FAM72B Inhibitors
Items 1 to 10 of 12 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Palbociclib | 571190-30-2 | sc-507366 | 50 mg | $315.00 | ||
Directly inhibits CDK4/6, halting progression from G1 to S phase of the cell cycle, where FAM72B may play a role in DNA replication initiation. | ||||||
AZD 5438 | 602306-29-6 | sc-361115 sc-361115A | 10 mg 50 mg | $205.00 $865.00 | ||
Targets CDK1/2/9, influencing the transition and progression of various cell cycle phases, which may counteract FAM72B's function in promoting cell proliferation. | ||||||
Roscovitine | 186692-46-6 | sc-24002 sc-24002A | 1 mg 5 mg | $92.00 $260.00 | 42 | |
By inhibiting CDKs, Roscovitine disrupts cell cycle progression, countering potential actions of FAM72B in cycle transitions. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $63.00 $241.00 | 136 | |
This MEK inhibitor interrupts the downstream activation of ERK, a regulator of cell proliferation, thereby affecting the milieu where FAM72B functions. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
JNK inhibitor that, when blocked, prevents downstream effects on factors like c-Jun, potentially attenuating cell proliferation roles linked to FAM72B. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
By inhibiting p38 MAPK, this compound disrupts cellular responses to stress, which may influence the stability or activity of FAM72B under stress conditions. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
By blocking PI3K, this inhibitor attenuates Akt signaling, a critical pathway in cell survival and growth, and thus may modify the cellular context in which FAM72B operates. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
As an mTOR inhibitor, Rapamycin affects protein synthesis and cell growth, potentially altering the balance of factors that interact with or are modulated by FAM72B. | ||||||
ZM-447439 | 331771-20-1 | sc-200696 sc-200696A | 1 mg 10 mg | $150.00 $349.00 | 15 | |
This Aurora kinase inhibitor affects chromosome alignment and segregation, challenging FAM72B's potential role in maintaining genomic stability during cell division. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
Specifically targets MEK, impacting ERK activation. Since ERK affects cell proliferation, this may change the proliferation rate wherein FAM72B functions. | ||||||