FLJ36031 Activators
FLJ36031 activators constitute a chemical class designed to interact with the molecular biology of cells via the modulation of specific proteins encoded by the FLJ36031 gene. This particular class of chemicals is characterized by its ability to bind to and activate the protein product of FLJ36031, often resulting in a cascade of intracellular events. The binding affinity and specificity of these activators are fundamental to their function, as the precise interaction with the target protein is critical for the subsequent biological response. The chemistry of FLJ36031 activators is diverse, with molecules in this class possessing a range of structural motifs and functional groups that enable them to engage with their target. These variations in chemical structure allow for fine-tuning of the activators' properties, such as solubility, stability, and specificity, which are crucial for their interaction with the FLJ36031 protein.
The development and characterization of FLJ36031 activators involve a multidisciplinary approach that combines aspects of organic chemistry, biochemistry, and molecular biology. The design of these compounds is often driven by the structure-activity relationship (SAR) studies, which explore how modifications in the chemical structure can impact the interaction with the target protein. Advanced analytical techniques, including mass spectrometry, nuclear magnetic resonance (NMR) spectroscopy, and X-ray crystallography, are commonly employed to elucidate the structure of these activators and their complexes with the FLJ36031 protein. Additionally, computational methods such as molecular docking and molecular dynamics simulations play an integral role in predicting how these activators might interact with their target at the atomic level. The data gathered from these approaches are instrumental in advancing the understanding of the molecular mechanisms by which FLJ36031 activators engage with and modulate the function of the associated protein.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin increases intracellular cyclic AMP (cAMP) by activating adenylyl cyclase, leading to the activation of protein kinase A (PKA). PKA can then phosphorylate target proteins, possibly including FLJ36031, thus enhancing its activity. | ||||||
D-erythro-Sphingosine-1-phosphate | 26993-30-6 | sc-201383 sc-201383D sc-201383A sc-201383B sc-201383C | 1 mg 2 mg 5 mg 10 mg 25 mg | $165.00 $322.00 $570.00 $907.00 $1727.00 | 7 | |
Sphingosine-1-phosphate interacts with its G protein-coupled receptors to activate intracellular signaling pathways, such as PI3K/Akt, potentially resulting in the activation of downstream targets, including FLJ36031. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
PMA is a potent activator of protein kinase C (PKC), which phosphorylates a wide range of cellular proteins. Through this mechanism, PMA could lead to the activation of signaling pathways that include FLJ36031 as a key regulatory component. | ||||||
Ionomycin | 56092-82-1 | sc-3592 sc-3592A | 1 mg 5 mg | $78.00 $270.00 | 80 | |
Ionomycin is a calcium ionophore that increases intracellular calcium levels, activating calcium-dependent protein kinases and signaling cascades that could enhance the functional activity of FLJ36031. | ||||||
FTY720 | 162359-56-0 | sc-202161 sc-202161A sc-202161B | 1 mg 5 mg 25 mg | $33.00 $77.00 $120.00 | 14 | |
FTY720 is a sphingosine-1-phosphate receptor modulator which, after phosphorylation, can influence a variety of signaling pathways, potentially leading to the activation of signaling molecules including FLJ36031. | ||||||
Isoproterenol Hydrochloride | 51-30-9 | sc-202188 sc-202188A | 100 mg 500 mg | $28.00 $38.00 | 5 | |
Isoproterenol is a non-selective beta-adrenergic receptor agonist that increases cAMP levels in cells, which in turn can activate PKA and potentially result in the activation of FLJ36031. | ||||||
8-Bromo-cAMP | 76939-46-3 | sc-201564 sc-201564A | 10 mg 50 mg | $126.00 $328.00 | 30 | |
8-Bromo-cAMP is a cell-permeable cAMP analog that activates PKA, leading to the phosphorylation and potential activation of target proteins, possibly including FLJ36031. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
EGCG is a polyphenol that has been shown to inhibit a variety of protein kinases, altering signaling pathways and potentially resulting in the activation of proteins functionally linked to these pathways, such as FLJ36031. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
LY294002 is a PI3K inhibitor which, while primarily known to inhibit the PI3K/Akt pathway, could indirectly result in the activation of alternate signaling pathways that may involve FLJ36031. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $64.00 $246.00 | 136 | |
U0126 is an inhibitor of MEK1/2, which could lead to a shift in signaling dynamics and potentially enhance signaling pathways that activate FLJ36031. | ||||||