Date published: 2026-4-1

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FAM86A Inhibitors

FAM86A inhibitors are a class of chemical compounds designed to specifically target and inhibit the function of the FAM86A protein, a member of the FAM86 family of proteins whose functions are not yet fully characterized. The FAM86 family is a group of proteins that have been identified through genomic studies, but their biological roles remain largely unexplored. FAM86A, like other members of this family, is believed to be involved in cellular processes related to protein interaction networks, potentially playing a role in the regulation of cellular signaling, protein synthesis, or other essential cellular functions. The inhibition of FAM86A by these compounds provides a tool for researchers to study the specific functions of this protein and its impact on cellular physiology. The mechanism by which FAM86A inhibitors exert their effects typically involves binding to the active site or other critical regions of the FAM86A protein, thereby blocking its interaction with other cellular components or preventing it from carrying out its biological functions. This inhibition can disrupt the normal activity of FAM86A, leading to changes in the cellular processes it regulates. Since FAM86A's precise function is not well understood, inhibiting this protein allows researchers to observe the resulting cellular effects, which can provide insights into its role in the cell. For example, inhibition may affect protein-protein interactions, signal transduction pathways, or other cellular mechanisms in which FAM86A is involved. Understanding the function of FAM86A and the impact of its inhibition is essential for uncovering the broader roles of this protein family in cellular biology and for understanding how these proteins contribute to the maintenance of cellular homeostasis and function.

Items 1 to 10 of 12 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Wortmannin

19545-26-7sc-3505
sc-3505A
sc-3505B
1 mg
5 mg
20 mg
$67.00
$223.00
$425.00
97
(3)

Wortmannin is a steroidal metabolite that selectively inhibits PI3K, which is a part of the AKT signaling pathway, a pathway that can intersect with functions of FAM86A in cell growth and survival regulation.

LY 294002

154447-36-6sc-201426
sc-201426A
5 mg
25 mg
$123.00
$400.00
148
(1)

LY294002, a flavonoid derivative, acts as a specific inhibitor of PI3Ks, affecting AKT signaling and potentially impacting the stability or activity of FAM86A through its influence on downstream signaling.

PD 98059

167869-21-8sc-3532
sc-3532A
1 mg
5 mg
$40.00
$92.00
212
(2)

PD98059 is a synthetic compound that selectively inhibits MEK, which is upstream of ERK in the MAPK pathway; this pathway can interplay with FAM86A's role within the cell, thus affecting its function.

U-0126

109511-58-2sc-222395
sc-222395A
1 mg
5 mg
$64.00
$246.00
136
(2)

U0126 is a non-competitive inhibitor of MEK1/2, which disrupts the MAPK/ERK pathway, potentially altering the activity and cellular localization of FAM86A.

SB 203580

152121-47-6sc-3533
sc-3533A
1 mg
5 mg
$90.00
$349.00
284
(5)

SB203580 is a pyridinyl imidazole derivative that specifically inhibits p38 MAPK, potentially modifying the function of FAM86A if it is involved in stress response signaling.

SP600125

129-56-6sc-200635
sc-200635A
10 mg
50 mg
$40.00
$150.00
257
(3)

SP600125 is an anthrapyrazolone inhibitor of JNK, impacting the JNK signaling pathway and possibly affecting the function of FAM86A if it is associated with stress signaling pathways.

Rapamycin

53123-88-9sc-3504
sc-3504A
sc-3504B
1 mg
5 mg
25 mg
$63.00
$158.00
$326.00
233
(4)

Rapamycin is a macrolide compound that inhibits mTOR, which can affect cell growth and proliferation, thereby influencing the activity of FAM86A if linked to these processes.

Cyclopamine

4449-51-8sc-200929
sc-200929A
1 mg
5 mg
$94.00
$208.00
19
(1)

Cyclopamine is a steroidal alkaloid that inhibits smoothened, a component of the Hedgehog signaling pathway, potentially affecting FAM86A if it is implicated in developmental signaling processes.

Y-27632, free base

146986-50-7sc-3536
sc-3536A
5 mg
50 mg
$186.00
$707.00
88
(1)

Y-27632 is a selective inhibitor of ROCK, affecting cytoskeletal organization and cell motility, possibly impacting FAM86A if it plays a role in these cellular functions.

PP 2

172889-27-9sc-202769
sc-202769A
1 mg
5 mg
$94.00
$227.00
30
(1)

PP2 is an inhibitor of Src family kinases, which are involved in various signaling pathways, possibly altering the function or expression of FAM86A through its broad spectrum of activity.