FAM75A3 Inhibitors
The chemical class of FAM75A3 Inhibitors comprises a diverse range of compounds that can potentially inhibit the activity of the FAM75A3 protein, either directly or indirectly. FAM75A3 is likely involved in cellular processes regulated by signaling pathways such as phosphoinositide 3-kinase (PI3K), mitogen-activated protein kinase (MAPK), nuclear factor kappa B (NF-κB), and others.
Direct inhibitors such as rapamycin, LY294002, U0126, SB203580, SP600125, Wortmannin, BAY 11-7082, PD98059, SP600125, TPCA-1, AZD6244, and BIRB 796 can target specific kinases or signaling molecules involved in these pathways, potentially disrupting cellular processes that rely on FAM75A3 function. Indirect inhibitors exert their effects by modulating cellular responses and signaling cascades that intersect with FAM75A3-mediated pathways, ultimately influencing the activity of FAM75A3. These inhibitors provide valuable tools for investigating the physiological roles of FAM75A3 and may have implications in diseases where dysregulation of FAM75A3-associated pathways occurs.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Rapamycin is a macrolide antibiotic that inhibits the activity of mammalian target of rapamycin (mTOR), a kinase involved in cellular growth and proliferation pathways. Inhibition of mTOR by rapamycin can disrupt downstream signaling cascades, potentially affecting cellular processes regulated by FAM75A3. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
LY294002 is a potent inhibitor of phosphoinositide 3-kinases (PI3Ks), enzymes involved in intracellular signaling pathways related to cell survival, proliferation, and metabolism. Inhibition of PI3Ks by LY294002 can modulate downstream signaling events, potentially influencing the activity of FAM75A3, which may be linked to PI3K-dependent pathways. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $63.00 $241.00 | 136 | |
U0126 is a selective inhibitor of mitogen-activated protein kinase kinase (MEK), a key component of the extracellular signal-regulated kinase (ERK) signaling pathway. Inhibition of MEK by U0126 can disrupt ERK signaling, potentially impacting cellular processes regulated by FAM75A3, which may be modulated by ERK-dependent mechanisms. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
SB203580 is a selective inhibitor of p38 mitogen-activated protein kinase (MAPK), which plays a role in cellular stress responses and inflammation. Inhibition of p38 MAPK by SB203580 can modulate signaling pathways involved in stress-induced cellular processes, potentially influencing the activity of FAM75A3, which may be regulated by p38 MAPK-dependent mechanisms. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
SP600125 is a potent inhibitor of c-Jun N-terminal kinase (JNK), a member of the MAPK family involved in the regulation of cell proliferation, apoptosis, and inflammation. Inhibition of JNK by SP600125 can modulate downstream signaling events, potentially affecting cellular processes regulated by FAM75A3, which may be linked to JNK-dependent pathways. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
Wortmannin is a potent inhibitor of phosphoinositide 3-kinases (PI3Ks), enzymes involved in intracellular signaling pathways related to cell survival, proliferation, and metabolism. Inhibition of PI3Ks by wortmannin can disrupt downstream signaling events, potentially influencing the activity of FAM75A3, which may be regulated by PI3K-dependent mechanisms. | ||||||
BAY 11-7082 | 19542-67-7 | sc-200615B sc-200615 sc-200615A | 5 mg 10 mg 50 mg | $61.00 $83.00 $349.00 | 155 | |
BAY 11-7082 is an inhibitor of nuclear factor kappa B (NF-κB) activation, a transcription factor involved in the regulation of inflammation, immunity, and cell survival. Inhibition of NF-κB by BAY 11-7082 can modulate gene expression profiles and cellular responses, potentially impacting the activity of FAM75A3, which may be regulated by NF-κB-dependent mechanisms. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
PD98059 is a selective inhibitor of mitogen-activated protein kinase kinase (MEK), which acts upstream of extracellular signal-regulated kinase (ERK) in the ERK signaling pathway. Inhibition of MEK by PD98059 can disrupt ERK signaling, potentially influencing cellular processes regulated by FAM75A3, which may be modulated by ERK-dependent mechanisms. | ||||||
IKK-2 Inhibitor IV | 507475-17-4 | sc-203083 | 500 µg | $130.00 | 12 | |
TPCA-1 is an inhibitor of IKK-2, a kinase involved in the activation of nuclear factor kappa B (NF-κB), a transcription factor regulating inflammation and immune responses. Inhibition of IKK-2 by TPCA-1 can disrupt NF-κB signaling, potentially influencing the activity of FAM75A3, which may be regulated by NF-κB-dependent mechanisms. | ||||||
Doramapimod | 285983-48-4 | sc-300502 sc-300502A sc-300502B | 25 mg 50 mg 100 mg | $149.00 $281.00 $459.00 | 2 | |
BIRB 796 is a potent inhibitor of p38 mitogen-activated protein kinase (MAPK), which plays a role in cellular stress responses and inflammation. Inhibition of p38 MAPK by BIRB 796 can modulate signaling pathways involved in stress-induced cellular processes, potentially influencing the activity of FAM75A3, which may be regulated by p38 MAPK-dependent mechanisms. | ||||||