Date published: 2026-4-25

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GBX2 Activators

The compounds capable of potentially influencing Gastrulation Brain Homeobox 2 (GBX2) activity represent a wide-ranging classification. This group includes agents such as Retinoic Acid and All-trans Retinoic Acid. These compounds, metabolites of vitamin A, can influence cellular differentiation, which in turn can play a role in GBX2 activity. Another influential compound is Forskolin, an activator of adenylate cyclase. This compound can elevate cAMP levels, making an impact on GBX2 through cAMP-dependent pathways. Phorbol 12-Myristate 13-Acetate (PMA), a potent activator of Protein Kinase C (PKC), is also significant, as it can indirectly modify GBX2 activity by regulating PKC-dependent pathways.

There are also growth factors like Epidermal Growth Factor (EGF) and Fibroblast Growth Factor 2 (FGF2), as well as hormones like Insulin and Insulin-like Growth Factor 1 (IGF-1). These compounds can stimulate cell growth and differentiation, an activity that can potentially make an impression on GBX2. Further, there are cytokines like Leukemia Inhibitory Factor (LIF), which can influence various cellular processes, and Bone Morphogenetic Protein 4 (BMP4), which is actively engaged in embryonic development and differentiation. These compounds can potentially have an effect on GBX2 activity.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Retinoic Acid, all trans

302-79-4sc-200898
sc-200898A
sc-200898B
sc-200898C
500 mg
5 g
10 g
100 g
$66.00
$325.00
$587.00
$1018.00
28
(1)

Retinoic Acid is a metabolic product of vitamin A that is involved in cellular differentiation and may affect GBX2 activity.

Dexamethasone

50-02-2sc-29059
sc-29059B
sc-29059A
100 mg
1 g
5 g
$91.00
$139.00
$374.00
36
(1)

Dexamethasone is a glucocorticoid that can influence numerous cellular processes and potentially impact GBX2.

Forskolin

66575-29-9sc-3562
sc-3562A
sc-3562B
sc-3562C
sc-3562D
5 mg
50 mg
1 g
2 g
5 g
$78.00
$153.00
$740.00
$1413.00
$2091.00
73
(3)

Forskolin is an activator of adenylate cyclase and can raise cAMP levels, potentially affecting GBX2 activity through cAMP-dependent pathways.

Genistein

446-72-0sc-3515
sc-3515A
sc-3515B
sc-3515C
sc-3515D
sc-3515E
sc-3515F
100 mg
500 mg
1 g
5 g
10 g
25 g
100 g
$45.00
$164.00
$200.00
$402.00
$575.00
$981.00
$2031.00
46
(1)

Genistein is a phytoestrogen that can influence various cellular processes, potentially influencing GBX2.

PMA

16561-29-8sc-3576
sc-3576A
sc-3576B
sc-3576C
sc-3576D
1 mg
5 mg
10 mg
25 mg
100 mg
$41.00
$132.00
$214.00
$500.00
$948.00
119
(6)

PMA is a potent activator of Protein Kinase C (PKC), which may indirectly influence GBX2 activity by modulating PKC-dependent pathways.

Insulin

11061-68-0sc-29062
sc-29062A
sc-29062B
100 mg
1 g
10 g
$156.00
$1248.00
$12508.00
82
(1)

Insulin is a hormone that controls many metabolic processes and could possibly impact GBX2.

Mifepristone

84371-65-3sc-203134
100 mg
$61.00
17
(1)

Mifepristone, is a cytokine that can influence various cellular processes, potentially influencing GBX2.