FRP-2 Inhibitors
Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
4-(6-(4-(Piperazin-1-yl)phenyl)pyrazolo[1,5-a]pyrimidin-3-yl)quinoline | 1062368-24-4 | sc-476297 | 5 mg | $240.00 | ||
Inhibits BMP signaling by targeting ALK2, thereby indirectly modulating FRP-2 as BMP signaling is intricately linked to FRP-2 expression and function. | ||||||
XAV939 | 284028-89-3 | sc-296704 sc-296704A sc-296704B | 1 mg 5 mg 50 mg | $35.00 $115.00 $515.00 | 26 | |
Suppresses Wnt signaling by inhibiting tankyrase activity, leading to the stabilization of Axin, a key regulator of the Wnt pathway. This stabilization indirectly influences FRP-2 modulation. | ||||||
LY2090314 | 603288-22-8 | sc-507359 | 5 mg | $175.00 | ||
Inhibits GSK-3, a critical regulator of Wnt signaling, leading to the modulation of downstream targets, including FRP-2, within the Wnt pathway. | ||||||
SIS3 hydrochloride | 521984-48-5 | sc-253565 | 5 mg | $334.00 | 2 | |
Selectively inhibits the TGF-β/Smad3 pathway, indirectly influencing FRP-2 expression, as TGF-β pathways cross-talk with Wnt pathways, where FRP-2 is known to play a role. | ||||||
Bemcentinib | 1037624-75-1 | sc-507363 | 10 mg | $900.00 | ||
Targets Axl, affecting multiple signaling pathways, including the Wnt pathway. This compound indirectly modulates FRP-2 by altering the intricate crosstalk between Axl and Wnt signaling. | ||||||
JNK Inhibitor VIII | 894804-07-0 | sc-202673 | 5 mg | $267.00 | 2 | |
Inhibits c-Jun N-terminal kinase (JNK), disrupting the MAPK pathway. As MAPK signaling intersects with Wnt pathways, this inhibitor indirectly influences FRP-2 expression and function. | ||||||
SB 431542 | 301836-41-9 | sc-204265 sc-204265A sc-204265B | 1 mg 10 mg 25 mg | $80.00 $212.00 $408.00 | 48 | |
Targets the TGF-β receptor, affecting TGF-β signaling, which is interconnected with Wnt pathways. This compound indirectly modulates FRP-2 by altering the crosstalk between TGF-β and Wnt signaling. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $182.00 $693.00 | 88 | |
Inhibits ROCK, impacting cytoskeletal dynamics and cellular morphology, indirectly influencing FRP-2 as ROCK is implicated in the regulation of various signaling pathways, including Wnt. | ||||||
SAG | 912545-86-9 | sc-212905 sc-212905A | 1 mg 5 mg | $163.00 $413.00 | 27 | |
Activates Hedgehog signaling, which crosstalks with Wnt pathways. As FRP-2 is linked to Wnt signaling, modulating Hedgehog indirectly influences FRP-2 expression and function. | ||||||
AZD8055 | 1009298-09-2 | sc-364424 sc-364424A | 10 mg 50 mg | $160.00 $345.00 | 12 | |
Inhibits mTOR, a central regulator of multiple signaling pathways, including Wnt. This compound indirectly influences FRP-2 expression and function through the modulation of mTOR-controlled pathways. | ||||||