Date published: 2026-4-19

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G α o Activators

Santa Cruz Biotechnology now offers a broad range of G alpha o Activators for use in various applications. G alpha o Activators are compounds that modulate the activity of the G alpha o protein, a member of the G protein family involved in cellular signal transduction. These activators play a crucial role in research focused on understanding G protein-coupled receptor (GPCR) pathways, which are vital for transmitting signals from external stimuli into intracellular responses. The G alpha o subunit is particularly important in regulating neurotransmitter release and ion channel activity. By activating G alpha o proteins, researchers can study their effects on various cellular processes, including the regulation of calcium and potassium ion channels, which are essential for maintaining cellular homeostasis and communication. Moreover, G alpha o activators are instrumental in exploring the complexities of signal transduction networks, providing insights into how cells interpret and respond to different signals. The availability of G alpha o Activators enhances the ability of researchers to dissect the roles of G alpha o in cellular functions and its interactions within broader signaling networks. View detailed information on our available G alpha o Activators by clicking on the product name.

Items 1 to 10 of 11 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Mas7

145854-59-7sc-396179
1 mg
$184.00
(0)

Mas7 functions as a selective G alpha o modulator, exhibiting a unique ability to stabilize the active conformation of the G-protein. This stabilization enhances the exchange of GDP for GTP, leading to a more efficient activation of downstream signaling cascades. Its distinct structural features allow for specific interactions with membrane lipids, influencing membrane dynamics and receptor coupling. The compound's kinetic profile reveals a rapid onset of action, underscoring its potential to fine-tune cellular signaling mechanisms.

Dopamine

51-61-6sc-507336
1 g
$290.00
(0)

A neurotransmitter that activates the D2 receptor, which can couple with Gαo.

5-Carboxamidotryptamine maleate

74885-09-9sc-203477
sc-203477A
5 mg
25 mg
$302.00
$1086.00
2
(0)

A potent agonist for the 5-HT1 serotonin receptor.

Somatostatin Acetate

38916-34-6sc-220124
10 mg
$320.00
(0)

A specific peptide form of somatostatin that can activate sst receptors.

Adenosine

58-61-7sc-291838
sc-291838A
sc-291838B
sc-291838C
sc-291838D
sc-291838E
sc-291838F
1 g
5 g
100 g
250 g
1 kg
5 kg
10 kg
$34.00
$48.00
$300.00
$572.00
$1040.00
$2601.00
$4682.00
1
(0)

A purine nucleoside that can activate A1 receptors, which can be coupled with Gαo.

R-(+)-Baclofen (free base)

69308-37-8sc-203228
sc-203228A
10 mg
50 mg
$50.00
$195.00
(0)

A specific agonist for the GABAB receptor.

N-Acetyl-5-hydroxytryptamine

1210-83-9sc-202716
sc-202716A
10 mg
50 mg
$20.00
$104.00
(1)

An agonist for the MT2 melatonin receptor.

L(+)-2-Amino-4-phosphonobutanoic acid (L-AP4)

23052-81-5sc-200432
5 mg
$94.00
1
(1)

An agonist for mGluR4, a type of metabotropic glutamate receptor that can be coupled to Gαo.

Clonidine

4205-90-7sc-501519
100 mg
$240.00
1
(0)

A compound that acts as an agonist for alpha-2 adrenergic receptors.

LY 354740

176199-48-7sc-204064
sc-204064A
10 mg
50 mg
$266.00
$886.00
2
(1)

An agonist for mGluR2 and mGluR3, which belong to the Group II metabotropic glutamate receptors and can couple with Gαi/o proteins.