Date published: 2026-3-10

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Gas2 Inhibitors

Gas2 inhibitors belong to a chemical class of compounds that exhibit specific properties and functionalities. These inhibitors are designed to target and modulate the activity of the protein Gas2. Gas2, short for Growth Arrest-specific 2, is a cytoskeletal-associated protein that plays a crucial role in cellular processes such as cell growth, division, and migration. Gas2 inhibitors are meticulously crafted molecules that are engineered to interact with Gas2 protein and interfere with its normal function. The structural composition of Gas2 inhibitors typically involves a diverse range of chemical moieties, enabling them to bind selectively and tightly to the target protein. These compounds possess unique structural features that allow them to penetrate cellular membranes and reach the intracellular compartments where Gas2 is predominantly localized. Gas2 inhibitors often exhibit favorable physicochemical properties, such as adequate solubility, stability, and bioavailability, which facilitate their interaction with the target protein.

Gas2 inhibitors work by inhibiting or modulating the activity of Gas2 protein through various mechanisms. These mechanisms might involve interference with protein-protein interactions, disrupting Gas2's binding to other cellular components, or altering its subcellular localization. By specifically targeting Gas2, these inhibitors can potentially influence critical cellular processes that are regulated by this protein, including cytoskeletal dynamics, cell motility, and proliferation. Researchers and scientists are actively studying Gas2 inhibitors to elucidate their precise mode of action and explore their potential applications. By understanding the molecular mechanisms and effects of these inhibitors, scientists aim to gain insights into the fundamental cellular processes that rely on Gas2. The development of Gas2 inhibitors represents a promising area of research in chemical biology and may have implications in diverse fields such as cell biology, biochemistry, and molecular pharmacology.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Arctigenin

7770-78-7sc-202957
25 mg
$83.00
14
(1)

Arctigenin is a natural compound found in plants such as Arctium lappa (burdock). It has been reported to inhibit Gas2 expression and induce cell cycle arrest in certain cancer cell lines.

Fluorouracil

51-21-8sc-29060
sc-29060A
1 g
5 g
$37.00
$152.00
11
(1)

5-FU is a commonly used chemotherapy drug that inhibits DNA synthesis. It has been reported to downregulate the expression of Gas2 in colorectal cancer cells, thereby exerting its anticancer effects.

Cinnamic Aldehyde

104-55-2sc-294033
sc-294033A
100 g
500 g
$104.00
$228.00
(0)

Cinnamaldehyde is a natural compound found in cinnamon bark. It has been shown to inhibit the growth of cancer cells and induce cell cycle arrest. One study suggested that cinnamaldehyde may exert its effects, at least in part, through modulation of Gas2 expression.

Salinomycin

53003-10-4sc-253530
sc-253530C
sc-253530A
sc-253530B
5 mg
10 mg
25 mg
100 mg
$162.00
$241.00
$406.00
$474.00
1
(1)

Salinomycin is an antibiotic compound that has gained attention for its anticancer properties, particularly its ability to target cancer stem cells. It has been reported to downregulate Gas2 expression in breast cancer cells, leading to inhibition of cell growth and induction of apoptosis.

Geldanamycin

30562-34-6sc-200617B
sc-200617C
sc-200617
sc-200617A
100 µg
500 µg
1 mg
5 mg
$39.00
$59.00
$104.00
$206.00
8
(1)

Geldanamycin is a natural compound found in Streptomyces bacteria. It is known as an Hsp90 inhibitor, but studies have also suggested that geldanamycin may inhibit Gas2 function. It has been shown to induce apoptosis in cancer cells by disrupting the interaction between Gas2 and actin filaments.

Docetaxel

114977-28-5sc-201436
sc-201436A
sc-201436B
5 mg
25 mg
250 mg
$87.00
$332.00
$1093.00
16
(1)

Docetaxel is a widely used chemotherapeutic agent belonging to the taxane class. It inhibits microtubule dynamics and disrupts cell division. Recent studies have indicated that docetaxel may downregulate Gas2 expression, contributing to its anticancer effects.

Curcumin

458-37-7sc-200509
sc-200509A
sc-200509B
sc-200509C
sc-200509D
sc-200509F
sc-200509E
1 g
5 g
25 g
100 g
250 g
1 kg
2.5 kg
$37.00
$69.00
$109.00
$218.00
$239.00
$879.00
$1968.00
47
(1)

Curcumin is a natural polyphenol found in turmeric. It has been investigated for its various health benefits, including anticancer properties. Curcumin has been reported to suppress Gas2 expression in pancreatic cancer cells, leading to growth inhibition and apoptosis.

Resveratrol

501-36-0sc-200808
sc-200808A
sc-200808B
100 mg
500 mg
5 g
$80.00
$220.00
$460.00
64
(2)

Resveratrol is a natural compound found in grapes and red wine. It has been investigated for its potential health benefits, including anticancer properties. Resveratrol has been reported to inhibit Gas2 expression in lung cancer cells, leading to cell cycle arrest and apoptosis.