FIT2 Activators
FIT2 Activators are a selection of chemical compounds that enhance the functional activity of FIT2, a protein involved in lipid droplet formation and fat storage. Monounsaturated fatty acids like Palmitoleic acid and Oleic acid serve as substrates for triglyceride synthesis, directly supporting the lipid storage role of FIT2. Linoleic acid, an essential fatty acid, similarly contributes to the lipid droplet formation process, which is central to FIT2's function. Omega-3 fatty acids such as Eicosapentaenoic acid (EPA) and Docosahexaenoic acid (DHA) influence lipid metabolism in a way that may promote the storage capacity of FIT2, enhancing its activity in creating and maintaining lipid droplets. Phytosphingosine, with its role in modifying cellular lipid membranes, could indirectly support FIT2's ability to manage lipid storage, while PPAR agonists like Pioglitazone and Rosiglitazone can augment fat storage mechanisms, potentially increasing the demand for FIT2's lipid droplet formation function.
Furthermore, Fenofibrate activates PPARα, which could lead to an enhanced need for FIT2's lipid storage capabilities as part of broader lipid metabolism. Insulin is a potent activator of lipid synthesis and storage, potentially upregulating FIT2 function by increasing the intracellular availability of lipids. GlucoseFIT2 Activators encompass a set of chemical compounds known to augment the functional activity of fat storage-inducing transmembrane protein 2 (FIT2) through their individual effects on lipid metabolism and storage processes. Fatty acids such as Palmitoleic acid, Oleic acid, and Linoleic acid are key substrates for the biosynthesis of triglycerides, which FIT2 is involved in storing within lipid droplets, thereby directly enhancing FIT2's lipid storage capacity. The omega-3 fatty acids Eicosapentaenoic acid (EPA) and Docosahexaenoic acid (DHA) are integrated into cellular lipid pools, and their presence is thought to promote the functional activity of FIT2 in lipid droplet formation. Phytosphingosine's role in membrane lipid composition could lend support to FIT2's function in organizing lipid storage structures, while the PPARγ agonists, Pioglitazone and Rosiglitazone, are known to stimulate adipogenesis and lipid accumulation, which could indirectly upregulate FIT2's activity in lipid droplet biogenesis.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Palmitoleic acid | 373-49-9 | sc-205424 sc-205424A sc-205424B sc-205424C sc-205424D | 100 mg 500 mg 1 g 5 g 10 g | $32.00 $132.00 $233.00 $1019.00 $1870.00 | 4 | |
A monounsaturated fatty acid that can be incorporated into triglycerides stored by FIT2. Its presence can enhance the lipid droplet formation function of FIT2. | ||||||
Oleic Acid | 112-80-1 | sc-200797C sc-200797 sc-200797A sc-200797B | 1 g 10 g 100 g 250 g | $36.00 $102.00 $569.00 $1173.00 | 10 | |
Another monounsaturated fatty acid that directly contributes to lipid droplet formation, potentially enhancing the functional activity of FIT2 by providing substrate. | ||||||
Linoleic Acid | 60-33-3 | sc-200788 sc-200788A sc-200788B sc-200788C | 100 mg 1 g 5 g 25 g | $33.00 $63.00 $163.00 $275.00 | 4 | |
An essential polyunsaturated fatty acid that can be esterified into storage lipids, possibly facilitating the lipid storage function of FIT2. | ||||||
Eicosa-5Z,8Z,11Z,14Z,17Z-pentaenoic Acid (20:5, n-3) | 10417-94-4 | sc-200766 sc-200766A | 100 mg 1 g | $102.00 $423.00 | ||
This omega-3 fatty acid may influence lipid metabolism, indirectly enhancing the lipid storage function of FIT2. | ||||||
Docosa-4Z,7Z,10Z,13Z,16Z,19Z-hexaenoic Acid (22:6, n-3) | 6217-54-5 | sc-200768 sc-200768A sc-200768B sc-200768C sc-200768D | 100 mg 1 g 10 g 50 g 100 g | $92.00 $206.00 $1744.00 $7864.00 $16330.00 | 11 | |
An omega-3 fatty acid known to be incorporated into phospholipids, which could support the functional activity of FIT2 in lipid handling and storage. | ||||||
Phytosphingosine | 554-62-1 | sc-201385 sc-201385A | 5 mg 25 mg | $100.00 $419.00 | 4 | |
A sphingolipid that can affect the lipid composition of cellular membranes, potentially enhancing the FIT2 activity in lipid droplet formation. | ||||||
Pioglitazone | 111025-46-8 | sc-202289 sc-202289A | 1 mg 5 mg | $54.00 $123.00 | 13 | |
A peroxisome proliferator-activated receptor gamma (PPARγ) agonist that can promote lipid storage, potentially influencing FIT2's function in lipid droplet biogenesis. | ||||||
Rosiglitazone | 122320-73-4 | sc-202795 sc-202795A sc-202795C sc-202795D sc-202795B | 25 mg 100 mg 500 mg 1 g 5 g | $118.00 $320.00 $622.00 $928.00 $1234.00 | 38 | |
Another PPARγ agonist that may enhance the storage of lipids, indirectly augmenting the activity of FIT2. | ||||||
Fenofibrate | 49562-28-9 | sc-204751 | 5 g | $40.00 | 9 | |
A PPARα agonist that can influence lipid metabolism, possibly enhancing the functional activity of FIT2 by increasing the demand for intracellular lipid storage. | ||||||
Insulin | 11061-68-0 | sc-29062 sc-29062A sc-29062B | 100 mg 1 g 10 g | $153.00 $1224.00 $12239.00 | 82 | |
Enhances lipid synthesis and storage, which could upregulate FIT2 activity as part of the lipogenic pathway. | ||||||