC-1 activity is crucial in processes such as cell differentiation and tissue development. Additionally, neurotrophins like Brain-Derived Neurotrophic Factor (BDNF) and Nerve Growth Factor (NGF) play a role in neural growth and repair by potentially upregulating Olfactomedin-4, subsequently influencing GC-1 activity. Furthermore, compounds like Taurine, Zinc Sulfate solution, and Hydrocortisone, through their respective influences on cellular signaling and gene expression, contribute to the regulation of GC-1 activity. These activators, through their varied mechanisms, underscore the complex regulation of GC-1 and highlight its importance in a range of cellular functions, from neurotransmission and osmoregulation to immune response and stress management.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin, an adenylate cyclase activator, indirectly enhances GC-1 activity. By increasing intracellular cAMP levels, it can upregulate the expression of various genes, including Olfactomedin-4. This upregulation may lead to a secondary increase in GC-1 expression, impacting processes like cellular signaling. | ||||||
IBMX | 28822-58-4 | sc-201188 sc-201188B sc-201188A | 200 mg 500 mg 1 g | $260.00 $350.00 $500.00 | 34 | |
IBMX, a non-selective inhibitor of phosphodiesterases, indirectly enhances GC-1 activity. By preventing cAMP degradation, IBMX can increase cAMP levels, potentially upregulating Olfactomedin-4 expression. This may indirectly lead to increased GC-1 activity, involved in processes like neuronal development. | ||||||
Dibutyryl-cAMP | 16980-89-5 | sc-201567 sc-201567A sc-201567B sc-201567C | 20 mg 100 mg 500 mg 10 g | $47.00 $136.00 $492.00 $4552.00 | 74 | |
Dibutyryl-cAMP, a cAMP analog, indirectly enhances GC-1 activity. Elevated cAMP levels can stimulate the expression of genes including Olfactomedin-4. Increased Olfactomedin-4 levels may lead to enhanced GC-1 expression, affecting cellular processes such as synaptic plasticity and olfactory signaling. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
PMA, a PKC activator, indirectly enhances GC-1 activity. By activating PKC, PMA influences gene expression, potentially including Olfactomedin-4. This can lead to secondary enhancement of GC-1 activity, which is significant in cellular signaling and neuronal function. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Retinoic Acid, all trans, a Vitamin A derivative, indirectly enhances GC-1 activity. It modulates gene expression, potentially influencing Olfactomedin-4. Enhanced Olfactomedin-4 expression may lead to increased GC-1 activity, affecting processes such as cell differentiation and tissue development. | ||||||
Adenosine 3′,5′-cyclic monophosphate | 60-92-4 | sc-217584 sc-217584A sc-217584B sc-217584C sc-217584D sc-217584E | 100 mg 250 mg 5 g 10 g 25 g 50 g | $116.00 $179.00 $265.00 $369.00 $629.00 $1150.00 | ||
Adenosine 3',5'-cyclic monophosphate, a secondary messenger, indirectly enhances GC-1 activity. Elevated levels of cAMP can stimulate gene expression, potentially affecting Olfactomedin-4. This may lead to increased GC-1 activity, impacting cellular signaling and metabolic processes. | ||||||
Taurine | 107-35-7 | sc-202354 sc-202354A | 25 g 500 g | $48.00 $102.00 | 1 | |
Taurine, an amino acid, indirectly enhances GC-1 activity. It can influence gene expression and cellular signaling pathways, potentially affecting Olfactomedin-4. Increased Olfactomedin-4 may lead to enhanced GC-1 activity, involved in processes like osmoregulation and neurotransmission. | ||||||
Zinc | 7440-66-6 | sc-213177 | 100 g | $48.00 | ||
Zinc Sulfate Solution indirectly enhances GC-1 activity. Zinc can modulate gene expression, possibly influencing Olfactomedin-4 levels. This modulation may lead to increased GC-1 activity, impacting cellular processes including immune response and enzyme regulation. | ||||||
Hydrocortisone | 50-23-7 | sc-300810 | 5 g | $102.00 | 6 | |
Hydrocortisone, a corticosteroid, indirectly enhances GC-1 activity. It can affect gene expression, potentially upregulating Olfactomedin-4. Increased Olfactomedin-4 levels may lead to enhanced GC-1 activity, influencing processes like inflammation regulation and stress response. | ||||||