Date published: 2026-7-2

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gasdermin Antibodies

Santa Cruz Biotechnology supplies a comprehensive collection of gasdermin monoclonal antibodies for research focused on understanding gasdermin proteins in biological processes. Gasdermin monoclonal antibodies are suitable for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Gasdermin proteins function as key mediators of pyroptosis, a form of programmed cell death associated with inflammation and immune responses. The pore-forming capability of gasdermin in cellular membranes significantly influences pro-inflammatory cytokine release, making gasdermin an important focus in inflammatory disease research and therapeutic development. Research into gasdermin function reveals essential information about cell death mechanisms and immune response regulation. Investigating gasdermin activity helps advance understanding of various inflammatory conditions and potential treatment approaches. Exploring gasdermin's role in cellular processes provides valuable insights into disease progression and therapeutic strategies. Current research continues to uncover new aspects of gasdermin biology and its impact on human health. Santa Cruz Biotechnology monoclonal antibodies for gasdermin research support scientists in advancing our understanding of inflammatory diseases and immune system function.

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gasdermin Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

gasdermin Antibody (H-6)

sc-376318mouse IgG1 κ1-196 (h)WB, IP, IF, ELISAm, r, h
9
(4)

GSDMDC1 Antibody (64-Y)

sc-81868mouse IgG1 κ1-485 (h)WB, IP, IF, IHC(P), ELISAh
53
(12)

GSDMDC1 Antibody (H-11)

sc-393581mouse IgG2b κ169-188 (m)WB, IP, IF, ELISAm, r, h
74
(8)

GSDMDC1 Antibody (A-7)

sc-393656mouse IgG1 κ169-188 (m)WB, IP, IF, ELISAm, r
59
(3)

gasdermin siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

gasdermin siRNA (h)

sc-75109hGene SilencingN/A0
(0)

gasdermin shRNA Plasmid (h)

sc-75109-SHhGene SilencingPuromycin0
(0)

gasdermin shRNA (h) Lentiviral Particles

sc-75109-VhGene SilencingPuromycin0
(0)

gasdermin siRNA (m)

sc-75110mGene SilencingN/A0
(0)

gasdermin shRNA Plasmid (m)

sc-75110-SHmGene SilencingPuromycin0
(0)

gasdermin shRNA (m) Lentiviral Particles

sc-75110-VmGene SilencingPuromycin0
(0)

gasdermin C siRNA (h)

sc-77600hGene SilencingN/A0
(0)

gasdermin C shRNA Plasmid (h)

sc-77600-SHhGene SilencingPuromycin0
(0)

gasdermin C shRNA (h) Lentiviral Particles

sc-77600-VhGene SilencingPuromycin0
(0)

gasdermin C siRNA (m)

sc-149473mGene SilencingN/A0
(0)

gasdermin C shRNA Plasmid (m)

sc-149473-SHmGene SilencingPuromycin0
(0)

gasdermin C shRNA (m) Lentiviral Particles

sc-149473-VmGene SilencingPuromycin0
(0)

GSDMDC1 siRNA (h)

sc-77581hGene SilencingN/A0
(0)

GSDMDC1 shRNA Plasmid (h)

sc-77581-SHhGene SilencingPuromycin0
(0)

GSDMDC1 shRNA (h) Lentiviral Particles

sc-77581-VhGene SilencingPuromycin0
(0)

GSDMDC1 siRNA (m)

sc-145798mGene SilencingN/A
2
(0)

GSDMDC1 shRNA Plasmid (m)

sc-145798-SHmGene SilencingPuromycin
2
(0)

GSDMDC1 shRNA (m) Lentiviral Particles

sc-145798-VmGene SilencingPuromycin
2
(0)

gasdermin A2 siRNA (m)

sc-145335mGene SilencingN/A0
(0)

gasdermin A2 shRNA Plasmid (m)

sc-145335-SHmGene SilencingPuromycin0
(0)

gasdermin A2 shRNA (m) Lentiviral Particles

sc-145335-VmGene SilencingPuromycin0
(0)

gasdermin A3 siRNA (m)

sc-145336mGene SilencingN/A0
(0)

gasdermin A3 shRNA Plasmid (m)

sc-145336-SHmGene SilencingPuromycin0
(0)

gasdermin A3 shRNA (m) Lentiviral Particles

sc-145336-VmGene SilencingPuromycin0
(0)

gasdermin CRISPR Knockout (KO) and HDR Plasmids

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

gasdermin CRISPR/Cas9 KO Plasmid (h)

sc-410658Gene Knockouth0
(0)

gasdermin HDR Plasmid (h)

sc-410658-HDRHomology Directed Repairh0
(0)

gasdermin C CRISPR/Cas9 KO Plasmid (h)

sc-412690Gene Knockouth0
(0)

gasdermin C HDR Plasmid (h)

sc-412690-HDRHomology Directed Repairh0
(0)

gasdermin C CRISPR/Cas9 KO Plasmid (m)

sc-429915Gene Knockoutm0
(0)

GSDMDC1 CRISPR/Cas9 KO Plasmid (h2)

sc-406596-KO-2Gene Knockouth0
(0)

GSDMDC1 CRISPR/Cas9 KO Plasmid (m)

sc-427312Gene Knockoutm0
(0)

GSDMDC1 HDR Plasmid (m)

sc-427312-HDRHomology Directed Repairm0
(0)

GSDMDC1 CRISPR/Cas9 KO Plasmid (r)

sc-437380Gene Knockoutr0
(0)

gasdermin CRISPR Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

gasdermin Double Nickase Plasmid (h)

sc-410658-NICGene Knockouth0
(0)

gasdermin Double Nickase Plasmid (h2)

sc-410658-NIC-2Gene Knockouth0
(0)

gasdermin C Double Nickase Plasmid (h)

sc-412690-NICGene Knockouth0
(0)

gasdermin C Double Nickase Plasmid (h2)

sc-412690-NIC-2Gene Knockouth0
(0)

GSDMDC1 Double Nickase Plasmid (h)

sc-406596-NICGene Knockouth0
(0)

GSDMDC1 Double Nickase Plasmid (h2)

sc-406596-NIC-2Gene Knockouth0
(0)

gasdermin CRISPR Activation Plasmids and Lentiviral Particles

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

gasdermin CRISPR Activation Plasmid (h)

sc-410658-ACTGene Activationh0
(0)

gasdermin CRISPR Activation Plasmid (h2)

sc-410658-ACT-2Gene Activationh0
(0)

GSDMDC1 CRISPR Activation Plasmid (h)

sc-406596-ACTGene Activationh0
(0)

GSDMDC1 CRISPR Activation Plasmid (h2)

sc-406596-ACT-2Gene Activationh0
(0)

GSDMDC1 CRISPR Activation Plasmid (m)

sc-427312-ACTGene Activationm0
(0)

GSDMDC1 CRISPR Activation Plasmid (m2)

sc-427312-ACT-2Gene Activationm0
(0)