Fli-1 Inhibitors
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Etoposide (VP-16) | 33419-42-0 | sc-3512B sc-3512 sc-3512A | 10 mg 100 mg 500 mg | $51.00 $231.00 $523.00 | 63 | |
Inhibits FLI-1 expression by promoting its degradation and reducing its transcriptional activity, impacting cell proliferation and tumorigenesis. | ||||||
Rocaglamide | 84573-16-0 | sc-203241 sc-203241A sc-203241B sc-203241C sc-203241D | 100 µg 1 mg 5 mg 10 mg 25 mg | $275.00 $474.00 $1639.00 $2497.00 $5344.00 | 4 | |
Downregulates FLI-1 expression by inhibiting its transcription and disrupting protein translation, leading to decreased cell proliferation and tumor growth. | ||||||
(±)-JQ1 | 1268524-69-1 | sc-472932 sc-472932A | 5 mg 25 mg | $231.00 $863.00 | 1 | |
Competitively binds to BRD4, blocking its interaction with FLI-1, resulting in decreased FLI-1-mediated transcription and impaired tumor cell growth in Ewing sarcoma. | ||||||
Saracatinib | 379231-04-6 | sc-364607 sc-364607A | 10 mg 200 mg | $115.00 $1056.00 | 7 | |
Inhibits FLI-1 through its Src kinase inhibition, downregulating FLI-1 expression and attenuating its oncogenic signaling, reducing cancer cell proliferation. | ||||||
N-([1,1′-Biphenyl]-4-ylmethyl)-6-phenyl-3-(pyridin-2-yl)-1,2,4-triazin-5-amine | 1357171-62-0 | sc-503580 | 1 mg | $245.00 | ||
Disrupts the binding of FLI-1 to its target DNA sequences, inhibiting its transcriptional activity and reducing cell proliferation and tumorigenesis. | ||||||
A 419259 trihydrochloride | 1435934-25-0 | sc-361094 | 5 mg | $213.00 | 6 | |
Selectively inhibits FLI-1, preventing its DNA binding and transcriptional activation, leading to reduced tumor cell growth and metastasis in Ewing sarcoma. | ||||||
Docosa-4Z,7Z,10Z,13Z,16Z,19Z-hexaenoic Acid (22:6, n-3) | 6217-54-5 | sc-200768 sc-200768A sc-200768B sc-200768C sc-200768D | 100 mg 1 g 10 g 50 g 100 g | $94.00 $210.00 $1779.00 $8021.00 $16657.00 | 11 | |
Downregulates FLI-1 expression in Ewing sarcoma cells, leading to diminished cell proliferation and metastatic potential, potentially affecting tumor progression. | ||||||
(+)-Nutlin-3 | 675576-97-3 | sc-222085 sc-222085A | 500 µg 1 mg | $94.00 $122.00 | ||
Disrupts the interaction between FLI-1 and MDM2, stabilizing FLI-1 and promoting its degradation, resulting in reduced FLI-1 transcriptional activity and tumor growth. | ||||||
GSK-3 Inhibitor IX | 667463-62-9 | sc-202634 sc-202634A sc-202634B | 1 mg 10 mg 50 mg | $58.00 $188.00 $884.00 | 10 | |
Inhibits glycogen synthase kinase 3 (GSK-3), leading to reduced phosphorylation and activation of FLI-1, attenuating its oncogenic function in Ewing sarcoma. | ||||||