Date published: 2026-4-30

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GSDMDC1 Antibody (H-11): sc-393581

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Datasheets
  • GSDMDC1 Antibody (H-11) is a mouse monoclonal IgG2b κ, cited in 74 publications, provided at 200 µg/ml
  • specific for an epitope mapping between amino acids 169-188 within an internal region of GSDMDC1 of mouse origin
  • Anti-GSDMDC1 Antibody (H-11) is recommended for detection of GSDMDC1 of mouse, rat and human origin by WB, IP, IF and ELISA
  • Anti-GSDMDC1 Antibody (H-11) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
  • also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
  • also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
  • also available conjugated to biotin for WB, IHC(P) and ELISA
  • m-IgG2b BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for GSDMDC1 Antibody (H-11) for WB applications. These reagents are now offered in bundles with GSDMDC1 Antibody (H-11) (see ordering information below).
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GSDMDC1 Antibody (H-11) is a mouse monoclonal IgG2b kappa light chain antibody that detects GSDMDC1 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). GSDMDC1 (H-11) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. GSDMDC1, consisting of 484 amino acids, plays a crucial role in regulating cell death and inflammation, particularly in pyroptosis, a form of programmed cell death associated with inflammatory responses. Understanding GSDMDC1 function is vital, as dysregulation has been implicated in various diseases, including cancer and inflammatory disorders. GSDMDC1 gene is located on human chromosome 8, a region significant for involvement in certain leukemias and lymphomas, as well as associations with various genetic disorders, such as schizophrenia and bipolar disorder. GSDMDC1 presence in these pathways highlights potential as a therapeutic target and biomarker for disease progression.

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA

LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

GSDMDC1 Antibody (H-11)

sc-393581
200 µg/ml
$322.00

GSDMDC1 Antibody (H-11): m-IgGκ BP-HRP Bundle

sc-524012
200 µg Ab, 40 µg BP
$361.00

GSDMDC1 Antibody (H-11): m-IgG2b BP-HRP Bundle

sc-549149
200 µg Ab; 10 µg BP
$361.00

GSDMDC1 Antibody (H-11) AC

sc-393581 AC
500 µg/ml, 25% agarose
$424.00

GSDMDC1 Antibody (H-11) HRP

sc-393581 HRP
200 µg/ml
$322.00

GSDMDC1 Antibody (H-11) FITC

sc-393581 FITC
200 µg/ml
$336.00

GSDMDC1 Antibody (H-11) PE

sc-393581 PE
200 µg/ml
$349.00

GSDMDC1 Antibody (H-11) Alexa Fluor® 488

sc-393581 AF488
200 µg/ml
$364.00

GSDMDC1 Antibody (H-11) Alexa Fluor® 546

sc-393581 AF546
200 µg/ml
$364.00

GSDMDC1 Antibody (H-11) Alexa Fluor® 594

sc-393581 AF594
200 µg/ml
$364.00

GSDMDC1 Antibody (H-11) Alexa Fluor® 647

sc-393581 AF647
200 µg/ml
$364.00

GSDMDC1 Antibody (H-11) Alexa Fluor® 680

sc-393581 AF680
200 µg/ml
$364.00

GSDMDC1 Antibody (H-11) Alexa Fluor® 790

sc-393581 AF790
200 µg/ml
$364.00

GSDMDC1 Antibody (H-11) B

sc-393581 B
200 µg/ml
$326.00

I want to know whether GSDMDC1 equals gasdermin D-C terminal part? Thank you

Asked by: weer
Thank you for your question. This GSDMDC1 antibody, sc-393581, is specific for an epitope mapping between amino acids 169-188 within an internal region of GSDMDC1 of mouse origin (accession#Q9D8T2).
Answered by: Tech Service
Date published: 2022-08-31

Can i use in rat`s GSDMD?

Asked by: yougar
Thank you for your question. This antibody is recommended for detection of GSDMDC1 of mouse, rat and human origin.
Answered by: Technical Support
Date published: 2022-07-25

Would be possible to see the Full lenght and N-terminal fragmentation in western blott analysis?

Asked by: lson
Thank you for your question. GSDMDC1 Antibody (H-11): sc-393581 is specific for an epitope mapping between amino acids 169-188 within an internal region of GSDMDC1 of mouse origin. The antibody will not detect the N-terminal murine protein fragment A0A2R8W727-1, if that is what you are referring to. This fragment only covers an amino acid range from aa 1-57 of the full-length protein, which does not correspond to the antibody's epitope region. Please get in touch with our technical service if you require further information.
Answered by: Tech Support Europe
Date published: 2022-05-12

I have some canine samples I want to test. Do you think sc-393581 will cross-react?

Asked by: Cweed
Please contact our Technical Service Department and we would be happy to perform sequence analysis and review our data to answer any questions you may have about additional species reactivity.
Answered by: Technical Support 4
Date published: 2017-01-17
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Rated 5 out of 5 by from 功能很出色!效价高!产品很好,用起来效果很好。值得购买!以后会经常购买此类产品,并推荐给身边的朋友购买!希望贵司多出新品!谢谢
Date published: 2022-08-25
Rated 4 out of 5 by from Good antibodyI tried the free samples and it worked for WB and IF in BMDMs.
Date published: 2018-05-03
Rated 4 out of 5 by from Moderate bands in H460This antibody worked 1:500 concentration for western; detected a moderate band in H460 cell line.
Date published: 2018-04-18
Rated 5 out of 5 by from 功能很出色我一年前买了该产品,用的很好。我使用的稀释比例为1:300,还可以,就是有一些杂带,不知道是有意义的呢?还是单纯的杂带。
Date published: 2018-04-17
Rated 5 out of 5 by from it' very good!This antibody is a month before I bought, very easy to use, the specificity is relatively high when used for the WB.
Date published: 2017-08-23
Rated 4 out of 5 by from Worked well for WBWe could detect a clear band for Gasdermin with WB. The antibody worked well and gave good signals.
Date published: 2017-08-15
Rated 5 out of 5 by from Good band for WBNice band at 53 kDa when using GSDMDC1 (H-11) for Western blot.
Date published: 2016-12-20
Rated 5 out of 5 by from Very good Western blot data of GSDMDC1 expressionVery good Western blot data of GSDMDC1 expression in rat spleen tissue extract and WEHI-3 whole cell lysate . -SCBT QC
Date published: 2013-01-20
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GSDMDC1 Antibody (H-11) is rated 4.6 out of 5 by 8.
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