Fascin 1 Activators
Fascin 1 Activators refer to a class of chemical compounds that play a crucial role in modulating the activity of the protein fascin 1. Fascin 1 is a cytoskeletal protein primarily found in animal cells, and it is well-known for its essential functions in organizing actin filaments into bundles, which are vital for maintaining cell shape, migration, and adhesion. Fascin 1 is particularly abundant in various types of cells, including neurons, muscle cells, and certain cancer cells. The activation of fascin 1 is crucial for its role in regulating cellular processes that require dynamic changes in the actin cytoskeleton.
Chemical compounds classified as Fascin 1 Activators are designed to interact with and modulate the activity of fascin 1. These activators typically work by binding to fascin 1 and inducing conformational changes or post-translational modifications that enhance its bundling activity toward actin filaments. This increased bundling activity can have profound effects on cell behavior, influencing processes such as cell migration, tissue development, and the formation of specialized cellular structures. Researchers are actively exploring these activators to gain a deeper understanding of their mechanisms of action and their applications in various cellular and biological contexts.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Retinoic acid regulates gene expression through retinoid receptors, which can upregulate Fascin 1 in certain cell types during differentiation. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $40.00 $129.00 $210.00 $490.00 $929.00 | 119 | |
PMA activates protein kinase C (PKC) which can lead to the induction of Fascin 1 expression through signaling cascades that alter cytoskeletal dynamics. | ||||||
Hydrogen Peroxide | 7722-84-1 | sc-203336 sc-203336A sc-203336B | 100 ml 500 ml 3.8 L | $30.00 $60.00 $93.00 | 27 | |
As an oxidative stress agent, H2O2 can activate several signaling pathways that potentially increase Fascin 1 expression as part of the cellular stress response. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $76.00 $82.00 $367.00 | 36 | |
Dexamethasone acts through glucocorticoid receptors, which may upregulate Fascin 1 expression in certain contexts of inflammation and immune response. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Lithium chloride can inhibit GSK-3β, leading to Wnt pathway activation which may result in increased Fascin 1 expression associated with cell motility. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Forskolin activates adenylate cyclase and raises cAMP levels, which can lead to the induction of Fascin 1 expression through the cAMP response element-binding protein (CREB). | ||||||
5-Aza-2′-Deoxycytidine | 2353-33-5 | sc-202424 sc-202424A sc-202424B | 25 mg 100 mg 250 mg | $214.00 $316.00 $418.00 | 7 | |
This compound inhibits DNA methyltransferases, potentially causing the re-expression of Fascin 1 if its gene was silenced by hypermethylation. | ||||||
Doxorubicin | 23214-92-8 | sc-280681 sc-280681A | 1 mg 5 mg | $173.00 $418.00 | 43 | |
Doxorubicin can increase Fascin 1 expression as a cellular response to DNA damage or as a part of the stress response pathways. | ||||||