Date published: 2025-12-19

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Fibrosin-like 1 Inhibitors

Chemical inhibitors of Fibrosin-like 1 can play a crucial role in regulating its activity through various signaling pathways within the cell. Staurosporine, a well-known protein kinase inhibitor, can lead to a reduction in phosphorylation events, which are essential for Fibrosin-like 1's activity. Similarly, Wortmannin and LY294002 are both inhibitors of phosphoinositide 3-kinases (PI3K), and their action can diminish the activity of downstream effectors involved in regulating Fibrosin-like 1. Rapamycin, an mTOR inhibitor, can disrupt central processes in cell growth and metabolism that may intersect with Fibrosin-like 1's function. Moreover, SB203580 targets p38 MAP Kinase, involved in inflammatory responses and cell differentiation, which could have a significant impact on Fibrosin-like 1's role within these biological processes. Additionally, U0126 and PD98059, both MEK inhibitors, can lead to reduced ERK pathway activity, which is a key pathway for cell proliferation and differentiation that Fibrosin-like 1 may influence. SP600125, an inhibitor of JNK, interferes with stress response pathways that can affect Fibrosin-like 1's regulatory roles. Dasatinib, with its broad-spectrum inhibition of tyrosine kinases, can affect multiple signaling pathways, potentially altering Fibrosin-like 1's activity. PP2, a selective inhibitor of Src family tyrosine kinases, can also disrupt signaling pathways crucial for Fibrosin-like 1's activity. Furthermore, Lestaurtinib and Sunitinib, inhibitors of various tyrosine kinases including JAK2, FLT3, TRK, VEGFR, and PDGFR, can impede signaling cascades that are essential for the activity of Fibrosin-like 1, further influencing its function within the cell.

Items 1 to 10 of 12 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Staurosporine

62996-74-1sc-3510
sc-3510A
sc-3510B
100 µg
1 mg
5 mg
$82.00
$150.00
$388.00
113
(4)

Staurosporine is a potent inhibitor of protein kinases, which are essential for various signaling pathways. Inhibition of these kinases by Staurosporine can lead to a decrease in phosphorylation events that are necessary for the activity of Fibrosin-like 1.

Wortmannin

19545-26-7sc-3505
sc-3505A
sc-3505B
1 mg
5 mg
20 mg
$66.00
$219.00
$417.00
97
(3)

Wortmannin inhibits phosphoinositide 3-kinases (PI3K), which are upstream in cell survival and growth pathways. PI3K inhibition can reduce the activity of downstream effectors that are likely to be involved in the regulation or stabilization of Fibrosin-like 1 function.

LY 294002

154447-36-6sc-201426
sc-201426A
5 mg
25 mg
$121.00
$392.00
148
(1)

LY294002 is another PI3K inhibitor, similar to Wortmannin, and it can hinder the PI3K/AKT pathway, potentially leading to decreased activity of pathways that Fibrosin-like 1 may be involved in, thus functionally inhibiting Fibrosin-like 1.

Rapamycin

53123-88-9sc-3504
sc-3504A
sc-3504B
1 mg
5 mg
25 mg
$62.00
$155.00
$320.00
233
(4)

Rapamycin selectively inhibits mTOR (mechanistic target of rapamycin), which is a central molecule in regulating cell growth and metabolism. Inhibition of mTOR can disrupt activities and pathways that Fibrosin-like 1 is involved in, leading to its functional inhibition.

SB 203580

152121-47-6sc-3533
sc-3533A
1 mg
5 mg
$88.00
$342.00
284
(5)

SB203580 specifically inhibits p38 MAP Kinase, which is involved in inflammatory responses and cell differentiation. Inhibition of p38 MAPK might disrupt signaling pathways that are crucial for the functional activity of Fibrosin-like 1.

U-0126

109511-58-2sc-222395
sc-222395A
1 mg
5 mg
$63.00
$241.00
136
(2)

U0126 is an inhibitor of MEK, which is upstream of the ERK pathway, a key pathway for cell proliferation and differentiation. Inhibition of MEK can lead to reduced ERK activity, indirectly leading to functional inhibition of Fibrosin-like 1.

SP600125

129-56-6sc-200635
sc-200635A
10 mg
50 mg
$40.00
$150.00
257
(3)

SP600125 inhibits JNK (c-Jun N-terminal kinase), which is implicated in stress responses and apoptosis. By inhibiting JNK, SP600125 might interfere with signaling pathways that Fibrosin-like 1 is a part of, resulting in its functional inhibition.

Dasatinib

302962-49-8sc-358114
sc-358114A
25 mg
1 g
$47.00
$145.00
51
(1)

Dasatinib is a broad-spectrum tyrosine kinase inhibitor, which can inhibit Src family kinases and other kinases, potentially affecting multiple signaling pathways that could be involved in the regulation of Fibrosin-like 1 function, leading to its inhibition.

PP 2

172889-27-9sc-202769
sc-202769A
1 mg
5 mg
$92.00
$223.00
30
(1)

PP2 is a selective inhibitor of Src family tyrosine kinases. By inhibiting Src kinases, PP2 can disrupt signaling pathways that may be essential for the activity of Fibrosin-like 1, therefore functionally inhibiting it.

PD 98059

167869-21-8sc-3532
sc-3532A
1 mg
5 mg
$39.00
$90.00
212
(2)

PD98059 selectively inhibits MEK, which is upstream of the ERK pathway. By inhibiting MEK, PD98059 can reduce ERK signaling, which may play a role in pathways involving Fibrosin-like 1, leading to its functional inhibition.