FAM84A Activators
Chemical activators of FAM84A are diverse in their mechanisms of action, each potentially influencing the expression or function of FAM84A through indirect modulation of cellular pathways and gene expression mechanisms. DNA methyltransferase inhibitors, such as 5-Azacytidine, can lead to widespread changes in the epigenetic landscape, altering gene expression profiles which could include FAM84A. The upregulation of genes, including FAM84A, can also occur through the inhibition of histone deacetylases by compounds such as SAHA, Trichostatin A, and Sodium butyrate. These compounds increase the accessibility of transcription factors to the DNA by altering the chromatin structure.
Moreover, signaling molecules like retinoic acid and hormones such as beta-estradiol engage with their respective receptors to modulate gene expression in a wide array of biological processes. Such regulatory activities can result in the increased expression of genes like FAM84A, which may play roles in cellular differentiation and response to hormonal signals. Glucocorticoids, including Dexamethasone, mediate anti-inflammatory responses and metabolic effects that often involve changes in gene expression, potentially affecting FAM84A levels. Additionally, activators of metabolic sensors like AICAR or modulators of signaling pathways such as mTOR inhibitors (e.g., Rapamycin) and Lithium chloride, can induce complex alterations in the cellular regulatory networks that may result in the enhanced expression of FAM84A as part of the cellular adaptive responses.
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
A DNA methyltransferase inhibitor that can lead to demethylation and upregulation of genes, potentially increasing FAM84A expression as a consequence of changes in epigenetic regulation. | ||||||
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $130.00 $270.00 | 37 | |
A histone deacetylase inhibitor that may enhance transcription of certain genes by altering chromatin structure, potentially including FAM84A. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
A metabolite of vitamin A that acts as a ligand for retinoic acid receptors, affecting gene expression; could upregulate FAM84A as part of the modulation of cellular differentiation pathways. | ||||||
β-Estradiol | 50-28-2 | sc-204431 sc-204431A | 500 mg 5 g | $62.00 $178.00 | 8 | |
As a primary female sex hormone, it acts as a transcriptional regulator for specific genes and could influence the expression of FAM84A indirectly through estrogen-receptor mediated signaling. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $76.00 $82.00 $367.00 | 36 | |
A glucocorticoid that can modulate gene expression and may increase FAM84A levels as part of the glucocorticoid response elements within the genome. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
Another histone deacetylase inhibitor, like SAHA, that may result in the increased expression of several genes, possibly including FAM84A due to changes in chromatin accessibility. | ||||||
AICAR | 2627-69-2 | sc-200659 sc-200659A sc-200659B | 50 mg 250 mg 1 g | $60.00 $270.00 $350.00 | 48 | |
Activates AMPK, a master regulator of metabolic stress, which could lead to the transcriptional regulation of a wide range of genes, potentially including FAM84A. | ||||||
Rosiglitazone | 122320-73-4 | sc-202795 sc-202795A sc-202795C sc-202795D sc-202795B | 25 mg 100 mg 500 mg 1 g 5 g | $118.00 $320.00 $622.00 $928.00 $1234.00 | 38 | |
As agonists of the PPARγ receptor, they modulate gene expression and could influence FAM84A expression as part of the regulatory processes controlling lipid metabolism and insulin sensitivity. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $30.00 $46.00 $82.00 $218.00 | 19 | |
Acts as a histone deacetylase inhibitor and could potentially increase the expression of genes, including FAM84A, by affecting chromatin structure and gene accessibility. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Influences glycogen synthase kinase 3 (GSK-3) activity, which is involved in numerous signaling pathways, including those related to gene expression and could impact the expression level of FAM84A. | ||||||