The chemical class referred to as FHR-2 Activators denotes a specific category of compounds identified for their ability to modulate the activity of the FHR-2 gene. FHR-2, or Factor H-Related Protein 2, is a gene encoding a protein that belongs to the factor H family of complement regulatory proteins. These proteins are involved in regulating the complement system, a part of the immune system responsible for recognizing and eliminating pathogens. While the precise function of FHR-2 is not fully elucidated, it is believed to play a role in modulating the activity of the complement system, potentially influencing immune responses and inflammatory processes. Activators of FHR-2 are substances capable of enhancing the expression or function of this gene, potentially influencing downstream cellular pathways and biological responses associated with its activity.
Characterizing compounds as FHR-2 Activators typically involves comprehensive screening processes aimed at evaluating their ability to interact with regulatory elements of the FHR-2 gene or modulate the activity of proteins associated with its expression or function. These activators may operate through diverse mechanisms, such as binding to specific DNA sequences within the gene promoter region, regulating the activity of transcription factors responsible for FHR-2 gene expression, or modulating post-translational modifications of the FHR-2 protein. Understanding the molecular mechanisms underlying FHR-2 activation by these compounds is crucial for elucidating the roles of FHR-2 in immune regulation and inflammatory responses. Further research into FHR-2 Activators may provide insights into novel cellular pathways and contribute to a deeper understanding of FHR-2's function in immune system modulation.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin may modulate NF-κB signaling, a pathway known to regulate the expression of various genes involved in immune responses. | ||||||
Cholecalciferol | 67-97-0 | sc-205630 sc-205630A sc-205630B | 1 g 5 g 10 g | $71.00 $163.00 $296.00 | 2 | |
Through its active metabolite, it can bind to the vitamin D receptor, potentially influencing the transcription of immune-related genes. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
A metabolite of vitamin A that binds retinoic acid receptors and can regulate gene expression, including in immune system pathways. | ||||||
1α,25-Dihydroxyvitamin D3 | 32222-06-3 | sc-202877B sc-202877A sc-202877C sc-202877D sc-202877 | 50 µg 1 mg 5 mg 10 mg 100 µg | $220.00 $645.00 $1000.00 $1500.00 $440.00 | 32 | |
The active form of vitamin D3, it may stimulate the vitamin D receptor, potentially influencing the expression of genes related to the immune system. | ||||||
Zinc | 7440-66-6 | sc-213177 | 100 g | $48.00 | ||
Zinc can influence the immune system and may affect the transcription of various immune-related genes. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
May modulate sirtuin activity and NF-κB signaling, potentially influencing the expression of genes in immune pathways. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $153.00 $292.00 $489.00 $1325.00 $8465.00 $933.00 | 22 | |
Can activate Nrf2, potentially leading to changes in the expression of genes associated with oxidative stress response and possibly the immune system. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $31.00 $47.00 $84.00 $222.00 | 19 | |
A short-chain fatty acid that can act as a histone deacetylase inhibitor, potentially affecting chromatin structure and gene expression. | ||||||
Lycopene | 502-65-8 | sc-205738 sc-205738A sc-205738B | 1 mg 5 mg 1 g | $146.00 $582.00 $6248.00 | 4 | |
An antioxidant that can modulate immune responses, potentially influencing the transcription of genes within the immune system. | ||||||