GARNL4 Activators
Items 11 to 17 of 17 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Gö 6983 | 133053-19-7 | sc-203432 sc-203432A sc-203432B | 1 mg 5 mg 10 mg | $105.00 $299.00 $474.00 | 15 | |
Gö6983 is a broad-spectrum PKC inhibitor that could enhance GARNL4 by decreasing PKC-mediated phosphorylation events that might negatively regulate RAP1GAP2's function. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
Rapamycin inhibits mTOR, which is involved in the regulation of cell growth and proliferation. As mTOR pathways can intersect with pathways involving GARNL4, inhibition by rapamycin could lead to a decrease in GARNL4 activity indirectly. | ||||||
Rolipram | 61413-54-5 | sc-3563 sc-3563A | 5 mg 50 mg | $77.00 $216.00 | 18 | |
Rolipram inhibits phosphodiesterase-4 (PDE4), leading to increased cAMP levels in cells, which may indirectly enhance GARNL4 activity by promoting the GTPase activating function of GARNL4 on RAP1. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
PD98059 is a MEK inhibitor similar to U0126 and can inhibit GARNL4 by reducing the activity of the ERK/MAPK pathway, which could be upstream of GARNL4 signaling pathways. | ||||||
PP 2 | 172889-27-9 | sc-202769 sc-202769A | 1 mg 5 mg | $94.00 $227.00 | 30 | |
PP2 is an Src family kinase inhibitor and can inhibit GARNL4 by targeting the Src family kinases that may phosphorylate proteins that are upstream or regulators of GARNL4. | ||||||
LY-333,531 Hydrochloride | 169939-93-9 | sc-364215 sc-364215A | 1 mg 5 mg | $94.00 $287.00 | 6 | |
LY333531 is a selective inhibitor of protein kinase C beta (PKCβ). If GARNL4 is regulated by PKCβ, either directly or indirectly, its inhibition can lead to decreased GARNL4 activity. | ||||||
A23187 | 52665-69-7 | sc-3591 sc-3591B sc-3591A sc-3591C | 1 mg 5 mg 10 mg 25 mg | $55.00 $131.00 $203.00 $317.00 | 23 | |
A23187 is an ionophore that increases intracellular calcium levels, which can affect RAP1 activity. Enhanced calcium signaling may indirectly support GARNL4 function by modulating the complex formation or localization of RAP1GAP2, thereby enhancing its GTPase activating activity towards RAP1. | ||||||