γ Enolase Inhibitors
The chemical class known as γ Enolase inhibitors encompasses a diverse range of compounds that either directly or indirectly modulate the activity of γ Enolase. While no direct inhibitors are listed, the indirect inhibitors presented showcase various mechanisms through which γ Enolase can be influenced. Fluoride disrupts glycolysis by inhibiting enolase's metal cofactor, impacting energy production and cellular processes. EGCG, a PI3K inhibitor, modulates the PI3K/AKT pathway, influencing γ Enolase indirectly and suggesting a connection between PI3K signaling and γ Enolase activity. 2-Deoxy-D-Glucose interferes with glycolysis, affecting energy production and cellular processes dependent on enolase function. Neomycin disrupts glycolysis by affecting ion gradients, influencing γ Enolase indirectly. PD98059, a MEK inhibitor, modulates the MAPK/ERK pathway, affecting cellular processes associated with MAPK/ERK activation and γ Enolase function. Auranofin targets redox signaling, impacting cellular processes dependent on redox balance and γ Enolase activity.
ML-9, a calmodulin inhibitor, modulates calcium signaling, influencing γ Enolase indirectly and suggesting a link between calmodulin activation and γ Enolase function. R406, a Syk inhibitor, influences the JAK/STAT pathway, affecting cellular processes associated with JAK/STAT activation and γ Enolase activity. 6-Azauridine interferes with nucleotide metabolism, suggesting a link between RNA synthesis and γ Enolase function. Wortmannin, a PI3K inhibitor, modulates the PI3K/AKT pathway, influencing γ Enolase indirectly. Piceatannol, a Syk inhibitor, influences the JAK/STAT pathway, affecting cellular processes associated with JAK/STAT activation and γ Enolase activity. SB203580, a p38 MAPK inhibitor, disrupts downstream signaling, highlighting a regulatory mechanism for γ Enolase through the p38 MAPK pathway. The diversity of these inhibitors underscores the complexity of γ Enolase regulation, providing insights into strategies targeting this enzyme. Understanding the mechanisms through which these chemicals modulate γ Enolase activity can inform further research into the role of γ Enolase in cellular processes and disease states.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Sodium Fluoride | 7681-49-4 | sc-24988A sc-24988 sc-24988B | 5 g 100 g 500 g | $39.00 $45.00 $98.00 | 26 | |
Fluoride is an indirect inhibitor of γ Enolase through its impact on glycolysis. By inhibiting enolase's metal cofactor, fluoride disrupts the glycolytic pathway, influencing γ Enolase indirectly. This interference with glycolysis affects energy production and cellular processes dependent on enolase activity. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
EGCG indirectly inhibits γ Enolase through its modulation of the PI3K/AKT pathway. As an inhibitor of PI3K, EGCG impacts downstream signaling, influencing γ Enolase indirectly. This modulation can affect cellular processes associated with PI3K/AKT activation, highlighting a potential regulatory mechanism for γ Enolase. | ||||||
2-Deoxy-D-glucose | 154-17-6 | sc-202010 sc-202010A | 1 g 5 g | $65.00 $210.00 | 26 | |
2-Deoxy-D-Glucose indirectly inhibits γ Enolase by interfering with glycolysis. As a glucose analog, it disrupts glucose metabolism, impacting enolase activity and influencing γ Enolase indirectly. This modulation of glycolysis can affect energy production and cellular processes dependent on enolase function. | ||||||
Neomycin sulfate | 1405-10-3 | sc-3573 sc-3573A | 1 g 5 g | $26.00 $34.00 | 20 | |
Neomycin indirectly inhibits γ Enolase through its impact on glycolysis. By disrupting cell membrane integrity, neomycin affects ion gradients and glycolysis, influencing γ Enolase indirectly. This interference with glycolysis can impact energy production and cellular processes dependent on enolase activity. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
PD98059 indirectly inhibits γ Enolase by modulating the MAPK/ERK pathway. As a MEK inhibitor, PD98059 disrupts downstream signaling, influencing γ Enolase indirectly. This modulation can affect cellular processes associated with MAPK/ERK activation, highlighting a potential regulatory mechanism for γ Enolase. | ||||||
Auranofin | 34031-32-8 | sc-202476 sc-202476A sc-202476B | 25 mg 100 mg 2 g | $150.00 $210.00 $1899.00 | 39 | |
Auranofin indirectly inhibits γ Enolase through its impact on redox signaling. By targeting thioredoxin reductase, auranofin influences redox balance, impacting cellular processes dependent on redox signaling and γ Enolase function. This modulation suggests a potential link between redox regulation and γ Enolase activity. | ||||||
ML-9 | 105637-50-1 | sc-200519 sc-200519A sc-200519B sc-200519C | 10 mg 50 mg 100 mg 250 mg | $110.00 $440.00 $660.00 $1200.00 | 2 | |
ML-9 indirectly inhibits γ Enolase by modulating the calmodulin pathway. As a calmodulin inhibitor, ML-9 disrupts calcium signaling, influencing γ Enolase indirectly. This modulation can affect cellular processes associated with calmodulin activation, highlighting a potential regulatory mechanism for γ Enolase. | ||||||
R406 | 841290-81-1 | sc-364595 sc-364595A | 2 mg 10 mg | $160.00 $370.00 | 16 | |
R406 indirectly inhibits γ Enolase through its impact on the JAK/STAT pathway. As a Syk inhibitor, R406 influences downstream signaling, affecting cellular processes associated with JAK/STAT activation and γ Enolase function. This modulation suggests a potential link between immune signaling and γ Enolase activity. | ||||||
6-Azauridine | 54-25-1 | sc-221082B sc-221082 sc-221082C sc-221082A | 500 mg 1 g 2 g 5 g | $95.00 $156.00 $289.00 $666.00 | ||
6-Azauridine indirectly inhibits γ Enolase by interfering with nucleotide metabolism. As a pyrimidine analog, it disrupts RNA synthesis, impacting cellular processes dependent on nucleotide-derived molecules and γ Enolase function. This interference with nucleotide metabolism suggests a potential link between RNA synthesis and γ Enolase activity. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
Wortmannin indirectly inhibits γ Enolase through its modulation of the PI3K/AKT pathway. As a PI3K inhibitor, wortmannin impacts downstream signaling, influencing γ Enolase indirectly. This modulation can affect cellular processes associated with PI3K/AKT activation, highlighting a potential regulatory mechanism for γ Enolase. | ||||||