Date published: 2025-12-18

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FIH-1 Antibodies

Santa Cruz Biotechnology delivers a wide array of FIH-1 monoclonal antibodies for research focused on understanding FIH-1's role in cellular processes. The monoclonal antibodies are validated for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). FIH-1, or Factor Inhibiting HIF-1, functions as a key regulator of the hypoxia-inducible factor (HIF) pathway, playing a significant role in cellular responses to low oxygen levels. Through hydroxylation of HIF-1α, FIH-1 modulates its activity and stability, influencing processes such as angiogenesis, metabolism, and cell survival. Research into FIH-1 continues to reveal its implications in various diseases, including cancer and ischemic conditions. Scientists can explore the complex interactions between FIH-1 and its molecular partners using specific detection methods. Understanding FIH-1's regulatory mechanisms provides valuable insights into cellular adaptation to hypoxic conditions. Investigating FIH-1's role in disease progression helps identify potential therapeutic targets. Santa Cruz Biotechnology monoclonal antibodies enable researchers to advance scientific understanding of hypoxia signaling pathways and their impact on human health.

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FIH-1 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

FIH-1 Antibody (A-5)

sc-271780mouse IgG2a κ15-243 (h)WB, IP, IF, IHC(P), ELISAm, r, h
7
(6)

FIH-1 Antibody (D-12)

sc-365016mouse IgG1 κ15-243 (h)WB, IP, IF, ELISAm, r, h

new

(3)

FIH-1 Antibody (F-11)

sc-365128mouse IgG2b κ15-243 (h)WB, IP, IF, ELISAm, r, h

new

(3)

FIH-1 CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

FIH-1 CRISPR/Cas9 KO Plasmid (h)

sc-402511hGene KnockoutGFP0
(0)

FIH-1 HDR Plasmid (h)

sc-402511-HDRhHomology Directed RepairPuromycin0
(0)

FIH-1 Double Nickase Plasmid (h)

sc-402511-NIChGene KnockoutPuromycin0
(0)

FIH-1 Double Nickase Plasmid (h2)

sc-402511-NIC-2hGene KnockoutPuromycin0
(0)

FIH-1 CRISPR/Cas9 KO Plasmid (m)

sc-435640mGene KnockoutGFP0
(0)

FIH-1 HDR Plasmid (m)

sc-435640-HDRmHomology Directed RepairPuromycin0
(0)

FIH-1 Double Nickase Plasmid (m)

sc-435640-NICmGene KnockoutPuromycin0
(0)

FIH-1 Double Nickase Plasmid (m2)

sc-435640-NIC-2mGene KnockoutPuromycin0
(0)

FIH-1 CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

FIH-1 CRISPR Activation Plasmid (h)

sc-402511-ACThGene ActivationPuro, Blast, Hygro0
(0)

FIH-1 CRISPR Activation Plasmid (h2)

sc-402511-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

FIH-1 Lentiviral Activation Particles (h)

sc-402511-LAChGene ActivationPuro, Blast, Hygro0
(0)

FIH-1 Lentiviral Activation Particles (h2)

sc-402511-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

FIH-1 CRISPR Activation Plasmid (m)

sc-435640-ACTmGene ActivationPuro, Blast, Hygro0
(0)

FIH-1 CRISPR Activation Plasmid (m2)

sc-435640-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

FIH-1 Lentiviral Activation Particles (m)

sc-435640-LACmGene ActivationPuro, Blast, Hygro0
(0)

FIH-1 Lentiviral Activation Particles (m2)

sc-435640-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

FIH-1 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

FIH-1 siRNA (h)

sc-37885hGene SilencingN/A
1
(0)

FIH-1 shRNA Plasmid (h)

sc-37885-SHhGene SilencingPuromycin
1
(0)

FIH-1 shRNA (h) Lentiviral Particles

sc-37885-VhGene SilencingPuromycin
1
(0)

FIH-1 siRNA (m)

sc-37886mGene SilencingN/A
1
(0)

FIH-1 shRNA Plasmid (m)

sc-37886-SHmGene SilencingPuromycin
1
(0)

FIH-1 shRNA (m) Lentiviral Particles

sc-37886-VmGene SilencingPuromycin
1
(0)