Date published: 2026-4-6

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FAM55A Inhibitors

FAM55A inhibitors are a class of chemical compounds that indirectly affect the functional activity of the protein FAM55A through various signaling pathways. PI3K inhibitors like LY294002 and Wortmannin can lead to the abrogation of the PI3K/AKT pathway, potentially impacting FAM55A if it is involved in the downstream signaling of this pathway. Similarly, by inhibiting the mTORC1 complex with rapamycin, one can suppress the cellular growth and proliferation signals that FAM55A might be involved in regulating. MEK inhibitors such as PD98059 and U0126 prevent the activation of the ERK pathway, which could result in the indirect inhibition of FAM55A if it is a part of ERK-regulated cellular activities. By blocking these pathways, the functional activity of FAM55A can be indirectly diminished. Furthermore, the use of MAPK pathway inhibitors, including SB203580 for p38 MAPK, SP600125 for JNK, and PP2 for Src family kinases, can reduce the signaling that potentially involves FAM55A. If FAM55A operates within these stress or inflammation-related signaling pathways, its activity would be diminished by these inhibitors. PKC inhibitors, such as GF109203X and Calphostin C, can lead to the inhibition of PKC-mediated signaling, thereby potentially decreasing the functional activity of FAM55A if it is associated with PKC signaling pathways. Dasatinib, as a broad tyrosine kinase inhibitor, and AG490, as a JAK2 inhibitor, can suppress various tyrosine kinase-dependent pathways, which could indirectly impact the signaling events where FAM55A is involved, especially if tyrosine phosphorylation is a key factor for FAM55A's functionality.

Items 1 to 10 of 12 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

LY 294002

154447-36-6sc-201426
sc-201426A
5 mg
25 mg
$123.00
$400.00
148
(1)

A specific inhibitor of PI3K, LY294002 can lead to the inhibition of the PI3K/AKT signaling pathway. Since FAM55A is implicated in cell signaling, inhibiting PI3K can prevent AKT activation, which in turn could prevent any downstream signaling required for FAM55A functional activity.

PD 98059

167869-21-8sc-3532
sc-3532A
1 mg
5 mg
$40.00
$92.00
212
(2)

An inhibitor of MEK, which is upstream of ERK in the MAPK pathway. FAM55A's activity could be indirectly inhibited if ERK signaling is reduced, as this pathway is often involved in the regulation of various cellular activities that FAM55A may influence.

SB 203580

152121-47-6sc-3533
sc-3533A
1 mg
5 mg
$90.00
$349.00
284
(5)

A p38 MAPK inhibitor, SB203580 can prevent the activation of p38 MAPK, which is involved in inflammatory responses and stress-induced signaling. If FAM55A is responsive to these stimuli, inhibiting p38 MAPK can lead to reduced FAM55A signaling activity.

SP600125

129-56-6sc-200635
sc-200635A
10 mg
50 mg
$40.00
$150.00
257
(3)

An inhibitor of JNK, another MAPK pathway component. FAM55A, if it interacts with JNK-dependent signaling pathways, would have decreased activity as a result of JNK inhibition, which could block stress and apoptosis-related signaling events.

Wortmannin

19545-26-7sc-3505
sc-3505A
sc-3505B
1 mg
5 mg
20 mg
$67.00
$223.00
$425.00
97
(3)

Another PI3K inhibitor, wortmannin can lead to inhibition of the PI3K/AKT pathway similar to LY294002. By inhibiting PI3K, it can prevent downstream effects that may include the functional activity of FAM55A.

Rapamycin

53123-88-9sc-3504
sc-3504A
sc-3504B
1 mg
5 mg
25 mg
$63.00
$158.00
$326.00
233
(4)

An mTOR inhibitor, rapamycin inhibits the mTORC1 complex, which is downstream of PI3K/AKT signaling. Given that mTOR is involved in cellular growth and proliferation, FAM55A's role in these processes could be indirectly inhibited through mTOR inhibition.

PP 2

172889-27-9sc-202769
sc-202769A
1 mg
5 mg
$94.00
$227.00
30
(1)

A Src family kinase inhibitor, PP2 can inhibit signaling pathways that involve Src kinases. If FAM55A is part of signaling cascades that involve Src kinase activity, its functional activity could be indirectly diminished by PP2.

U-0126

109511-58-2sc-222395
sc-222395A
1 mg
5 mg
$64.00
$246.00
136
(2)

Another ERK pathway inhibitor, U0126 specifically inhibits MEK1/2, blocking ERK1/2 activation. This could lead to the inhibition of cellular processes that involve FAM55A if it is regulated by ERK signaling.

Bisindolylmaleimide I (GF 109203X)

133052-90-1sc-24003A
sc-24003
1 mg
5 mg
$105.00
$242.00
36
(1)

An inhibitor of protein kinase C (PKC), GF109203X could indirectly inhibit FAM55A's function by blocking PKC-mediated signaling pathways, which are involved in various cellular responses.

Dasatinib

302962-49-8sc-358114
sc-358114A
25 mg
1 g
$70.00
$145.00
51
(1)

A broad tyrosine kinase inhibitor, dasatinib can inhibit multiple kinases, potentially reducing the activity of pathways where FAM55A is relevant, particularly if tyrosine phosphorylation is involved in FAM55A's function.