FAM9B Inhibitors
Items 1 to 10 of 12 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $153.00 $396.00 | 113 | |
Staurosporine is a potent inhibitor of protein kinases. The kinase activity influenced by staurosporine can lead to the inhibition of FAM9B by preventing its phosphorylation, which is required for its function. | ||||||
Bisindolylmaleimide I (GF 109203X) | 133052-90-1 | sc-24003A sc-24003 | 1 mg 5 mg | $105.00 $242.00 | 36 | |
Bisindolylmaleimide I is a specific inhibitor of protein kinase C (PKC). PKC is known to phosphorylate a variety of proteins, and its inhibition can result in the reduced phosphorylation and subsequent inhibition of FAM9B function. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
LY294002 is a phosphoinositide 3-kinase (PI3K) inhibitor. By inhibiting PI3K, it prevents the activation of downstream signaling pathways that are necessary for FAM9B activation, thereby inhibiting FAM9B function. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
PD98059 is an inhibitor of MAP kinase kinase (MEK), which is involved in the MAPK/ERK pathway. Inhibition of MEK prevents the activation of downstream ERK, which could be necessary for FAM9B function, thereby inhibiting its activity. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $64.00 $246.00 | 136 | |
U0126 is another MEK inhibitor with a similar mechanism of action to PD98059, preventing the activation of ERK and potentially leading to the inhibition of FAM9B function as a result. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
SP600125 is a selective inhibitor of c-Jun N-terminal kinase (JNK). Inhibition of JNK can lead to the inhibition of FAM9B by preventing the phosphorylation and activation that JNK signaling contributes to. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $90.00 $349.00 | 284 | |
SB203580 is a selective inhibitor of p38 MAP kinase. By preventing p38 MAP kinase activity, it can inhibit the phosphorylation and activation of downstream targets, potentially including FAM9B. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $67.00 $223.00 $425.00 | 97 | |
Wortmannin is a potent inhibitor of PI3K. Similar to LY294002, by inhibiting PI3K, it disrupts the PI3K/AKT pathway, which could be crucial for FAM9B activation, thus leading to its inhibition. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
Rapamycin inhibits the mTOR pathway, which is downstream of PI3K/AKT signaling. Inhibition of mTOR can result in the decreased activity of proteins that are regulated by this pathway, including FAM9B. | ||||||
PP 2 | 172889-27-9 | sc-202769 sc-202769A | 1 mg 5 mg | $94.00 $227.00 | 30 | |
PP2 is a selective inhibitor of Src family tyrosine kinases. By inhibiting Src kinases, it can prevent the phosphorylation and activation of FAM9B if Src kinase activity is necessary for FAM9B function. | ||||||