FMR1NB Inhibitors
Items 1 to 10 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
LY294002 is a potent inhibitor of PI3K, a kinase involved in signaling pathways linked to protein synthesis regulation. FMR1NB, when functionally active, associates with certain mRNAs and regulates their translation. PI3K inhibition could lead to reduced protein synthesis, indirectly inhibiting FMR1NB-associated translation processes. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $90.00 $349.00 | 284 | |
SB203580 is a specific inhibitor of p38 MAPK. The p38 MAPK signaling pathway is involved in the regulation of protein translation and cellular stress responses. By inhibiting p38 MAPK, SB203580 could reduce the translation of proteins, including those associated with FMR1NB function. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
Rapamycin is an mTOR inhibitor which impacts protein synthesis. Since FMR1NB is known to be involved in the regulation of protein translation, inhibiting mTOR with rapamycin could reduce the protein translation process that FMR1NB regulates. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $64.00 $246.00 | 136 | |
U0126 is an inhibitor of MEK, which is part of the ERK/MAPK pathway. This pathway is implicated in the control of protein synthesis and cellular proliferation. Inhibition of MEK could disrupt downstream signaling, potentially inhibiting protein translation processes involving FMR1NB. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $67.00 $223.00 $425.00 | 97 | |
Wortmannin is a potent PI3K inhibitor, like LY294002, and would similarly disrupt PI3K-dependent signaling pathways, which could indirectly inhibit the protein synthesis regulatory function of FMR1NB. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
PD98059 selectively inhibits MEK, which is upstream of ERK in the MAPK pathway. By inhibiting MEK, PD98059 could interfere with protein synthesis regulation, potentially inhibiting processes in which FMR1NB is involved. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
SP600125 is an inhibitor of JNK, which is involved in stress response signaling pathways. As stress responses can regulate protein synthesis, inhibiting JNK could indirectly affect the function of FMR1NB in this context. | ||||||
Roscovitine | 186692-46-6 | sc-24002 sc-24002A | 1 mg 5 mg | $94.00 $265.00 | 42 | |
Roscovitine is an inhibitor of cyclin-dependent kinases (CDKs) which are involved in cell cycle regulation. CDK inhibition could indirectly affect cellular processes related to protein synthesis and thus inhibit FMR1NB function. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin has been shown to affect multiple signaling pathways, including those related to the inflammatory response and protein synthesis. Its broad-spectrum activity could potentially inhibit processes in which FMR1NB is functionally involved. | ||||||
Cycloheximide | 66-81-9 | sc-3508B sc-3508 sc-3508A | 100 mg 1 g 5 g | $41.00 $84.00 $275.00 | 127 | |
Cycloheximide inhibits eukaryotic protein synthesis by interfering with the translocation step in protein elongation. This inhibition could reduce overall protein synthesis, including that regulated by FMR1NB. | ||||||